3QFD

Human Class I MHC HLA-A2 in complex with Mart-1(27-35) nonameric peptide

Summary for 3QFD

Entry DOI	10.2210/pdb3qfd/pdb
Related	2GUO
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Mart-1(27-35) peptide, ... (6 entities in total)
Functional Keywords	mart-1 peptide, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, melanoma, immune system
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769
Total number of polymer chains	6
Total formula weight	89693.63
Authors	Borbulevych, O.Y.,Baker, B.M. (deposition date: 2011-01-21, release date: 2011-09-28, Last modification date: 2011-12-14)
Primary citation	Insaidoo, F.K.,Borbulevych, O.Y.,Hossain, M.,Santhanagopolan, S.M.,Baxter, T.K.,Baker, B.M. Loss of T Cell Antigen Recognition Arising from Changes in Peptide and Major Histocompatibility Complex Protein Flexibility: IMPLICATIONS FOR VACCINE DESIGN. J.Biol.Chem., 286:40163-40173, 2011 Cited by PubMed: 21937447 DOI: 10.1074/jbc.M111.283564 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.68 Å)

Structure validation