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6TTM
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Hyoscyamine 6-hydroxylase in complex with N-oxalylglycine and hyoscyamine
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Hyoscyamine 6 beta-hydroxylase, ...
著者Kluza, A, Kurpiewska, K, Mrugala, B, Porebski, P.J, Niedzialkowska, E, Minor, W, Borowski, T.
登録日2019-12-29
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Regioselectivity of hyoscyamine 6 beta-hydroxylase-catalysed hydroxylation as revealed by high-resolution structural information and QM/MM calculations.
Dalton Trans, 49, 2020
1UXR
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Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax
分子名称: 6-O-phosphono-beta-D-fructofuranose, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Lorentzen, E, Hensel, R, Pohl, E.
登録日2004-03-01
公開日2004-08-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax
J.Mol.Biol., 341, 2004
6TTN
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N-terminally truncated hyoscyamine 6-hydroxylase (tH6H) in complex with N-oxalylglycine and hyoscyamine
分子名称: 1,2-ETHANEDIOL, Hyoscyamine 6 beta-hydroxylase, N-OXALYLGLYCINE, ...
著者Kluza, A, Mrugala, B, Porebski, P.J, Kurpiewska, K, Niedzialkowska, E, Weiss, M.S, Borowski, T.
登録日2019-12-29
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Regioselectivity of hyoscyamine 6 beta-hydroxylase-catalysed hydroxylation as revealed by high-resolution structural information and QM/MM calculations.
Dalton Trans, 49, 2020
5CZM
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Crystal structure of a mutated catalytic domain of Human MMP12 in complex with RXP470
分子名称: CALCIUM ION, Macrophage metalloelastase, N-[(2S)-3-[(S)-(4-bromophenyl)(hydroxy)phosphoryl]-2-{[3-(3'-chlorobiphenyl-4-yl)-1,2-oxazol-5-yl]methyl}propanoyl]-L-alpha-glutamyl-L-alpha-glutamine, ...
著者Rouanet-Mehouas, C, Roselia, L, Devel, L, Dive, V, Stura, E.A.
登録日2015-07-31
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.303 Å)
主引用文献Zinc-Metalloproteinase Inhibitors: Evaluation of the Complex Role Played by the Zinc-Binding Group on Potency and Selectivity.
J. Med. Chem., 60, 2017
1KBV
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NITRITE-SOAKED CRYSTAL STRUCTURE OF THE SOLUBLE DOMAIN OF ANIA FROM NEISSERIA GONORRHOEAE
分子名称: COPPER (II) ION, Major outer membrane protein PAN 1, NITRITE ION
著者Boulanger, M.J, Murphy, M.E.P.
登録日2001-11-06
公開日2001-12-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the soluble domain of the major anaerobically induced outer membrane protein (AniA) from pathogenic Neisseria: a new class of copper-containing nitrite reductases.
J.Mol.Biol., 315, 2002
6TR4
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Ruminococcus gnavus GH29 fucosidase E1_10125 D221A mutant in complex with fucose
分子名称: CALCIUM ION, CHLORIDE ION, F5/8 type C domain-containing protein, ...
著者Owen, C.D, Wu, H, Crost, E, Colvile, A, Juge, N, Walsh, M.A.
登録日2019-12-17
公開日2020-10-28
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Fucosidases from the human gut symbiont Ruminococcus gnavus.
Cell.Mol.Life Sci., 78, 2021
3HWS
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Crystal structure of nucleotide-bound hexameric ClpX
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit clpX, MAGNESIUM ION, ...
著者Glynn, S.E, Martin, A, Baker, T.A, Sauer, R.T.
登録日2009-06-18
公開日2009-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine.
Cell(Cambridge,Mass.), 139, 2009
1KQN
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Crystal structure of NMN/NaMN adenylyltransferase complexed with NAD
分子名称: NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, XENON
著者Zhou, T, Kurnasov, O, Tomchick, D.R, Binns, D.D, Grishin, N.V, Marquez, V.E, Osterman, A.L, Zhang, H.
登録日2002-01-07
公開日2003-01-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Human Nicotinamide/Nicotonic Acid Mononucleotide Adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin.
J.Biol.Chem., 277, 2003
1NDO
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NAPHTHALENE 1,2-DIOXYGENASE
分子名称: FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, NAPHTHALENE 1,2-DIOXYGENASE
著者Ramaswamy, S, Kauppi, B, Carredano, E.
登録日1998-01-11
公開日1999-03-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of an aromatic-ring-hydroxylating dioxygenase-naphthalene 1,2-dioxygenase.
Structure, 6, 1998
1HWK
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COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH ATORVASTATIN
分子名称: 7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]- 3,5-DIHYDROXY-HEPTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE
著者Istvan, E.S, Deisenhofer, J.
登録日2001-01-09
公開日2001-05-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural mechanism for statin inhibition of HMG-CoA reductase.
Science, 292, 2001
8BFT
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The E. coli TrpD2 protein YbiB in complex with a C-terminal peptide from ObgE
分子名称: DI(HYDROXYETHYL)ETHER, GTPase ObgE/CgtA, Protein YbiB
著者Deckers, B, Galicia, C, Versees, W.
