6IOK
Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state)
Summary for 6IOK
| Entry DOI | 10.2210/pdb6iok/pdb |
| EMDB information | 9695 |
| Descriptor | Multidrug resistance protein MexA, Outer membrane protein OprM, Multidrug resistance protein MexB (3 entities in total) |
| Functional Keywords | multidrug resistance, efflux, complex, membrane protein |
| Biological source | Pseudomonas aeruginosa PAO1 More |
| Total number of polymer chains | 12 |
| Total formula weight | 729795.80 |
| Authors | Tsutsumi, K.,Yonehara, R.,Nakagawa, A.,Yamashita, E. (deposition date: 2018-10-30, release date: 2019-04-03, Last modification date: 2019-04-17) |
| Primary citation | Tsutsumi, K.,Yonehara, R.,Ishizaka-Ikeda, E.,Miyazaki, N.,Maeda, S.,Iwasaki, K.,Nakagawa, A.,Yamashita, E. Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism. Nat Commun, 10:1520-1520, 2019 Cited by PubMed: 30944318DOI: 10.1038/s41467-019-09463-9 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.64 Å) |
Structure validation
Download full validation report
