1DVN
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3EOX
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3EVJ
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![BU of 3evj by Molmil](/molmil-images/mine/3evj) | Intermediate structure of antithrombin bound to the natural pentasaccharide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, ... | 著者 | Huntington, J.A, Belzar, K.J. | 登録日 | 2008-10-13 | 公開日 | 2008-10-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The critical role of hinge-region expulsion in the induced-fit heparin binding mechanism of antithrombin. J. Mol. Biol., 386, 2009
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1F0C
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![BU of 1f0c by Molmil](/molmil-images/mine/1f0c) | STRUCTURE OF THE VIRAL SERPIN CRMA | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ICE INHIBITOR | 著者 | Renatus, M, Zhou, Q, Stennicke, H.R, Snipas, S.J, Turk, D, Bankston, L.A, Liddington, R.C, Salvesen, G.S. | 登録日 | 2000-05-15 | 公開日 | 2000-09-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Crystal structure of the apoptotic suppressor CrmA in its cleaved form. Structure Fold.Des., 8, 2000
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1E04
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![BU of 1e04 by Molmil](/molmil-images/mine/1e04) | PLASMA BETA ANTITHROMBIN-III | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, GLYCEROL, ... | 著者 | Mccoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W. | 登録日 | 2000-03-09 | 公開日 | 2000-06-02 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity. J.Mol.Biol., 326, 2003
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1DVM
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![BU of 1dvm by Molmil](/molmil-images/mine/1dvm) | ACTIVE FORM OF HUMAN PAI-1 | 分子名称: | CHLORIDE ION, PLASMINOGEN ACTIVATOR INHIBITOR-1 | 著者 | Stout, T.J, Graham, H, Buckley, D.I, Matthews, D.J. | 登録日 | 2000-01-21 | 公開日 | 2000-09-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of active and latent PAI-1: a possible stabilizing role for chloride ions. Biochemistry, 39, 2000
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3F02
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1E03
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![BU of 1e03 by Molmil](/molmil-images/mine/1e03) | PLASMA ALPHA ANTITHROMBIN-III AND PENTASACCHARIDE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ... | 著者 | McCoy, A.J, Jin, L, Abrahams, J.-P, Skinner, R, Carrell, R.W. | 登録日 | 2000-03-09 | 公開日 | 2000-06-02 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity. J.Mol.Biol., 326, 2003
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1DZH
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![BU of 1dzh by Molmil](/molmil-images/mine/1dzh) | P14-FLUORESCEIN-N135Q-S380C-ANTITHROMBIN-III | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... | 著者 | Mccoy, A.J, Huntington, J.A, Carrell, R.W. | 登録日 | 2000-02-28 | 公開日 | 2000-05-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions. J.Biol.Chem., 275, 2000
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1E05
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![BU of 1e05 by Molmil](/molmil-images/mine/1e05) | PLASMA ALPHA ANTITHROMBIN-III | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... | 著者 | McCoy, A.J, Skinner, R, Abrahams, J.-P, Pei, X.Y, Carrell, R.W. | 登録日 | 2000-03-09 | 公開日 | 2000-06-02 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structure of Beta-Antithrombin and the Effect of Glycosylation on Antithrombin'S Heparin Affinity and Activity. J.Mol.Biol., 326, 2003
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1DZG
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![BU of 1dzg by Molmil](/molmil-images/mine/1dzg) | N135Q-S380C-ANTITHROMBIN-III | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... | 著者 | McCoy, A.J, Huntington, J.A, Carrell, R.W. | 登録日 | 2000-02-28 | 公開日 | 2000-05-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions. J.Biol.Chem., 275, 2000
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3DRM
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![BU of 3drm by Molmil](/molmil-images/mine/3drm) | 2.2 Angstrom Crystal Structure of Thr114Phe Alpha1-Antitrypsin | 分子名称: | Alpha-1-antitrypsin | 著者 | Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E. | 登録日 | 2008-07-11 | 公開日 | 2009-03-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J.Mol.Biol., 387, 2009
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3CWL
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![BU of 3cwl by Molmil](/molmil-images/mine/3cwl) | Crystal structure of alpha-1-antitrypsin, crystal form B | 分子名称: | Alpha-1-antitrypsin, CHLORIDE ION | 著者 | Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W. | 登録日 | 2008-04-22 | 公開日 | 2008-09-23 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding. Protein Sci., 17, 2008
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3DY0