登録日2022-10-26
公開日2023-02-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献YbiB: a novel interactor of the GTPase ObgE.
Nucleic Acids Res., 51, 2023
5W19
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Tryptophan indole-lyase complex with oxindolyl-L-alanine
分子名称: 1-carboxy-1-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]azaniumyl}-2-[(3R)-2-oxo-2,3-dihydro-1H-indol-3-yl]ethan-1-ide, POTASSIUM ION, Tryptophanase
著者Phillips, R.S, Wood, Z.A.
登録日2017-06-02
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of Proteus vulgaris tryptophan indole-lyase complexed with oxindolyl-L-alanine: implications for the reaction mechanism.
Acta Crystallogr D Struct Biol, 74, 2018
5VOT
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BU of 5vot by Molmil
Structure of AMPA receptor-TARP complex
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
著者Chen, S, Zhao, Y, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E.
登録日2017-05-03
公開日2017-07-12
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
8OR4
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Partially dissociated CAND1-CUL1-RBX1-SKP1-SKP2-CKS1-CDK2
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, Cyclin-dependent kinase 2, ...
著者Shaaban, M, Clapperton, J.A, Ding, S, Maeots, M.E, Enchev, R.I.
登録日2023-04-13
公開日2023-06-28
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange.
Mol.Cell, 83, 2023
8OR3
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CAND1-CUL1-RBX1-SKP1-SKP2-DCNL1
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, DCN1-like protein 1, ...
著者Shaaban, M, Clapperton, J.A, Ding, S, Maeots, M.E, Enchev, R.I.
登録日2023-04-13
公開日2023-06-28
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange.
Mol.Cell, 83, 2023
6CHM
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Phosphopantetheine adenylyltransferase (CoaD) in complex with N-(2-(5-methoxy-1H-indol-3-yl)ethyl)pivalamide
分子名称: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2,2-dimethylpropanamide, Phosphopantetheine adenylyltransferase, SULFATE ION
著者Mamo, M, Appleton, B.A.
登録日2018-02-22
公開日2018-04-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity.
J. Med. Chem., 61, 2018
8OR0
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CAND1-CUL1-RBX1-SKP1-SKP2-CKS1-CDK2
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, Cyclin-dependent kinase 2, ...
著者Shaaban, M, Clapperton, J.A, Ding, S, Maeots, M.E, Enchev, R.I.
登録日2023-04-12
公開日2023-06-28
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange.
Mol.Cell, 83, 2023
8OR2
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CAND1-CUL1-RBX1-DCNL1
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, DCN1-like protein 1, ...
著者Shaaban, M, Clapperton, J.A, Ding, S, Maeots, M.E, Enchev, R.I.
登録日2023-04-12
公開日2023-06-28
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange.
Mol.Cell, 83, 2023
8PAZ
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OXIDIZED NATIVE PSEUDOAZURIN FROM A. FAECALIS
分子名称: COPPER (II) ION, PSEUDOAZURIN
著者Adman, E.T, Libeu, C.A.P.
登録日1997-02-24
公開日1997-08-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Site-directed mutants of pseudoazurin: explanation of increased redox potentials from X-ray structures and from calculation of redox potential differences.
Biochemistry, 36, 1997
8BIG
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BU of 8big by Molmil
O-Methyltransferase Plu4895 in complex with SAH
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2022-11-02
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A set of closely related methyltransferases for site-specific tailoring of anthraquinone pigments.
Structure, 31, 2023
6E9V
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DHF79 filament
分子名称: DHF79 filament
著者Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D.
登録日2018-08-01
公開日2018-11-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献De novo design of self-assembling helical protein filaments.
Science, 362, 2018
2CW0
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BU of 2cw0 by Molmil
Crystal structure of Thermus thermophilus RNA polymerase holoenzyme at 3.3 angstroms resolution
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark Jr, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E.
登録日2005-06-15
公開日2005-09-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation
Cell(Cambridge,Mass.), 122, 2005
1UXT
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Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax
分子名称: 1-O-phosphono-alpha-D-glucopyranose, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Lorentzen, E, Hensel, R, Pohl, E.
登録日2004-03-01
公開日2004-08-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax
J.Mol.Biol., 341, 2004
8OUC
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Escherichia coli DPS
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA protection during starvation protein
著者Kovalenko, V.V, Loiko, N.G, Tereshkina, K.B, Tereshkin, E.V, Chulichkov, A.L, Popov, A.N, Krupyanskii, Y.F.
登録日2023-04-22
公開日2023-05-03
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Escherichia coli DPS
To be published
1NFD
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AN ALPHA-BETA T CELL RECEPTOR (TCR) HETERODIMER IN COMPLEX WITH AN ANTI-TCR FAB FRAGMENT DERIVED FROM A MITOGENIC ANTIBODY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, H57 FAB, N15 ALPHA-BETA T-CELL RECEPTOR
著者Wang, J.-H, Lim, K, Smolyar, A, Teng, M.-K, Sacchittini, J, Reinherz, E.L.
登録日1997-08-04
公開日1998-01-28
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody.
EMBO J., 17, 1998

223790

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