3WO4
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![BU of 3wo4 by Molmil](/molmil-images/mine/3wo4) | Crystal structure of the IL-18 signaling ternary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. | 登録日 | 2013-12-19 | 公開日 | 2014-12-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
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7W1P
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![BU of 7w1p by Molmil](/molmil-images/mine/7w1p) | Deactive state CI from Q10-NADH dataset, Subclass 2 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-19 | 公開日 | 2022-12-28 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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7W4L
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![BU of 7w4l by Molmil](/molmil-images/mine/7w4l) | Deactive state CI from Q1-NADH dataset, Subclass 3 | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Gu, J, Yang, M. | 登録日 | 2021-11-28 | 公開日 | 2023-01-25 | 最終更新日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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2FJH
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3WO3
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![BU of 3wo3 by Molmil](/molmil-images/mine/3wo3) | Crystal structure of IL-18 in complex with IL-18 receptor alpha | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. | 登録日 | 2013-12-19 | 公開日 | 2014-12-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
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6D3O
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1VG2
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![BU of 1vg2 by Molmil](/molmil-images/mine/1vg2) | Crystal Structure Of Octaprenyl Pyrophosphate Synthase From Hyperthermophilic Thermotoga Maritima A76Y mutant | 分子名称: | octoprenyl-diphosphate synthase | 著者 | Guo, R.T, Kuo, C.J, Ko, T.P, Chou, C.C, Liang, P.H, Wang, A.H.-J. | 登録日 | 2004-04-23 | 公開日 | 2004-05-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A molecular ruler for chain elongation catalyzed by octaprenyl pyrophosphate synthase and its structure-based engineering to produce unprecedented long chain trans-prenyl products Biochemistry, 43, 2004
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6HHQ
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![BU of 6hhq by Molmil](/molmil-images/mine/6hhq) | Crystal structure of compound C45 bound to the yeast 80S ribosome | 分子名称: | (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Pellegrino, S, Vanderwal, C.D, Yusupov, M. | 登録日 | 2018-08-28 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.10000038 Å) | 主引用文献 | Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Res., 47, 2019
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5ON6
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![BU of 5on6 by Molmil](/molmil-images/mine/5on6) | Crystal structure of haemanthamine bound to the 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Pellegrino, S, Meyer, M, Yusupova, G, Yusupov, M. | 登録日 | 2017-08-03 | 公開日 | 2018-02-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.10000229 Å) | 主引用文献 | The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth. Structure, 26, 2018
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6Y11
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![BU of 6y11 by Molmil](/molmil-images/mine/6y11) | Respiratory complex I from Thermus thermophilus | 分子名称: | DUF3197 domain-containing protein, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | 著者 | Gutierrez-Fernandez, J, Minhas, G.S, Sazanov, L.A. | 登録日 | 2020-02-10 | 公開日 | 2020-09-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.109 Å) | 主引用文献 | Key role of quinone in the mechanism of respiratory complex I. Nat Commun, 11, 2020
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3I55
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![BU of 3i55 by Molmil](/molmil-images/mine/3i55) | Co-crystal structure of Mycalamide A Bound to the Large Ribosomal Subunit | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... | 著者 | Gurel, G, Blaha, G, Steitz, T.A, Moore, P.B. | 登録日 | 2009-07-03 | 公開日 | 2010-03-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui. Antimicrob.Agents Chemother., 53, 2009
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4WPB
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![BU of 4wpb by Molmil](/molmil-images/mine/4wpb) | Vascular endothelial growth factor in complex with alpha/beta-VEGF-1 | 分子名称: | Vascular endothelial growth factor A, alpha/beta-VEGF-1 | 著者 | Kreitler, D.F, Checco, J.W, Gellman, S.H, Forest, K.T. | 登録日 | 2014-10-17 | 公開日 | 2015-04-15 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Targeting diverse protein-protein interaction interfaces with alpha / beta-peptides derived from the Z-domain scaffold. Proc.Natl.Acad.Sci.USA, 112, 2015
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7NBU
