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5FWM
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BU of 5fwm by Molmil
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日2016-02-18
公開日2016-07-06
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase.
Science, 352, 2016
3DLA
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BU of 3dla by Molmil
X-ray crystal structure of glutamine-dependent NAD+ synthetase from Mycobacterium tuberculosis bound to NaAD+ and DON
分子名称: 5-OXO-L-NORLEUCINE, GLYCEROL, Glutamine-dependent NAD(+) synthetase, ...
著者LaRonde-LeBlanc, N.A, Resto, M, Gerratana, B.
登録日2008-06-26
公開日2009-03-10
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Regulation of active site coupling in glutamine-dependent NAD(+) synthetase.
Nat.Struct.Mol.Biol., 16, 2009
5AVM
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BU of 5avm by Molmil
Crystal structures of 5-aminoimidazole ribonucleotide (AIR) synthetase, PurM, from Thermus thermophilus
分子名称: Phosphoribosylformylglycinamidine cyclo-ligase, SULFATE ION
著者Kanagawa, M, Baba, S, Watanabe, Y, Nakagawa, N, Ebihara, A, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2015-06-23
公開日2015-11-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures and ligand binding of PurM proteins from Thermus thermophilus and Geobacillus kaustophilus
J.Biochem., 159, 2016
7ZR0
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BU of 7zr0 by Molmil
CryoEM structure of HSP90-CDC37-BRAF(V600E) complex.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
著者Oberoi, J, Pearl, L.H.
登録日2022-05-03
公開日2022-12-14
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.
Nat Commun, 13, 2022
7ZR5
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BU of 7zr5 by Molmil
CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(closed) complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
著者Oberoi, J, Pearl, L.H.
登録日2022-05-03
公開日2022-12-14
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.
Nat Commun, 13, 2022
7ZR6
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BU of 7zr6 by Molmil
CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
著者Oberoi, J, Pearl, L.H.
登録日2022-05-03
公開日2022-12-28
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.
Nat Commun, 13, 2022
6G2H
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BU of 6g2h by Molmil
Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) core at 4.6 A resolution
分子名称: Acetyl-CoA carboxylase 1
著者Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T.
登録日2018-03-23
公開日2018-06-13
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
6G2I
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BU of 6g2i by Molmil
Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) at 5.9 A resolution
分子名称: Acetyl-CoA carboxylase 1, Breast cancer type 1 susceptibility protein
著者Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T.
登録日2018-03-23
公開日2018-06-13
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (5.9 Å)
主引用文献Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
6G2D
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BU of 6g2d by Molmil
Citrate-induced acetyl-CoA carboxylase (ACC-Cit) filament at 5.4 A resolution
分子名称: Acetyl-CoA carboxylase 1
著者Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T.
登録日2018-03-23
公開日2018-06-13
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
4KRD
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BU of 4krd by Molmil
Crystal Structure of Pho85-Pcl10 Complex
分子名称: Cyclin-dependent protein kinase PHO85, PHO85 cyclin-10
著者Quiocho, F.A, Zheng, F.
登録日2013-05-16
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献New Structural Insights into Phosphorylation-free Mechanism for Full Cyclin-dependent Kinase (CDK)-Cyclin Activity and Substrate Recognition.
J.Biol.Chem., 288, 2013
7LL3
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BU of 7ll3 by Molmil
S-adenosylmethionine synthetase co-crystallized with UppNHp
分子名称: (DIPHOSPHONO)AMINOPHOSPHONIC ACID, 1,2-ETHANEDIOL, 5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]uridine, ...
著者Tan, L.L, Jackson, C.J.
登録日2021-02-03
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases.
Jacs Au, 1, 2021
7LOW
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BU of 7low by Molmil
S-adenosylmethionine synthetase
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHATE ION, ...
著者Tan, L.L, Jackson, C.J.
登録日2021-02-10
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases.
Jacs Au, 1, 2021
7LOZ
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BU of 7loz by Molmil
S-adenosylmethionine synthetase
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHATE ION, ...
著者Tan, L.L, Jackson, C.J.
登録日2021-02-11
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases.
