4HVX
tRNA-guanine transglycosylase Y106F, C158V mutant in complex with queuine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Queuine tRNA-ribosyltransferase | polymer | 386 | 42905.7 | 1 | UniProt (P28720) Pfam (PF01702) In PDB | Zymomonas mobilis subsp. mobilis | Guanine insertion enzyme, tRNA-guanine transglycosylase |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | A | 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one | non-polymer | 277.3 | 1 | Chemie (QEI) | |||
| 5 | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A: 1 - 386 (UniProt: P28720)
| PDB | External Database | Details |
|---|---|---|
| Phe 106 | Tyr 106 | engineered mutation |
| Val 158 | Cys 158 | engineered mutation |
| Lys 312 | Thr 312 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42905.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 619.0 | |
| All* | Total formula weight | 43524.7 |
