PDB: 5591 件ウェブページステータス検索Chemie searchBIRD

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5K2G	Structure of GNNQQNY from yeast prion Sup35 in space group P21 determined by MicroED 分子名称: Eukaryotic peptide chain release factor GTP-binding subunit 著者 Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S. 登録日 2016-05-18 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 ELECTRON CRYSTALLOGRAPHY (1.1 Å) 主引用文献 Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED. Proc.Natl.Acad.Sci.USA, 113, 2016
4E76	Apo crystal structure of HCV NS5B genotype 2A JFH-1 isolate with beta hairpin loop deletion 分子名称: 1,2-ETHANEDIOL, RNA-directed RNA polymerase, SULFATE ION 著者 Edwards, T.E, Mosley, R.T. 登録日 2012-03-16 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of hepatitis C virus polymerase in complex with primer-template RNA. J.Virol., 86, 2012
4E78	Crystal structure of a product state assembly of HCV NS5B genotype 2a JFH-1 isolate with beta hairpin loop deletion bound to primer-template RNA with 3'-dG 分子名称: 5'-R(*U*AP*CP*CP*GP*(GDO))-3', PROTEIN (RNA-directed RNA polymerase) 著者 Edwards, T.E, Mosley, R.T. 登録日 2012-03-16 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of hepatitis C virus polymerase in complex with primer-template RNA. J.Virol., 86, 2012
4H7Z	tRNA-guanine transglycosylase Y106F, C158V mutant in complex with guanine 分子名称: GLYCEROL, GUANINE, Queuine tRNA-ribosyltransferase, ... 著者 Biela, I, Tidten-Luksch, N, Heine, A, Reuter, K, Klebe, G. 登録日 2012-09-21 公開日 2012-10-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8, 2013
4H6E	tRNA-guanine transglycosylase Y106F, C158V, V233G mutant apo structure 分子名称: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION 著者 Biela, I, Tidten-Luksch, N, Heine, A, Reuter, K, Klebe, G. 登録日 2012-09-19 公開日 2012-11-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8, 2013
4E7A	Crystal structure of a product state assembly of HCV NS5B genotype 2a JFH-1 isolate with beta hairpin deletion bound to primer-template RNA with a 2',3'-ddC 分子名称: 5'-R(*CP*AP*UP*GP*GP*C)-D(P*(DOC))-3', RNA-directed RNA polymerase 著者 Edwards, T.E, Mosley, R.T. 登録日 2012-03-16 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of hepatitis C virus polymerase in complex with primer-template RNA. J.Virol., 86, 2012
4HSH	tRNA-guanine transglycosylase Y106F, V233G mutant in complex with queuine 分子名称: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Biela, I, Tidten-Luksch, N, Heine, A, Reuter, K, Klebe, G. 登録日 2012-10-30 公開日 2012-11-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8, 2013
4GD0	tRNA-guanine transglycosylase Y106F, C158V mutant 分子名称: GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION 著者 Schmidt, I, Tidten-Luksch, N, Heine, A, Reuter, K, Klebe, G. 登録日 2012-07-31 公開日 2012-08-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8, 2013
4HVX	tRNA-guanine transglycosylase Y106F, C158V mutant in complex with queuine 分子名称: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Biela, I, Tidten-Luksch, N, Heine, A, Reuter, K, Klebe, G. 登録日 2012-11-07 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8, 2013
4HQV	tRNA-guanine transglycosylase Y106F, C158V, V233G mutant in complex with queuine 分子名称: 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Biela, I, Tidten-Luksch, N, Heine, A, Reuter, K, Klebe, G. 登録日 2012-10-26 公開日 2012-11-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8, 2013
3P96	Crystal structure of Phosphoserine phosphatase SerB from Mycobacterium avium, native form 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-10-15 公開日 2010-11-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 SAD phasing using iodide ions in a high-throughput structural genomics environment. J.Struct.Funct.Genom., 12, 2011
3QBH	Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors 分子名称: (4S)-4-(2-hydroxy-5-{[(3S,4S,5R)-4-hydroxy-1,1-dioxido-5-{[3-(propan-2-yl)benzyl]amino}tetrahydro-2H-thiopyran-3-yl]methyl}benzyl)-3-propyl-1,3-oxazolidin-2-one, Beta-secretase 1 著者 Rondeau, J.M. 登録日 2011-01-13 公開日 2011-03-23 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
3PM6	Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR 分子名称: IODIDE ION, Putative fructose-bisphosphate aldolase, ZINC ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-11-16 公開日 2010-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 SAD phasing using iodide ions in a high-throughput structural genomics environment. J Struct Funct Genomics, 12, 2011
3OGZ	Protein structure of USP from L. major in Apo-form 分子名称: GLYCEROL, UDP-sugar pyrophosphorylase 著者 Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. 登録日 2010-08-17 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
3OH0	Protein structure of USP from L. major bound to URIDINE-5'-TRIPHOSPHATE 分子名称: GLYCEROL, UDP-sugar pyrophosphorylase, URIDINE 5'-TRIPHOSPHATE 著者 Dickmanns, A, Damerow, S, Neumann, P, Schulz, E.-C, Lamerz, A, Routier, F, Ficner, R. 登録日 2010-08-17 公開日 2010-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major. J.Mol.Biol., 405, 2011
3STX	Crystal Structure of tomato Methylketone Synthase I H243A variant complexed with beta-ketoheptanoate 分子名称: 3-oxoheptanoic acid, Methylketone synthase 1 著者 Auldridge, M.E, Austin, M.B, Noel, J.P. 登録日 2011-07-11 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Emergent Decarboxylase Activity and Attenuation of alpha/beta-Hydrolase Activity during the Evolution of Methylketone Biosynthesis in Tomato. Plant Cell, 24, 2012
3STV	Crystal Structure of tomato Methylketone Synthase I complexed with 3-hydroxyoctanoate 分子名称: (3S)-3-hydroxyoctanoic acid, BROMIDE ION, Methylketone synthase 1 著者 Auldridge, M.E, Austin, M.B, Noel, J.P. 登録日 2011-07-11 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Emergent Decarboxylase Activity and Attenuation of alpha/beta-Hydrolase Activity during the Evolution of Methylketone Biosynthesis in Tomato. Plant Cell, 24, 2012
3STW	Crystal Structure of tomato Methylketone Synthase I complexed with 2-tridecanone 分子名称: Methylketone synthase 1, tridec-12-en-2-one 著者 Auldridge, M.E, Austin, M.B, Noel, J.P. 登録日 2011-07-11 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Emergent Decarboxylase Activity and Attenuation of alpha/beta-Hydrolase Activity during the Evolution of Methylketone Biosynthesis in Tomato. Plant Cell, 24, 2012
8B10	Crystal Structure of Shank2-SAM mutant domain - L1800W 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Bento, I, Gracia Alai, M, Kreienkamp, J.-H. 登録日 2022-09-08 公開日 2022-11-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 2022
8ATJ	Crystal Structure of Shank2-SAM domain 分子名称: CHLORIDE ION, FORMIC ACID, Isoform 4 of SH3 and multiple ankyrin repeat domains protein 2, ... 著者 Bento, I, Gracia Alai, M, Kreienkamp, J.-H. 登録日 2022-08-23 公開日 2022-11-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.117 Å) 主引用文献 Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans. Mol Psychiatry, 2022
7ZU9	CRYSTAL STRUCTURE OF THE C89A_C113A GMP SYNTHETASE INACTIVE DOUBLE MUTANT FROM PLASMODIUM FALCIPARUM 分子名称: Glutamine amidotransferase 著者 Ballut, L, Violot, S, Aghajari, N. 登録日 2022-05-11 公開日 2022-08-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Tertiary and Quaternary Structure Organization in GMP Synthetases: Implications for Catalysis. Biomolecules, 12, 2022
6Y99	hSTING mutant R232K in complex with 2',3'-cGAMP 分子名称: Stimulator of interferon genes protein, cGAMP 著者 Boura, E, Smola, M. 登録日 2020-03-06 公開日 2021-03-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.984 Å) 主引用文献 Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
6YDZ	Human wtSTING in complex with 3',3'-cGAMP 分子名称: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon protein 著者 Boura, E, Smola, M. 登録日 2020-03-23 公開日 2021-03-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
6YEA	Human wtSTING in complex with 2',2'-difluoro-3',3'-cGAMP 分子名称: 2',2'-difluoro-3',3'-cGAMP, Stimulator of interferon protein 著者 Boura, E, Smola, M. 登録日 2020-03-24 公開日 2021-03-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.805 Å) 主引用文献 Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein. Angew.Chem.Int.Ed.Engl., 60, 2021
6K61	Cryo-EM structure of the tetrameric photosystem I from a heterocyst-forming cyanobacterium Anabaena sp. PCC7120 分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... 著者 Zheng, L, Li, Y, Li, X, Zhong, Q, Li, N, Zhang, K, Zhang, Y, Chu, H, Ma, C, Li, G, Zhao, J, Gao, N. 登録日 2019-05-31 公開日 2019-10-09 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.37 Å) 主引用文献 Structural and functional insights into the tetrameric photosystem I from heterocyst-forming cyanobacteria. Nat.Plants, 5, 2019

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