PDB: 166 件ウェブページステータス検索Chemie searchBIRD

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6SGR	Cryo-EM structure of Escherichia coli AcrBZ and DARPin in Saposin A-nanodisc with cardiolipin 分子名称: DARPin, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrB 著者 Szewczak-Harris, A, Du, D, Newman, C, Neuberger, A, Luisi, B.F. 登録日 2019-08-05 公開日 2020-05-13 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment. Structure, 28, 2020
4C48	Crystal structure of AcrB-AcrZ complex 分子名称: ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-BETA-D-MALTOSIDE, ... 著者 Du, D, James, N, Klimont, E, Luisi, B.F. 登録日 2013-09-02 公開日 2014-04-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of the AcrAB-TolC multidrug efflux pump. Nature, 509, 2014
3T53	Crystal structures of the extrusion state of the CusBA adaptor-transporter complex 分子名称: COPPER (II) ION, Cation efflux system protein CusA, Cation efflux system protein CusB 著者 Su, C.-C, Long, F, Yu, E.W. 登録日 2011-07-26 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.37 Å) 主引用文献 Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System. J.Mol.Biol., 422, 2012
3T51	Crystal structures of the pre-extrusion and extrusion states of the CusBA adaptor-transporter complex 分子名称: COPPER (II) ION, Cation efflux system protein CusA, Cation efflux system protein CusB 著者 Su, C.-C, Long, F, Yu, E.W. 登録日 2011-07-26 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System. J.Mol.Biol., 422, 2012
5V5S	multi-drug efflux; membrane transport; RND superfamily; Drug resistance 分子名称: Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB, Outer membrane protein TolC 著者 wang, Z, fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D. 登録日 2017-03-15 公開日 2017-04-19 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump. Elife, 6, 2017
5NG5	multi-drug efflux; membrane transport; RND superfamily; Drug resistance 分子名称: 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, ... 著者 Wang, Z, Fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D. 登録日 2017-03-16 公開日 2017-04-19 最終更新日 2017-08-02 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump. Elife, 6, 2017
6IOK	Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state) 分子名称: Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM 著者 Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E. 登録日 2018-10-30 公開日 2019-04-03 最終更新日 2019-04-17 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism. Nat Commun, 10, 2019
3NE5	Crystal structure of the CusBA heavy-metal efflux complex from Escherichia coli 分子名称: Cation efflux system protein cusA, Cation efflux system protein cusB 著者 Su, C.-C. 登録日 2010-06-08 公開日 2011-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.898 Å) 主引用文献 Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli. Nature, 470, 2011
5O66	Asymmetric AcrABZ-TolC 分子名称: Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB, ... 著者 Du, D, Luisi, B.F. 登録日 2017-06-05 公開日 2017-06-14 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump. Elife, 6, 2017
6IOL	Cryo-EM structure of multidrug efflux pump MexAB-OprM (60 degree state) 分子名称: Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM 著者 Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E. 登録日 2018-10-30 公開日 2019-04-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.76 Å) 主引用文献 Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism. Nat Commun, 10, 2019
3T56	Crystal structure of the pre-extrusion state of the CusBA adaptor-transporter complex 分子名称: COPPER (II) ION, Cation efflux system protein CusA, Cation efflux system protein CusB 著者 Su, C.-C, Long, F, Yu, E.W. 登録日 2011-07-26 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System. J.Mol.Biol., 422, 2012
6TA5	OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs 分子名称: Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM 著者 Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. 登録日 2019-10-29 公開日 2020-09-16 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
6TA6	MexAB assembly of the Pseudomonas MexAB-OprM efflux pump reconstituted in nanodiscs 分子名称: Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM 著者 Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. 登録日 2019-10-29 公開日 2020-09-16 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
4DNT	Crystal structure of the CusBA heavy-metal efflux complex from Escherichia coli, mutant 分子名称: Cation efflux system protein CusA, Cation efflux system protein CusB 著者 Su, C.-C, Long, F, Yu, E. 登録日 2012-02-09 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System. J.Mol.Biol., 422, 2012
4DOP	Crystal structure of the CusBA heavy-metal efflux complex from Escherichia coli, R mutant 分子名称: Cation efflux system protein CusA, Cation efflux system protein CusB 著者 Su, C.-C, Long, F, Yu, E. 登録日 2012-02-10 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Charged Amino Acids (R83, E567, D617, E625, R669, and K678) of CusA Are Required for Metal Ion Transport in the Cus Efflux System. J.Mol.Biol., 422, 2012
4DNR	Crystal structure of the CusBA heavy-metal efflux complex from Escherichia coli, E716F mutant 分子名称: COPPER (II) ION, Cation efflux system protein CusA, Cation efflux system protein CusB 著者 Su, C.-C, Long, F, Yu, E. 登録日 2012-02-08 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.68 Å) 主引用文献 Crystal structures of the pre-extrusion and extrusion states of the CusBA adaptor-transporter complex To be Published

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