PDB: 5515 件ウェブページステータス検索Chemie searchBIRD

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5EZ9	A de novo designed heptameric coiled coil CC-Hept-I-H-I 分子名称: CC-Hept-L22H, HEXANE-1,6-DIOL 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-11-26 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5F2Y	A de novo designed heptameric coiled coil CC-Hept-homoCys-H-E 分子名称: CC-Hept-hCys-H-E 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-12-02 公開日 2016-07-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZA	A de novo designed heptameric coiled coil CC-Hept-I18C-L22H 分子名称: CC-Hept-C-H-I, GLYCEROL 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-11-26 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZC	A de novo designed heptameric coiled coil CC-Hept-I18C-L22H-I25E 分子名称: CC-Hept-C-H-E 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-11-26 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EON	Crystal structure of a de novo antiparallel coiled-coil hexamer - ACC-Hex 分子名称: ACC-Hex 著者 Spencer, R.K, Hochbaum, A.I. 登録日 2015-11-10 公開日 2016-05-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.696 Å) 主引用文献 X-ray Crystallographic Structure and Solution Behavior of an Antiparallel Coiled-Coil Hexamer Formed by de Novo Peptides. Biochemistry, 55, 2016
1L4X	Octameric de novo designed peptide 分子名称: CHLORIDE ION, MAGNESIUM ION, SIN-ASP-GLU-LEU-GLU-ARG-ALA-ILE-ARG-GLU-LEU-ALA-ALA-ARG-ILE-LYS-NH2 著者 Meier, M, Lustig, A, Aebi, U, Burkhard, P. 登録日 2002-03-06 公開日 2002-11-13 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Removing an interhelical salt bridge abolishes coiled-coil formation in a de novo designed peptide J.STRUCT.BIOL., 137, 2002
5EHB	A de novo designed hexameric coiled-coil peptide with iodotyrosine 分子名称: pHiosYI 著者 Lizatovic, R, Aurelius, O, Stenstrom, O, Drakenberg, T, Akke, M, Logan, D.T, Andre, I. 登録日 2015-10-28 公開日 2016-06-15 最終更新日 2018-01-17 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 A De Novo Designed Coiled-Coil Peptide with a Reversible pH-Induced Oligomerization Switch. Structure, 24, 2016
7OSU	sTIM11noCys-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 1) 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Romero-Romero, S, Kordes, S, Hocker, B. 登録日 2021-06-09 公開日 2021-12-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7OT7	sTIM11noCys-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 2) 分子名称: sTIM11noCys-SB 著者 Romero-Romero, S, Kordes, S, Hocker, B. 登録日 2021-06-09 公開日 2021-12-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
4KYZ	Three-dimensional structure of triclinic form of de novo design insertion domain, Northeast Structural Genomics Consortium (NESG) Target OR327 分子名称: Designed protein OR327 著者 Kuzin, A, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Lee, D, Gleixner, J, Baker, D, Everett, J.K, Acton, T.B, Kornhaber, G, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2013-05-29 公開日 2013-07-24 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.492 Å) 主引用文献 Precise assembly of complex beta sheet topologies from de novo designed building blocks. Elife, 4, 2015
1IVL	THE DE NOVO DESIGN OF AN ANTIBODY COMBINING SITE: CRYSTALLOGRAPHIC ANALYSIS OF THE VL DOMAIN CONFIRMS THE STRUCTURAL MODEL 分子名称: IGG-KAPPA M29B FV (LIGHT CHAIN), ISOPROPYL ALCOHOL 著者 Essen, L.-O, Skerra, A. 登録日 1994-05-04 公開日 1994-08-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 The de novo design of an antibody combining site. Crystallographic analysis of the VL domain confirms the structural model. J.Mol.Biol., 238, 1994
5TX8	Solution structure of the de novo mini protein gHH_44 分子名称: HH2 著者 Buchko, G.W, Bahl, C.D, Baker, D. 登録日 2016-11-15 公開日 2017-09-27 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides. Protein Sci., 27, 2018
