PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

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6K39	Structural analysis of AIMP2-DX2 and HSP70 interaction 分子名称: Heat shock 70 kDa protein 1A,Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 著者 Cho, H.Y, Son, S.Y, Jeon, Y.H. 登録日 2019-05-16 公開日 2019-10-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.3981427 Å) 主引用文献 Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development. Nat.Chem.Biol., 16, 2020
5YHN	Solution structure of the LEKTI Domain 4 分子名称: cDNA FLJ60407, highly similar to Serine protease inhibitor Kazal-type 5 著者 Mok, Y.K, Ramesh, K. 登録日 2017-09-29 公開日 2018-08-08 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Homologous Lympho-Epithelial Kazal-type Inhibitor Domains Delay Blood Coagulation by Inhibiting Factor X and XI with Differential Specificity. Structure, 26, 2018
5XYL	Solution Structure of Skp1 from Homo sapiens 分子名称: S-phase kinase-associated protein 1 著者 Shukla, V.K, Kachariya, N.N, Bhattacharya, A, Dantu, S.C, Kumar, A. 登録日 2017-07-09 公開日 2018-07-11 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural and dynamics insight of the recognition of Fbox protein by Skp1 To Be Published
5Y0U	The solution structure of AEBP2 C2H2 zinc fingers 分子名称: ZINC ION, Zinc finger protein AEBP2 著者 Sun, A, Shi, Y, Wu, J. 登録日 2017-07-18 公開日 2018-08-01 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4. Protein Cell, 9, 2018
5YI9	Solution structure of the LEDGF/p75 IBD - JPO2 (aa 56-91) complex 分子名称: PC4 and SFRS1-interacting protein,Cell division cycle-associated 7-like protein 著者 Veverka, V. 登録日 2017-10-03 公開日 2018-08-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ND9	Hibernating ribosome from Staphylococcus aureus (Rotated state) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Khusainov, I, Vicens, Q, Ayupov, R, Usachev, K, Myasnikov, A, Simonetti, A, Validov, S, Kieffer, B, Yusupova, G, Yusupov, M, Hashem, Y. 登録日 2017-03-07 公開日 2017-06-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF. EMBO J., 36, 2017
6I79	SEPIAPTERIN REDUCTASE IN COMPLEX WITH COMPOUND 4 分子名称: 6-[(4-~{tert}-butyl-1,3-thiazol-2-yl)methyl]-4,6-diazaspiro[2.4]heptane-5,7-dione, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Sepiapterin reductase 著者 Alen, J, Schade, M, Wagener, M, Blaesse, M. 登録日 2018-11-16 公開日 2019-07-10 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors. J.Med.Chem., 62, 2019
6HFM	Hsp90 co-chaperone Cns1 C-domain from Saccharomyces cerevisiae 分子名称: Hsp70/Hsp90 co-chaperone CNS1, MAGNESIUM ION 著者 Huber, E.M, Groll, M. 登録日 2018-08-21 公開日 2019-03-27 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2. Mol.Cell, 74, 2019
6HMH	Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with alpha-Glc-1,3-(1,2-anhydro-carba-glucosamine) and alpha-1,2-mannobiose 分子名称: (1~{S},2~{R},3~{R},4~{R},6~{S})-4-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3-diol, ACETATE ION, Glycosyl hydrolase family 71, ... 著者 Sobala, L.F, Lu, D, Zhu, S, Bernardo-Seisdedos, G, Millet, O, Zhang, Y, Sollogoub, M, Jimenez-Barbero, J, Davies, G.J. 登録日 2018-09-12 公開日 2018-09-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-alpha-mannosidase. Org.Lett., 20, 2018
6HNM	Crystal structure of IdmH 96-104 loop truncation variant 分子名称: putative polyketide cyclase IdmH 著者 Drulyte, I, Obajdin, J, Trinh, C, Hemsworth, G.R, Berry, A. 登録日 2018-09-16 公開日 2019-11-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase. Iucrj, 6, 2019
6HIP	Structure of SPF45 UHM bound to HIV-1 Rev ULM 分子名称: HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ... 著者 Pabis, M, Corsini, L, Sattler, M. 登録日 2018-08-30 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors. Nucleic Acids Res., 47, 2019
6HZF	BP0997, GH138 enzyme targeting pectin rhamnogalacturonan II 分子名称: BPa0997, SERINE, SODIUM ION 著者 Basle, A, Cartmell, A, Labourel, A, Gilbert, H. 登録日 2018-10-23 公開日 2019-03-20 最終更新日 2019-05-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and functional analyses of glycoside hydrolase 138 enzymes targeting chain A galacturonic acid in the complex pectin rhamnogalacturonan II. J.Biol.Chem., 294, 2019
5Z9R	NMNAT as a specific chaperone antagonizing pathological condensation of phosphorylated tau 分子名称: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 著者 Dou, S, Ma, X, Li, D, Liu, C. 登録日 2018-02-05 公開日 2019-02-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Nicotinamide mononucleotide adenylyltransferase uses its NAD+substrate-binding site to chaperone phosphorylated Tau. Elife, 9, 2020