Jacs Au, 1, 2021
7LNN
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BU of 7lnn by Molmil
E. coli S-adenosyl methionine transferase co-crystallized with guanosine-5'-imidotriphosphate
分子名称: (DIPHOSPHONO)AMINOPHOSPHONIC ACID, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
著者Tan, L.L, Jackson, C.J.
登録日2021-02-08
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases.
Jacs Au, 1, 2021
7LO2
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BU of 7lo2 by Molmil
S-adenosylmethionine synthetase cocrystallized with CTP
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHATE ION, ...
著者Tan, L.L, Jackson, C.J.
登録日2021-02-09
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases.
Jacs Au, 1, 2021
3NSY
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BU of 3nsy by Molmil
The multi-copper oxidase CueO with six Met to Ser mutations (M358S,M361S,M362S,M364S,M366S,M368S)
分子名称: Blue copper oxidase cueO, COPPER (II) ION, CU-O-CU LINKAGE
著者Roberts, S.A, Montfort, W.R, Singh, S.K.
登録日2010-07-02
公開日2011-08-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of multicopper oxidase CueO bound to copper(I) and silver(I): functional role of a methionine-rich sequence.
J. Biol. Chem., 286, 2011
7LNH
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BU of 7lnh by Molmil
S-adenosylmethionine synthetase co-crystallized with UppNHp
分子名称: (2~{S})-2-azanyl-4-[[(2~{S},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl-methyl-$l^{3}-sulfanyl]butanoic acid, 1,2-ETHANEDIOL, S-adenosylmethionine synthase isoform type-2
著者Tan, L.L, Jackson, C.J.
登録日2021-02-07
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases.
Jacs Au, 1, 2021
5L3P
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BU of 5l3p by Molmil
Cryo-EM structure of stringent response factor RelA bound to ErmCL-stalled ribosome complex
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Arenz, S, Wilson, D.N.
登録日2016-05-24
公開日2016-07-20
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis.
Nucleic Acids Res., 44, 2016
7Y04
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BU of 7y04 by Molmil
Hsp90-AhR-p23 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Aryl hydrocarbon receptor, BERYLLIUM TRIFLUORIDE ION, ...
著者Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F.
登録日2022-06-03
公開日2023-01-04
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the cytosolic AhR complex.
Structure, 31, 2023
2QMO
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BU of 2qmo by Molmil
Crystal structure of dethiobiotin synthetase (bioD) from Helicobacter pylori
分子名称: CHLORIDE ION, Dethiobiotin synthetase
著者Chruszcz, M, Xu, X, Cuff, M, Cymborowski, M, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2007-07-16
公開日2007-07-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members.
Febs J., 279, 2012
7Z38
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BU of 7z38 by Molmil
Structure of the RAF1-HSP90-CDC37 complex (RHC-I)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
著者Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G.
登録日2022-03-01
公開日2022-09-14
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation.
Mol.Cell, 82, 2022
7Z37
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BU of 7z37 by Molmil
Structure of the RAF1-HSP90-CDC37 complex (RHC-II)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
著者Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G.
登録日2022-03-01
公開日2022-09-14
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation.
Mol.Cell, 82, 2022
6SW6
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BU of 6sw6 by Molmil
Crystal structure R264H mutant of the human S-adenosylmethionine synthetase 1
分子名称: S-adenosylmethionine synthase isoform type-1
著者Panmanee, J, Antonyuk, S.V, Hasnain, S.S.
登録日2019-09-19
公開日2020-06-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural basis of the dominant inheritance of hypermethioninemia associated with the Arg264His mutation in the MAT1A gene.
Acta Crystallogr D Struct Biol, 76, 2020
6SW5
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BU of 6sw5 by Molmil
Crystal structure of the human S-adenosylmethionine synthetase 1 (ligand-free form)
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, S-adenosylmethionine synthase isoform type-1
著者Panmanee, J, Antoyuk, S.V, Hasnain, S.S.
登録日2019-09-19
公開日2020-06-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis of the dominant inheritance of hypermethioninemia associated with the Arg264His mutation in the MAT1A gene.
Acta Crystallogr D Struct Biol, 76, 2020
8J07
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BU of 8j07 by Molmil
96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
分子名称: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ...
著者Gui, M, Brown, A.
登録日2023-04-09
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023

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