4FIV
| FIV PROTEASE COMPLEXED WITH AN INHIBITOR LP-130 | 分子名称: | 4-[2-(2-ACETYLAMINO-3-NAPHTALEN-1-YL-PROPIONYLAMINO)-4-METHYL-PENTANOYLAMINO]-3-HYDROXY-6-METHYL-HEPTANOIC ACID [1-(1-CARBAMOYL-2-NAPHTHALEN-1-YL-ETHYLCARBAMOYL)-PROPYL]-AMIDE, FELINE IMMUNODEFICIENCY VIRUS PROTEASE | 著者 | Kervinen, J, Lubkowski, J, Zdanov, A, Wlodawer, A, Gustchina, A. | 登録日 | 1998-07-15 | 公開日 | 1999-01-13 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV. Protein Sci., 7, 1998
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7MOQ
| The structure of the Tetrahymena thermophila outer dynein arm on doublet microtubule | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Docking complex 1 protein, ... | 著者 | Kubo, S, Yang, S.K, Ichikawa, M, Bui, K.H. | 登録日 | 2021-05-03 | 公開日 | 2021-07-14 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-EM. Embo Rep., 22, 2021
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3SGA
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6ZX9
| Crystal structure of SIV Vpr,fused to T4 lysozyme, isolated from moustached monkey, bound to human DDB1 and human DCAF1 (amino acid residues 1046-1396) | 分子名称: | DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1, GLYCEROL, ... | 著者 | Schwefel, D, Banchenko, S. | 登録日 | 2020-07-29 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.519729 Å) | 主引用文献 | Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses. Plos Pathog., 17, 2021
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2C7Y
| plant enzyme | 分子名称: | 3-KETOACYL-COA THIOLASE 2 | 著者 | Sundaramoorthy, R, Micossi, E, Alphey, M.S, Germain, V, Bryce, J.H, Smith, S.M, Leonard, G.A, Hunter, W.N. | 登録日 | 2005-11-30 | 公開日 | 2006-05-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Crystal Structure of a Plant 3-Ketoacyl-Coa Thiolase Reveals the Potential for Redox Control of Peroxisomal Fatty Acid Beta-Oxidation. J.Mol.Biol., 359, 2006
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7PU1
| High resolution X-ray structure of Thermoascus aurantiacus LPMO | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, COPPER (II) ION, ... | 著者 | Banerjee, S, Frandsen, K.E.H, Singh, R.K, Bjerrum, M.J, Lo Leggio, L. | 登録日 | 2021-09-28 | 公開日 | 2022-03-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | Protonation State of an Important Histidine from High Resolution Structures of Lytic Polysaccharide Monooxygenases. Biomolecules, 12, 2022
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3C2K
| DNA POLYMERASE BETA with a gapped DNA substrate and DUMPNPP with Manganese in the active site | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*DCP*DCP*DGP*DAP*DCP*DAP*DGP*DCP*DGP*DCP*DAP*DTP*DCP*DAP*DGP*DC)-3'), ... | 著者 | Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H. | 登録日 | 2008-01-25 | 公開日 | 2008-05-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of DNA polymerase beta with active-site mismatches suggest a transient abasic site intermediate during misincorporation. Mol.Cell, 30, 2008
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6ZZ4
| Crystal structure of the PTPN2 C216G mutant | 分子名称: | PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 2 | 著者 | Mechaly, A.E, Berthelet, J, Nian, Q, Parlato, M, Cerf-Bensussan, N, Haouz, A, Rodrigues-Lima, F. | 登録日 | 2020-08-03 | 公開日 | 2021-08-18 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy. Protein Sci., 31, 2022
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7A0H
| Structure of homodimeric actin capping protein alpha subunit from Plasmodium berghei | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BROMIDE ION, F-actin-capping protein subunit alpha, ... | 著者 | Bendes, A.A, Kursula, P, Kursula, I. | 登録日 | 2020-08-09 | 公開日 | 2021-08-18 | 最終更新日 | 2022-02-23 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structure and function of an atypical homodimeric actin capping protein from the malaria parasite. Cell.Mol.Life Sci., 79, 2022
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3THI
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4TN4
| Crystal structure of ternary complex of Plasmodium vivax SHMT with glycine and a novel pyrazolopyran 33G: (4S)-6-amino-4-(5-cyano-3'-fluorobiphenyl-3-yl)-4-cyclobutyl-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | 分子名称: | (4S)-6-amino-4-(5-cyano-3'-fluorobiphenyl-3-yl)-4-cyclobutyl-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | 著者 | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U, Witschel, M.C. | 登録日 | 2014-06-03 | 公開日 | 2015-03-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT): Cocrystal Structures of Pyrazolopyrans with Potent Blood- and Liver-Stage Activities. J.Med.Chem., 58, 2015
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6ZIK