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![BU of 3dy0 by Molmil](/molmil-images/mine/3dy0) | Crystal Structure of Cleaved PCI Bound to Heparin | 分子名称: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-terminus Plasma serine protease inhibitor, GLYCEROL, ... | 著者 | Li, W, Huntington, J.A. | 登録日 | 2008-07-25 | 公開日 | 2008-10-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The heparin binding site of protein C inhibitor is protease-dependent. J.Biol.Chem., 283, 2008
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3DRU
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![BU of 3dru by Molmil](/molmil-images/mine/3dru) | Crystal Structure of Gly117Phe Alpha1-Antitrypsin | 分子名称: | Alpha-1-antitrypsin | 著者 | Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E. | 登録日 | 2008-07-11 | 公開日 | 2009-03-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J.Mol.Biol., 387, 2009
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3DLW
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![BU of 3dlw by Molmil](/molmil-images/mine/3dlw) | Antichymotrypsin | 分子名称: | Alpha-1-antichymotrypsin | 著者 | Feil, S.C. | 登録日 | 2008-06-29 | 公開日 | 2009-07-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Identification and characterization of a misfolded monomeric serpin formed at physiological temperature J.Mol.Biol., 403, 2010
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3F5N
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1DB2
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![BU of 1db2 by Molmil](/molmil-images/mine/1db2) | CRYSTAL STRUCTURE OF NATIVE PLASMINOGEN ACTIVATOR INHIBITOR-1 | 分子名称: | PLASMINOGEN ACTIVATOR INHIBITOR-1 | 著者 | Nar, H, Bauer, M, Stassen, J.M, Lang, D, Gils, A, Declerck, P. | 登録日 | 1999-11-02 | 公開日 | 1999-11-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation. J.Mol.Biol., 297, 2000
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3FGQ
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![BU of 3fgq by Molmil](/molmil-images/mine/3fgq) | Crystal structure of native human neuroserpin | 分子名称: | GLYCEROL, Neuroserpin | 著者 | Takehara, S, Yang, X, Mikami, B, Onda, M. | 登録日 | 2008-12-08 | 公開日 | 2009-04-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability J.Mol.Biol., 388, 2009
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3CWM
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![BU of 3cwm by Molmil](/molmil-images/mine/3cwm) | Crystal structure of alpha-1-antitrypsin complexed with citrate | 分子名称: | Alpha-1-antitrypsin, CITRIC ACID | 著者 | Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W. | 登録日 | 2008-04-22 | 公開日 | 2008-09-23 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding. Protein Sci., 17, 2008
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1HP7
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![BU of 1hp7 by Molmil](/molmil-images/mine/1hp7) | A 2.1 ANGSTROM STRUCTURE OF AN UNCLEAVED ALPHA-1-ANTITRYPSIN SHOWS VARIABILITY OF THE REACTIVE CENTER AND OTHER LOOPS | 分子名称: | ALPHA-1-ANTITRYPSIN, BETA-MERCAPTOETHANOL, ZINC ION | 著者 | Kim, S.-J, Woo, J.-R, Seo, E.J, Yu, M.-H, Ryu, S.-E. | 登録日 | 2000-12-12 | 公開日 | 2001-03-14 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A 2.1 A resolution structure of an uncleaved alpha(1)-antitrypsin shows variability of the reactive center and other loops. J.Mol.Biol., 306, 2001
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1HLE
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![BU of 1hle by Molmil](/molmil-images/mine/1hle) | CRYSTAL STRUCTURE OF CLEAVED EQUINE LEUCOCYTE ELASTASE INHIBITOR DETERMINED AT 1.95 ANGSTROMS RESOLUTION | 分子名称: | CALCIUM ION, HORSE LEUKOCYTE ELASTASE INHIBITOR | 著者 | Baumann, U, Bode, W, Huber, R, Travis, J, Potempa, J. | 登録日 | 1992-04-13 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution. J.Mol.Biol., 226, 1992
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1IMV
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![BU of 1imv by Molmil](/molmil-images/mine/1imv) | 2.85 A crystal structure of PEDF | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PIGMENT EPITHELIUM-DERIVED FACTOR | 著者 | Simonovic, M, Gettins, P.G.W, Volz, K. | 登録日 | 2001-05-11 | 公開日 | 2001-09-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor. Proc.Natl.Acad.Sci.USA, 98, 2001
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1AS4
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![BU of 1as4 by Molmil](/molmil-images/mine/1as4) | CLEAVED ANTICHYMOTRYPSIN A349R | 分子名称: | ACETATE ION, ANTICHYMOTRYPSIN | 著者 | Lukacs, C.M, Christianson, D.W. | 登録日 | 1997-08-12 | 公開日 | 1998-02-25 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
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1IZ2
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![BU of 1iz2 by Molmil](/molmil-images/mine/1iz2) | Interactions causing the kinetic trap in serpin protein folding | 分子名称: | alpha-D-glucopyranose-(1-2)-(5R)-5-[(2R)-2-hydroxynonyl]-beta-D-xylulofuranose, alpha1-antitrypsin | 著者 | Im, H, Woo, M.-S, Hwang, K.Y, Yu, M.-H. | 登録日 | 2002-09-19 | 公開日 | 2003-02-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Interactions causing the kinetic trap in serpin protein folding J.BIOL.CHEM., 277, 2002
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