3DLA
X-ray crystal structure of glutamine-dependent NAD+ synthetase from Mycobacterium tuberculosis bound to NaAD+ and DON
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamine-dependent NAD(+) synthetase | polymer | 680 | 74855.4 | 4 | UniProt (P0A5L6) Pfam (PF00795) Pfam (PF02540) UniProt (by SIFTS) (P9WJJ3) | Mycobacterium tuberculosis | NAD(+) synthase [glutamine-hydrolyzing] |
| 2 | E, L, Q, V (A, B, C, D) | NICOTINIC ACID ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 4 | Chemie (DND) | |||
| 3 | F, G, H, I (A) | 5-OXO-L-NORLEUCINE | non-polymer | 145.2 | 4 | Chemie (ONL) | |||
| 4 | AA, J, K, M, N... (D, A, B, C) | GLYCEROL | non-polymer | 92.1 | 15 | Chemie (GOL) | |||
| 5 | BA, CA, DA, EA (A, B, C, D) | water | water | 18.0 | 1443 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 679 (UniProt: P0A5L6)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 299421.7 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 4623.7 | |
| All* | Total formula weight | 304045.4 |