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![BU of 7nbu by Molmil](/molmil-images/mine/7nbu) | Structure of the HigB1 toxin mutant K95A from Mycobacterium tuberculosis (Rv1955) and its target, the cspA mRNA, on the E. coli Ribosome. | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Giudice, E, Mansour, M, Chat, S, D'Urso, G, Gillet, R, Genevaux, P. | 登録日 | 2021-01-27 | 公開日 | 2022-03-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Substrate recognition and cryo-EM structure of the ribosome-bound TAC toxin of Mycobacterium tuberculosis. Nat Commun, 13, 2022
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7ASO
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8CKU
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![BU of 8cku by Molmil](/molmil-images/mine/8cku) | Translocation intermediate 1 (TI-1*) of 80S S. cerevisiae ribosome with ligands and eEF2 in the absence of sordarin | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | 登録日 | 2023-02-16 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
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6T59
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![BU of 6t59 by Molmil](/molmil-images/mine/6t59) | Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Lin, Z, Gasic, I, Chandrasekaran, V, Peters, N, Shao, S, Ramakrishnan, V, Mitchison, T.J, Hegde, R.S. | 登録日 | 2019-10-15 | 公開日 | 2019-11-27 | 最終更新日 | 2020-01-15 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | TTC5 mediates autoregulation of tubulin via mRNA degradation. Science, 367, 2020
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6OTR
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![BU of 6otr by Molmil](/molmil-images/mine/6otr) | Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (AAU) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Pavelich, I.P, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | 登録日 | 2019-05-03 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
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7BT6
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5IT8
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![BU of 5it8 by Molmil](/molmil-images/mine/5it8) | High-resolution structure of the Escherichia coli ribosome | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | 著者 | Cocozaki, A, Ferguson, A. | 登録日 | 2016-03-16 | 公開日 | 2016-07-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
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8J6K
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![BU of 8j6k by Molmil](/molmil-images/mine/8j6k) | Crystal structure of pro-interleukin-18 and caspase-4 complex | 分子名称: | Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ... | 著者 | Sun, Q, Hou, Y.J, Ding, J. | 登録日 | 2023-04-26 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome. Nature, 624, 2023
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6LU8
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![BU of 6lu8 by Molmil](/molmil-images/mine/6lu8) | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | 登録日 | 2020-01-26 | 公開日 | 2020-08-26 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
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6LSR
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![BU of 6lsr by Molmil](/molmil-images/mine/6lsr) | Cryo-EM structure of a pre-60S ribosomal subunit - state B | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | 登録日 | 2020-01-20 | 公開日 | 2020-08-26 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
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7NWI
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![BU of 7nwi by Molmil](/molmil-images/mine/7nwi) | Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA+BlaS, 40S ribosomal protein S11, ... | 著者 | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | 登録日 | 2021-03-16 | 公開日 | 2021-07-07 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
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7BV8
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![BU of 7bv8 by Molmil](/molmil-images/mine/7bv8) | Mature 50S ribosomal subunit from RrmJ knock out E.coli strain | 分子名称: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | 著者 | Wang, W, Li, W.Q, Ge, X.L, Yan, K.G, Mandava, C.S, Sanyal, S, Gao, N. | 登録日 | 2020-04-09 | 公開日 | 2020-07-01 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation. Proc.Natl.Acad.Sci.USA, 117, 2020
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6CZR
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![BU of 6czr by Molmil](/molmil-images/mine/6czr) | The structure of amicetin bound to the 70S ribosome | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Eiler, D.R, Steitz, T.A, Looper, R.E, Serrano, C.M, Kannareddy, H.R, Koch, M.R, Barrows, L.R, Testa, C.A, Sebahar, P.R. | 登録日 | 2018-04-09 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | Unifying the Aminohexopyranose- and Peptidyl-Nucleoside Antibiotics: Implications for Antibiotic Design Angew.Chem.Int.Ed.Engl., 132, 2020
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