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1HVE
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STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
分子名称: ANNEXIN V, CALCIUM ION, SULFATE ION
著者Burger, A, Huber, R.
登録日1994-06-29
公開日1995-03-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1HMP
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THE CRYSTAL STRUCTURE OF HUMAN HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE WITH BOUND GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, HYPOXANTHINE GUANINE PHOSPHORIBOSYL-TRANSFERASE
著者Eads, J.C, Scapin, G, Xu, Y, Grubmeyer, C, Sacchettini, J.C.
登録日1994-06-03
公開日1995-06-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of human hypoxanthine-guanine phosphoribosyltransferase with bound GMP.
Cell(Cambridge,Mass.), 78, 1994
1J0X
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Crystal structure of the rabbit muscle glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, glyceraldehyde-3-phosphate dehydrogenase
著者Cowan-Jacob, S.W, Kaufmann, M, Anselmo, A.N, Stark, W, Grutter, M.G.
登録日2002-11-25
公開日2003-12-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of rabbit-muscle glyceraldehyde-3-phosphate dehydrogenase.
Acta Crystallogr.,Sect.D, 59, 2003
1HW4
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STRUCTURE OF THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS
分子名称: 1,2-ETHANEDIOL, SULFATE ION, THYMIDYLATE SYNTHASE
著者Phan, J, Steadman, J.D, Koli, S, Ding, W.C, Minor, W, Dunlap, R.B, Berger, S.H, Lebioda, L.
登録日2001-01-09
公開日2001-01-24
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors.
J.Biol.Chem., 276, 2001
1IQT
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Solution structure of the C-terminal RNA-binding domain of heterogeneous nuclear ribonucleoprotein D0 (AUF1)
分子名称: heterogeneous nuclear ribonucleoprotein D0
著者Katahira, M, Miyanoiri, Y, Enokizono, Y, Matsuda, G, Nagata, T, Ishikawa, F, Uesugi, S.
登録日2001-08-01
公開日2002-08-07
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA.
J.Mol.Biol., 311, 2001
3NC0
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Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal II)
分子名称: DI(HYDROXYETHYL)ETHER, Exportin-1, GLYCEROL, ...
著者Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
登録日2010-06-04
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
3N0E
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Crystal structure of WDR5 mutant (W330Y)
分子名称: WD repeat-containing protein 5
著者Wu, Y.-D, Wu, X.-H, Gao, Y, Chen, R.-C.
登録日2010-05-13
公開日2010-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Effect of Asp-His-Ser/Thr-Trp Tetrad on the Thermostability of WD40-Repeat Proteins
Biochemistry, 49, 2010
3NBY
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Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex
分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D.
登録日2010-06-04
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
1JM7
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Solution structure of the BRCA1/BARD1 RING-domain heterodimer
分子名称: BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1, BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN, ZINC ION
著者Brzovic, P.S, Rajagopal, P, Hoyt, D.W, King, M.-C, Klevit, R.E.
登録日2001-07-17
公開日2001-10-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
Nat.Struct.Biol., 8, 2001
1JJR
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The Three-Dimensional Structure of the C-terminal DNA Binding Domain of Human Ku70
分子名称: THYROID AUTOANTIGEN
著者Zhang, Z, Chen, Y.
登録日2001-07-09
公開日2001-10-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The three-dimensional structure of the C-terminal DNA-binding domain of human Ku70.
J.Biol.Chem., 276, 2001
1M9F
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A,A88M Complex.
分子名称: Cyclophilin A, HIV-1 Capsid
著者Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
登録日2002-07-28
公開日2003-05-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
3N5G
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Crystal Structure of histidine-tagged human thymidylate synthase
分子名称: SULFATE ION, Thymidylate synthase
著者Pozzi, C, Cardinale, D, Guaitoli, G, Tondi, D, Luciani, R, Myllykallio, H, Ferrari, S, Costi, M.P, Mangani, S.
