3IHI

Crystal structure of mouse thymidylate synthase

Summary for 3IHI

• Entry DOI: 10.2210/pdb3ihi/pdb
• Related: 3IHH
• Descriptor: Thymidylate synthase, SULFATE ION (3 entities in total)
• Functional Keywords: protein-ligand complex, methyltransferase, nucleotide biosynthesis, transferase
• Biological source: Mus musculus (mouse)
• Cellular location: Nucleus : P07607
• Total number of polymer chains: 2
• Total formula weight: 70194.16

Authors

Dowiercial, A.,Jarmula, A.,Rypniewski, W.R.,Sokolowska, M.,Fraczyk, T.,Ciesla, J.,Rode, W. (deposition date: 2009-07-30, release date: 2010-02-02, Last modification date: 2023-09-06)

• Primary citation: Dowiercial, A.,Jarmula, A.,Wilk, P.,Rypniewski, W.,Kowalska, M.,Fraczyk, T.,Ciesla, J.,Rode, W.; Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme; Struct Chem, 2016; DOI: 10.1007/s11224-016-0840-8

Experimental method

X-RAY DIFFRACTION (1.94 Å)