1HP7

A 2.1 ANGSTROM STRUCTURE OF AN UNCLEAVED ALPHA-1-ANTITRYPSIN SHOWS VARIABILITY OF THE REACTIVE CENTER AND OTHER LOOPS

Summary for 1HP7

DescriptorALPHA-1-ANTITRYPSIN, ZINC ION, BETA-MERCAPTOETHANOL, ... (4 entities in total)
Functional Keywordsuncleaved alpha-1-antitrypsin serpin, protein binding
Biological sourceHomo sapiens (human)
Cellular locationSecreted. Short peptide from AAT: Secreted, extracellular space, extracellular matrix P01009
Total number of polymer chains1
Total molecular weight44736.44
Authors
Kim, S.-J.,Woo, J.-R.,Seo, E.J.,Yu, M.-H.,Ryu, S.-E. (deposition date: 2000-12-12, release date: 2001-03-14, Last modification date: 2017-10-04)
Primary citation
Kim, S.,Woo, J.,Seo, E.J.,Yu, M.,Ryu, S.
A 2.1 A resolution structure of an uncleaved alpha(1)-antitrypsin shows variability of the reactive center and other loops.
J.Mol.Biol., 306:109-119, 2001
PubMed: 11178897 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.2000.4357
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.272152.1%3.0%3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution