4HVX
tRNA-guanine transglycosylase Y106F, C158V mutant in complex with queuine
Summary for 4HVX
Entry DOI | 10.2210/pdb4hvx/pdb |
Related | 4E2V 4GCX 4GD0 4H6E 4H7Z 4HSH |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | substrate specificity, bacterial tgt, transferase, guanine exchange enzyme, queuine, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Zymomonas mobilis subsp. mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43524.66 |
Authors | Biela, I.,Tidten-Luksch, N.,Heine, A.,Reuter, K.,Klebe, G. (deposition date: 2012-11-07, release date: 2012-12-26, Last modification date: 2023-09-20) |
Primary citation | Biela, I.,Tidten-Luksch, N.,Immekus, F.,Glinca, S.,Nguyen, T.X.,Gerber, H.D.,Heine, A.,Klebe, G.,Reuter, K. Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8:e64240-e64240, 2013 Cited by PubMed: 23704982DOI: 10.1371/journal.pone.0064240 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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