3DLA
X-ray crystal structure of glutamine-dependent NAD+ synthetase from Mycobacterium tuberculosis bound to NaAD+ and DON
Summary for 3DLA
Entry DOI | 10.2210/pdb3dla/pdb |
Descriptor | Glutamine-dependent NAD(+) synthetase, NICOTINIC ACID ADENINE DINUCLEOTIDE, 5-OXO-L-NORLEUCINE, ... (5 entities in total) |
Functional Keywords | glutaminase, nad+ synthetase, ammonia tunneling, enzyme, glutamine-dependent nad+ synthetase, glutamine-amido transferase, atp-binding, ligase, nad, nucleotide-binding |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 4 |
Total formula weight | 304045.36 |
Authors | LaRonde-LeBlanc, N.A.,Resto, M.,Gerratana, B. (deposition date: 2008-06-26, release date: 2009-03-10, Last modification date: 2019-10-23) |
Primary citation | LaRonde-LeBlanc, N.,Resto, M.,Gerratana, B. Regulation of active site coupling in glutamine-dependent NAD(+) synthetase. Nat.Struct.Mol.Biol., 16:421-429, 2009 Cited by PubMed: 19270703DOI: 10.1038/nsmb.1567 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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