PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

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4WOI	4,5-linked aminoglycoside antibiotics regulate the bacterial ribosome by targeting dynamic conformational processes within intersubunit bridge B2 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Pulk, A, Cate, J.H.D, Blanchard, S, Wasserman, M, Altman, R, Zhou, Z, Zinder, J, Green, K, Garneau-Tsodikova, S. 登録日 2014-10-15 公開日 2015-08-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions. Nat Commun, 6, 2015
7TOO	Yeast 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. 登録日 2022-01-24 公開日 2022-05-25 最終更新日 2022-06-01 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
4WF1	Crystal structure of the E. coli ribosome bound to negamycin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C. 登録日 2014-09-11 公開日 2014-11-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome. Proc.Natl.Acad.Sci.USA, 111, 2014
4WWW	Crystal structure of the E. coli ribosome bound to CEM-101 分子名称: (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S rRNA, 23S rRNA, ... 著者 Dunkle, J.A, Zhang, W, Cate, J.H.D, Mankin, A.S. 登録日 2014-11-12 公開日 2014-12-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis. Antimicrob. Agents Chemother., 54, 2010
4WT8	Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex 分子名称: 23S rRNA (2899-MER), 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Amunts, A, Fiedorczuk, K, Ramakrishnan, V. 登録日 2014-10-29 公開日 2015-01-21 最終更新日 2018-07-18 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics. J.Mol.Biol., 427, 2015
7U0H	State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model 分子名称: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... 著者 Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. 登録日 2022-02-18 公開日 2022-12-14 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
4WZD	Complex of 70S ribosome with cognate tRNA-Tyr in the P-site 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2014-11-19 公開日 2015-06-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
4V4X	Crystal structure of the 70S Thermus thermophilus ribosome showing how the 16S 3'-end mimicks mRNA E and P codons. 分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Jenner, L, Yusupova, G, Rees, B, Moras, D, Yusupov, M. 登録日 2006-06-27 公開日 2014-07-09 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (5 Å) 主引用文献 Structural basis for messenger RNA movement on the ribosome. Nature, 444, 2006
4V5B	Structure of PDF binding helix in complex with the ribosome. 分子名称: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Bingel-Erlenmeyer, R, Kohler, R, Kramer, G, Sandikci, A, Antolic, S, Maier, T, Schaffitzel, C, Wiedmann, B, Bukau, B, Ban, N. 登録日 2007-11-22 公開日 2014-07-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.74 Å) 主引用文献 A Peptide Deformylase-Ribosome Complex Reveals Mechanism of Nascent Chain Processing. Nature, 452, 2008
4V6S	Structural characterization of mRNA-tRNA translocation intermediates (class 3 of the six classes) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. 登録日 2011-12-09 公開日 2014-07-09 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (13.1 Å) 主引用文献 Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
4V69	Ternary complex-bound E.coli 70S ribosome. 分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Villa, E, Sengupta, J, Trabuco, L.G, LeBarron, J, Baxter, W.T, Shaikh, T.R, Grassucci, R.A, Nissen, P, Ehrenberg, M, Schulten, K, Frank, J. 登録日 2008-12-11 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis Proc.Natl.Acad.Sci.USA, 106, 2009
4V6O	Structural characterization of mRNA-tRNA translocation intermediates (class 4a of the six classes) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. 登録日 2011-12-07 公開日 2014-07-09 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (14.7 Å) 主引用文献 Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
4V70	E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre3) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. 登録日 2013-10-14 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (17 Å) 主引用文献 Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
4V6I	Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces cerevisiae translating 80S ribosome 分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein RACK1 (RACK1), ... 著者 Armache, J.-P, Jarasch, A, Anger, A.M, Villa, E, Becker, T, Bhushan, S, Jossinet, F, Habeck, M, Dindar, G, Franckenberg, S, Marquez, V, Mielke, T, Thomm, M, Berninghausen, O, Beatrix, B, Soeding, J, Westhof, E, Wilson, D.N, Beckmann, R. 登録日 2010-10-12 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (8.8 Å) 主引用文献 Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution. Proc.Natl.Acad.Sci.USA, 107, 2010
4V6Z	E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1b) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. 登録日 2013-10-14 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (12 Å) 主引用文献 Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
4V7D	Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA*EF-G structure) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Brilot, A.F, Korostelev, A.A, Ermolenko, D.N, Grigorieff, N. 登録日 2013-11-21 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Structure of the ribosome with elongation factor G trapped in the pretranslocation state. Proc.Natl.Acad.Sci.USA, 110, 2013
4V6Y	E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1a) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. 登録日 2013-10-14 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (12 Å) 主引用文献 Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
4V7U	Crystal structure of the E. coli ribosome bound to erythromycin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. 登録日 2010-08-15 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010
4V7C	Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA structure) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Brilot, A.F, Korostelev, A.A, Ermolenko, D.N, Grigorieff, N. 登録日 2013-11-20 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Structure of the ribosome with elongation factor G trapped in the pretranslocation state. Proc.Natl.Acad.Sci.USA, 110, 2013
4V8X	Structure of Thermus thermophilus ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Feng, S, Chen, Y, Kamada, K, Wang, H, Tang, K, Wang, M, Gao, Y.G. 登録日 2013-07-19 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Yoeb-Ribosome Structure: A Canonical Rnase that Requires the Ribosome for its Specific Activity. Nucleic Acids Res., 41, 2013
4V9L	70S Ribosome translocation intermediate FA-3.6A containing elongation factor EFG/FUSIDIC ACID/GDP, mRNA, and tRNA bound in the pe*/E state. 分子名称: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F. 登録日 2013-04-24 公開日 2014-07-09 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation. Science, 340, 2013
8JIV	Atomic structure of wheat ribosome reveals unique features of the plant ribosomes 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Mishra, R.K, Sharma, P, Hussain, T. 登録日 2023-05-28 公開日 2024-03-27 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.84 Å) 主引用文献 Cryo-EM structure of wheat ribosome reveals unique features of the plant ribosomes. Structure, 32, 2024
4V4S	Crystal structure of the whole ribosomal complex. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V. 登録日 2005-10-12 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (6.76 Å) 主引用文献 Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon. Cell(Cambridge,Mass.), 123, 2005
4V56	Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D. 登録日 2007-07-21 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.93 Å) 主引用文献 A steric block in translation caused by the antibiotic spectinomycin. Acs Chem.Biol., 2, 2007
4V65	Structure of the E. coli ribosome in the Pre-accommodation state 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Devkota, B, Caulfield, T.R, Tan, R.-Z, Harvey, S.C. 登録日 2008-08-03 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 The Structure of the E. coli Ribosome Before and After Accommodation: Implications for Proofreading To be Published

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