1C3C	T. MARITIMA ADENYLOSUCCINATE LYASE 分子名称: PROTEIN (ADENYLOSUCCINATE LYASE) 著者 Toth, E.A, Yeates, T.O. 登録日 1999-07-27 公開日 2000-02-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway. Structure Fold.Des., 8, 2000
1C3U	T. MARITIMA ADENYLOSUCCINATE LYASE 分子名称: ADENYLOSUCCINATE LYASE, SULFATE ION 著者 Toth, E.A, Yeates, T.O. 登録日 1999-07-28 公開日 2000-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway. Structure Fold.Des., 8, 2000
4DZN	A de novo designed Coiled Coil CC-pIL 分子名称: COILED-COIL PEPTIDE CC-PIL 著者 Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. 登録日 2012-03-01 公開日 2012-08-29 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
4DZM	A de novo designed Coiled Coil CC-Di 分子名称: COILED-COIL PEPTIDE CC-DI 著者 Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. 登録日 2012-03-01 公開日 2012-08-29 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
8CCR	Crystal structure of the T19D mutant of the de novo diheme binding 4D2 分子名称: (2S)-2-hydroxybutanedioic acid, 4D2 (mutant T19D), CHLORIDE ION, ... 著者 Barringer, R, Anderson, R. 登録日 2023-01-27 公開日 2023-08-09 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An expandable, modular de novo protein platform for precision redox engineering. Proc.Natl.Acad.Sci.USA, 120, 2023
3B83	Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design. 分子名称: TEN-D3 著者 Hu, X, Ke, H, Kuhlman, B. 登録日 2007-10-31 公開日 2008-11-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design. Structure, 16, 2008
7BIM	A de novo designed nonameric coiled coil, CC-Type2-(GgLaId)4 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Nonameric de novo coiled coil CC-Type2-(GgLaId)4 著者 Shelley, K.L, Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2021-01-12 公開日 2021-04-21 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
7BEY	Het-N2-SO3- - De novo designed three-helix heterodimer with Cysteine S-sulfate at the N2 position of the alpha-helix 分子名称: 'Cys-N2-SO3-' Strand, 'Positive' Strand, SULFATE ION 著者 McEwen, A.G, Poussin-Courmontagne, P, Naudin, E.A, DeGrado, W.F, Torbeev, V. 登録日 2021-01-06 公開日 2021-03-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Acyl Transfer Catalytic Activity in De Novo Designed Protein with N-Terminus of alpha-Helix As Oxyanion-Binding Site. J.Am.Chem.Soc., 143, 2021
6LLQ	Solution NMR structure of de novo Rossmann2x2 fold with most of the core mutated to valine, R2x2_VAL88 分子名称: VAL88 著者 Kobayashi, N, Sugiki, T, Fujiwara, T, Koga, R, Yamamoto, M, Kosugi, T, Koga, N. 登録日 2019-12-23 公開日 2020-12-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Robust folding of a de novo designed ideal protein even with most of the core mutated to valine. Proc.Natl.Acad.Sci.USA, 117, 2020
5JI4	Solution structure of the de novo mini protein gEEHE_02 分子名称: W37 著者 Buchko, G.W, Bahl, C.D, Pulavarti, S.V, Baker, D, Szyperski, T. 登録日 2016-04-21 公開日 2016-09-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
5JHI	Solution structure of the de novo mini protein gEHE_06 分子名称: W35 著者 Buchko, G.W, Bahl, C.D, Gilmore, J.M, Pulavarti, S.V, Baker, D, Szyperski, T. 登録日 2016-04-21 公開日 2016-09-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
7NFJ	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L28Y. 分子名称: CC-Type2-(LaId)4-L28Y 著者 Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2021-02-07 公開日 2022-03-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFL	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24N. 分子名称: CC-Type2-(LaId)4-I24N 著者 Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2021-02-07 公開日 2022-03-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023

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