3K6P

Estrogen Related Receptor alpha in Complex with an Ether Based Ligand

Summary for 3K6P

• Entry DOI: 10.2210/pdb3k6p/pdb
• Descriptor: Steroid hormone receptor ERR1, 4-(4-{[(5R)-2,4-dioxo-1,3-thiazolidin-5-yl]methyl}-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile (3 entities in total)
• Functional Keywords: estrogen related receptor alpha, dna-binding, isopeptide bond, metal-binding, nucleus, phosphoprotein, receptor, transcription, transcription regulation, zinc-finger, hormone receptor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 27586.74

Authors

Abad, M.C.,Patch, R.J. (deposition date: 2009-10-09, release date: 2010-10-20, Last modification date: 2023-09-06)

• Primary citation: Patch, R.J.,Searle, L.L.,Kim, A.J.,De, D.,Zhu, X.,Askari, H.B.,O'Neill, J.C.,Abad, M.C.,Rentzeperis, D.,Geisler, J.G.; Development of Diaryl Ether based ligands for Estrogen Related Receptor alpha as Potential Anti-Diabetic Agents.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.996 Å)