登録日2010-05-25
公開日2011-06-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 108, 2011
3NAU
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Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)
分子名称: SULFATE ION, Zinc fingers and homeoboxes protein 2
著者Ren, J, Bird, L.E, Owens, R.J, Stammers, D.K, Oxford Protein Production Facility (OPPF)
登録日2010-06-02
公開日2010-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains
Bmc Struct.Biol., 10, 2010
3PSL
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Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3 based peptide mimetic
分子名称: N-alpha acetylated form of histone H3, WD repeat-containing protein 5
著者Avdic, V, Zhang, P, Lanouette, S, Voronova, A, Skerjanc, I, Couture, J.-F.
登録日2010-12-01
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic.
Faseb J., 25, 2011
3QBY
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Crystal structure of the PWWP domain of human Hepatoma-derived growth factor 2
分子名称: H4K20me3 Histone H4 Peptide, Hepatoma-derived growth factor-related protein 2, SULFATE ION, ...
著者Zeng, H, Tempel, W, Amaya, M.F, Adams-Cioaba, M.A, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2011-01-14
公開日2011-02-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and Histone Binding Ability Characterizations of Human PWWP Domains.
Plos One, 6, 2011
3ODI
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Crystal structure of cyclophilin A in complex with Voclosporin E-ISA247
分子名称: Cyclophilin A, Voclosporin
著者Kuglstatter, A, Stihle, M, Benz, J, Hennig, M.
登録日2010-08-11
公開日2011-02-16
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin).
Acta Crystallogr.,Sect.D, 67, 2011
3ODL
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Crystal structure of cyclophilin A in complex with Voclosporin Z-ISA247
分子名称: Cyclophilin A, Voclosporin
著者Kuglstatter, A, Stihle, M, Benz, J, Hennig, M.
登録日2010-08-11
公開日2011-02-16
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin).
Acta Crystallogr.,Sect.D, 67, 2011
3O8V
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Crystal Structure of the Tudor Domains from FXR1
分子名称: Fragile X mental retardation syndrome-related protein 1
著者Lam, R, Guo, Y.H, Adams-Cioaba, M, Bian, C.B, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2010-08-03
公開日2010-08-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2.
Plos One, 5, 2010
1M9D
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) O-type chimera Complex.
分子名称: Cyclophilin A, HIV-1 Capsid
著者Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
登録日2002-07-28
公開日2003-05-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1HVD
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STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
分子名称: ANNEXIN V, CALCIUM ION
著者Burger, A, Huber, R.
登録日1994-06-29
公開日1995-03-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1HVF
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BU of 1hvf by Molmil
STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
分子名称: ANNEXIN V, CALCIUM ION, SULFATE ION
著者Burger, A, Huber, R.
登録日1994-06-29
公開日1995-03-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1HVG
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STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
分子名称: ANNEXIN V
著者Burger, A, Huber, R.
登録日1994-06-29
公開日1995-03-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1M9C
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X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type Complex.
分子名称: Cyclophilin A, HIV-1 Capsid
著者Howard, B.R, Vajdos, F.F, Li, S, Sundquist, W.I, Hill, C.P.
登録日2002-07-28
公開日2003-05-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the catalytic mechanism of cyclophilin A
Nat.Struct.Biol., 10, 2003
1M63
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Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes
分子名称: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CYCLOSPORIN A, ...
著者Huai, Q, Kim, H.-Y, Liu, Y, Zhao, Y, Mondragon, A, Liu, J.O, Ke, H.
登録日2002-07-12
公開日2002-09-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Calcineurin-Cyclophilin-Cyclosporin Shows Common But Distinct Recognition of Immunophilin-Drug Complexes
Proc.Natl.Acad.Sci.USA, 99, 2002
1MF8
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Crystal Structure of human calcineurin complexed with cyclosporin A and human cyclophilin
分子名称: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CALMODULIN-DEPENDENT CALCINEURIN A SUBUNIT, ...
著者Jin, L, Harrison, S.C.
登録日2002-08-09
公開日2002-10-16
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human Calcineurin Complexed with Cyclosporin a and Human Cyclophilin
Proc.Natl.Acad.Sci.USA, 99, 2002

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