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3HQH
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Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep1
分子名称: MacroH2A, Speckle-type POZ protein, ZINC ION
著者Zhuang, M, Schulman, B.A.
登録日2009-06-06
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HU3
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Structure of p97 N-D1 R155H mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Tang, W.-K.
登録日2009-06-12
公開日2010-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants.
Embo J., 29, 2010
3I7P
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Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR40A
分子名称: DNA damage-binding protein 1, WD repeat-containing protein 40A
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7O
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Crystal Structure of DDB1 in Complex with the H-Box Motif of IQWD1
分子名称: DNA damage-binding protein 1, IQ motif and WD repeat-containing protein 1
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3IHI
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Crystal structure of mouse thymidylate synthase
分子名称: SULFATE ION, Thymidylate synthase
著者Dowiercial, A, Jarmula, A, Rypniewski, W.R, Sokolowska, M, Fraczyk, T, Ciesla, J, Rode, W.
登録日2009-07-30
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme
Struct Chem, 2016
3I7N
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Crystal Structure of DDB1 in Complex with the H-Box Motif of WDTC1
分子名称: DNA damage-binding protein 1, WD and tetratricopeptide repeats protein 1
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7H
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Crystal Structure of DDB1 in Complex with the H-Box Motif of HBX
分子名称: DNA damage-binding protein 1, X protein
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3IUC
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Crystal structure of the human 70kDa heat shock protein 5 (BiP/GRP78) ATPase domain in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Heat shock 70kDa protein 5 (Glucose-regulated protein, ...
著者Wisniewska, M, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日2009-08-31
公開日2009-09-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Plos One, 5, 2010
3I7L
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Crystal Structure of DDB1 in Complex with the H-Box Motif of DDB2
分子名称: DNA damage-binding protein 1, DNA damage-binding protein 2
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3IU5
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Crystal structure of the first bromodomain of human poly-bromodomain containing protein 1 (PB1)
分子名称: Protein polybromo-1
著者Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2009-08-30
公開日2009-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3I7K
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BU of 3i7k by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WHX
分子名称: DNA damage-binding protein 1, X protein
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-08
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I8E
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BU of 3i8e by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR42A
分子名称: DNA damage-binding protein 1, WD repeat-containing protein 42A
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-09
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I89
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Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR22
分子名称: DNA damage-binding protein 1, WD repeat-containing protein 22
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-09
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3IJ1
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BU of 3ij1 by Molmil
Crystal structure of Eed in complex with a trimethylated histone H4K20 peptide
分子名称: Histone H4K20 peptide, Polycomb protein EED
著者Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J.
登録日2009-08-03
公開日2009-09-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
3I8C
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BU of 3i8c by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR21A
分子名称: DNA damage-binding protein 1, WD repeat-containing protein 21A
著者Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
登録日2009-07-09
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3IVB
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BU of 3ivb by Molmil
Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-MacroH2ASBCpep1
分子名称: CHLORIDE ION, Core histone macro-H2A.1, Speckle-type POZ protein, ...
著者Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
登録日2009-08-31
公開日2009-10-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure 9
To be Published
3J0S
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BU of 3j0s by Molmil
Remodeling of actin filaments by ADF cofilin proteins
分子名称: Actin, cytoplasmic 1, Cofilin-2
著者Galkin, V.E, Orlova, A, Kudryashov, D.S, Solodukhin, A, Reisler, E, Schroeder, G.F, Egelman, E.H.
登録日2011-11-24
公開日2011-12-21
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Remodeling of actin filaments by ADF/cofilin proteins.
Proc.Natl.Acad.Sci.USA, 108, 2011
3IXS
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Ring1B C-terminal domain/RYBP C-terminal domain Complex
分子名称: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, E3 ubiquitin-protein ligase RING2, ...
著者Wang, R, Taylor, A.B, Kim, C.A.
登録日2009-09-04
公開日2010-08-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Polycomb Group Targeting through Different Binding Partners of RING1B C-Terminal Domain.
Structure, 18, 2010
3K6P
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Estrogen Related Receptor alpha in Complex with an Ether Based Ligand
分子名称: 4-(4-{[(5R)-2,4-dioxo-1,3-thiazolidin-5-yl]methyl}-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile, Steroid hormone receptor ERR1
著者Abad, M.C, Patch, R.J.
登録日2009-10-09
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Development of Diaryl Ether based ligands for Estrogen Related Receptor alpha as Potential Anti-Diabetic Agents.
To be Published
3J7R
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BU of 3j7r by Molmil
Structure of the translating mammalian ribosome-Sec61 complex
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
登録日2014-08-01
公開日2014-09-03
最終更新日2019-10-30
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3KFC
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Complex Structure of LXR with an agonist
分子名称: 4-{3-[3-(methylsulfonyl)phenoxy]phenyl}-8-(trifluoromethyl)quinoline, Oxysterols receptor LXR-beta
著者Olland, A, Bernotas, R.C, Unwalla, R.
登録日2009-10-27
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献4-(3-Aryloxyaryl)quinoline sulfones are potent liver X receptor agonists.
Bioorg.Med.Chem.Lett., 20, 2010
3KB7
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Crystal structure of Polo-like kinase 1 in complex with a pyrazoloquinazoline inhibitor
分子名称: 8-{[2-methoxy-5-(4-methylpiperazin-1-yl)phenyl]amino}-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide, L(+)-TARTARIC ACID, Serine/threonine-protein kinase PLK1, ...
著者Bossi, R.T, Bertrand, J.A.
登録日2009-10-20
公開日2010-05-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors
J.Med.Chem., 53, 2010
3J5Y
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Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP
分子名称: 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ...
著者des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2013-11-21
公開日2013-12-25
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP.
Nucleic Acids Res., 42, 2014
3J7P
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Structure of the 80S mammalian ribosome bound to eEF2
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
登録日2014-08-01
公開日2014-09-03
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3JSX
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X-ray Crystal structure of NAD(P)H: Quinone Oxidoreductase-1 (NQO1) bound to the coumarin-based inhibitor AS1
分子名称: 4-hydroxy-6,7-dimethyl-3-(naphthalen-1-ylmethyl)-2H-chromen-2-one, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1
著者Dunstan, M.S, Levy, C, Leys, D.
登録日2009-09-11
公開日2010-01-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Synthesis and biological evaluation of coumarin-based inhibitors of NAD(P)H: quinone oxidoreductase-1 (NQO1).
J.Med.Chem., 52, 2009

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