| bovine ATP synthase rotor domain, state 3 | 分子名称: | ATP synthase F(0) complex subunit C2, mitochondrial, ATP synthase subunit delta, ... | 著者 | Spikes, T, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-06-26 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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7U53
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4IVT
| Crystal structure of BACE1 with its inhibitor | 分子名称: | Beta-secretase 1, N-{N-[4-(acetylamino)-3,5-dichlorobenzyl]carbamimidoyl}-2-(1H-indol-1-yl)acetamide, SULFATE ION | 著者 | Chen, T.T, Li, L, Chen, W.Y, Xu, Y.C. | 登録日 | 2013-01-23 | 公開日 | 2013-11-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Virtual screening and structure-based discovery of indole acylguanidines as potent beta-secretase (BACE1) inhibitors Molecules, 18, 2013
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2ZM5
| Crystal structure of tRNA modification enzyme MiaA in the complex with tRNA(Phe) | 分子名称: | MAGNESIUM ION, tRNA delta(2)-isopentenylpyrophosphate transferase, tRNA(Phe) | 著者 | Sakai, J, Yao, M, Chimnaronk, S, Tanaka, I. | 登録日 | 2008-04-11 | 公開日 | 2009-04-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon Biochemistry, 48, 2009
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3TJ3
| Structure of importin a5 bound to the N-terminus of Nup50 | 分子名称: | Importin subunit alpha-1, Nuclear pore complex protein Nup50 | 著者 | Pumroy, R, Nardozzi, J.D, Hart, D.J, Root, M.J, Cingolani, G. | 登録日 | 2011-08-23 | 公開日 | 2011-11-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | 主引用文献 | Nucleoporin Nup50 stabilizes closed conformation of armadillo repeat 10 in importin alpha 5. J.Biol.Chem., 287, 2012
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8IF2
| Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron BQ.1.1 variant spike protein in complex with its receptor ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Kimura, K, Suzuki, T, Hashiguchi, T. | 登録日 | 2023-02-17 | 公開日 | 2023-05-17 | 最終更新日 | 2023-05-24 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Convergent evolution of SARS-CoV-2 Omicron subvariants leading to the emergence of BQ.1.1 variant. Nat Commun, 14, 2023
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7NFX
| Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Jomaa, A, Lee, J.H, Shan, S, Ban, N. | 登録日 | 2021-02-08 | 公開日 | 2021-06-02 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER. Sci Adv, 7, 2021
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4IVS
| Crystal structure of BACE1 with its inhibitor | 分子名称: | Beta-secretase 1, N-{N-[4-(acetylamino)-3,5-dichlorobenzyl]carbamimidoyl}-2-(6-cyano-1H-indol-1-yl)acetamide | 著者 | Chen, T.T, Li, L, Chen, W.Y, Xu, Y.C. | 登録日 | 2013-01-23 | 公開日 | 2013-11-13 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.636 Å) | 主引用文献 | Virtual screening and structure-based discovery of indole acylguanidines as potent beta-secretase (BACE1) inhibitors Molecules, 18, 2013
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7A5C
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7A5Q
| Crystal structure of VcSiaP bound to sialic acid | 分子名称: | DctP family TRAP transporter solute-binding subunit, GLYCEROL, N-acetyl-beta-neuraminic acid, ... | 著者 | Schneberger, N, Peter, M.F, Hagelueken, G. | 登録日 | 2020-08-21 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Triggering Closure of a Sialic Acid TRAP Transporter Substrate Binding Protein through Binding of Natural or Artificial Substrates. J.Mol.Biol., 433, 2020
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7A4N
| Cryo-EM structure of a prefusion stabilized SARS-CoV-2 Spike (D614N, R682S, R685G, A892P, A942P and V987P)(S-closed trimer) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin | 著者 | Rutten, L, Renault, L.L.R, Juraszek, J, Langedijk, J.P.M. | 登録日 | 2020-08-20 | 公開日 | 2020-11-04 | 最終更新日 | 2021-01-27 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Stabilizing the closed SARS-CoV-2 spike trimer. Nat Commun, 12, 2021
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3QFD
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6ZG8
| bovine ATP synthase rotor domain state 2 | 分子名称: | ATP synthase F(0) complex subunit C2, mitochondrial, ATP synthase subunit delta, ... | 著者 | Spikes, T, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-06-18 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6SGC
| Rabbit 80S ribosome stalled on a poly(A) tail | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Chandrasekaran, V, Juszkiewicz, S, Choi, J, Puglisi, J.D, Brown, A, Shao, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2019-08-03 | 公開日 | 2019-12-04 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of ribosome stalling during translation of a poly(A) tail. Nat.Struct.Mol.Biol., 26, 2019
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