6HE6	Crystal structure of Extracellular Domain 1 (ECD1) of FtsX from S. pneumonie in complex with dodecane-trimethylamine 分子名称: Cell division protein FtsX, DODECANE-TRIMETHYLAMINE 著者 Martinez-Caballero, S, Alcorlo-Pages, M, Hermoso, J.A. 登録日 2018-08-20 公開日 2019-04-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae. Mbio, 10, 2019
5YVG	Crystal structure of Karyopherin beta2 in complex with FUS(full length) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4.05 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
5MGF	Crystal Structure of BAZ2B bromodomain in complex with 4-propionyl-pyrrole derivative 2 分子名称: Bromodomain adjacent to zinc finger domain protein 2B, methyl 4-propanoyl-1~{H}-pyrrole-2-carboxylate 著者 Lolli, G, Spiliotopoulos, D, Caflisch, A. 登録日 2016-11-21 公開日 2017-04-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of BAZ2A bromodomain ligands. Eur J Med Chem, 139, 2017
5WL6	Crystal structure of chalcone isomerase engineered from ancestral inference (AncR7) 分子名称: CHLORIDE ION, Engineered Chalcone Isomerase AncR7 著者 Burke, J.R, Kaltenbach, M, Tawfik, D.S, Noel, J.P. 登録日 2017-07-25 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Evolution of chalcone isomerase from a noncatalytic ancestor. Nat. Chem. Biol., 14, 2018
5WI1	Crystal structure of human NAMPT with fragment 5: (3E)-3-[(phenylamino)methylidene]oxan-2-one 分子名称: (3E)-3-[(phenylamino)methylidene]oxan-2-one, Nicotinamide phosphoribosyltransferase, SULFATE ION 著者 Longenecker, K.L, Raich, D, Korepanova, A.V. 登録日 2017-07-18 公開日 2018-01-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Fragment-based discovery of a potent NAMPT inhibitor. Bioorg. Med. Chem. Lett., 28, 2018
6HAT	Globular domain of herpesvirus saimiri ORF57 分子名称: ACETATE ION, ZINC ION, mRNA export factor ICP27 homolog 著者 Tunnicliffe, R.B, Levy, C, Ruiz Nivia, H.D, Sandri-Goldin, R.M, Golovanov, A.P. 登録日 2018-08-08 公開日 2018-11-21 最終更新日 2022-03-30 実験手法 X-RAY DIFFRACTION (1.856 Å) 主引用文献 Structural identification of conserved RNA binding sites in herpesvirus ORF57 homologs: implications for PAN RNA recognition. Nucleic Acids Res., 47, 2019
5NP5	Abl2 SH3 pTyr116/161 分子名称: Abelson tyrosine-protein kinase 2, SULFATE ION 著者 Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L. 登録日 2017-04-13 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions. J.Biol.Chem., 294, 2019
6HDI	R49A variant of beta-phosphoglucomutase from Lactococcus lactis in an open conformer to 2.0 A. 分子名称: 1,2-ETHANEDIOL, Beta-phosphoglucomutase, MAGNESIUM ION 著者 Robertson, A.J, Bisson, C, Waltho, J.P. 登録日 2018-08-17 公開日 2020-08-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Transition state of phospho-enzyme hydrolysis in beta-phosphoglucomutase. To Be Published
6HDL	R49K variant of beta-phosphoglucomutase from Lactococcus lactis complexed with magnesium trifluoride and beta-G6P to 1.2 A. 分子名称: 1,2-ETHANEDIOL, 6-O-phosphono-beta-D-glucopyranose, Beta-phosphoglucomutase, ... 著者 Wood, H.P, Robertson, A.J, Bisson, C, Waltho, J.P. 登録日 2018-08-17 公開日 2020-08-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Transition state of phospho-enzyme hydrolysis in beta-phosphoglucomutase. To Be Published
6HAG	The structure of the SAM/SAH-binding riboswitch. 分子名称: S-ADENOSYL-L-HOMOCYSTEINE, SAM Riboswitch 著者 Weickhmann, A.K. 登録日 2018-08-07 公開日 2019-01-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The structure of the SAM/SAH-binding riboswitch. Nucleic Acids Res., 47, 2019
6HZZ	Structure of human D-glucuronyl C5 epimerase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Debarnot, C, Monneau, Y.R, Roig-Zamboni, V, Le Narvor, C, Goulet, A, Fadel, F, Vives, R.R, Bonnaffe, D, Lortat-Jacob, H, Bourne, Y. 登録日 2018-10-24 公開日 2019-04-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase. Proc.Natl.Acad.Sci.USA, 116, 2019
6HDK	R49A variant of beta-phosphoglucomutase from Lactococcus lactis complexed with aluminium tetrafluoride and beta-G6P to 1.2 A. 分子名称: 1,2-ETHANEDIOL, 6-O-phosphono-beta-D-glucopyranose, Beta-phosphoglucomutase, ... 著者 Robertson, A.J, Bisson, C, Waltho, J.P. 登録日 2018-08-17 公開日 2020-08-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Transition state of phospho-enzyme hydrolysis in beta-phosphoglucomutase. To Be Published

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