7EOR
| Structure of the human GluN1/GluN2A NMDA receptor in the glycine/glutamate/GNE-6901 bound state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-[(4-fluoranylphenoxy)methyl]-3-[(1~{R},2~{R})-2-(hydroxymethyl)cyclopropyl]-2-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one, Glutamate receptor ionotropic, ... | 著者 | Wang, H, Zhu, S. | 登録日 | 2021-04-22 | 公開日 | 2021-06-30 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Gating mechanism and a modulatory niche of human GluN1-GluN2A NMDA receptors. Neuron, 109, 2021
|
|
7LZH
| Structure of the glutamate receptor-like channel AtGLR3.4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | 著者 | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | 登録日 | 2021-03-09 | 公開日 | 2021-07-28 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
|
|
7LZI
| |
7LZ2
| Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with methionine | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | 登録日 | 2021-03-08 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
|
|
7LZ0
| Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with glutamate | 分子名称: | CHLORIDE ION, GLUTAMIC ACID, GLYCEROL, ... | 著者 | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | 登録日 | 2021-03-08 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
|
|
7LZ1
| Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with serine | 分子名称: | GLYCEROL, Glutamate receptor 3.4, SERINE, ... | 著者 | Gangwar, S.P, Green, M.N, Sobolevsky, A.I. | 登録日 | 2021-03-08 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4. Mol.Cell, 81, 2021
|
|
7LVT
| |
7LEP
| The composite LBD-TMD structure combined from all hippocampal AMPAR subtypes at 3.25 Angstrom resolution | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol, DECANE, ... | 著者 | Yu, J, Rao, P, Gouaux, E. | 登録日 | 2021-01-14 | 公開日 | 2021-05-12 | 最終更新日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. Nature, 594, 2021
|
|
7LDE
| native AMPA receptor | 分子名称: | 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ... | 著者 | Yu, J, Rao, P, Gouaux, E. | 登録日 | 2021-01-13 | 公開日 | 2021-05-12 | 最終更新日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. Nature, 594, 2021
|
|
7LDD
| native AMPA receptor | 分子名称: | 11B8 scFv, 15F1 Fab heavy chain, 15F1 Fab light chain, ... | 著者 | Yu, J, Rao, P, Gouaux, E. | 登録日 | 2021-01-13 | 公開日 | 2021-05-12 | 最終更新日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. Nature, 594, 2021
|
|
7KS0
| GluK2/K5 with 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX) | 分子名称: | Glutamate receptor ionotropic, kainate 2, kainate 5,Green fluorescent protein chimera | 著者 | Khanra, N, Brown, P.M.G.E, Perozzo, A.M, Bowie, D, Meyerson, J.R. | 登録日 | 2020-11-20 | 公開日 | 2021-03-24 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | 主引用文献 | Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor. Elife, 10, 2021
|
|
7KS3
| GluK2/K5 with L-Glu | 分子名称: | Glutamate receptor ionotropic, kainate 2, kainate 5,Green fluorescent protein chimera | 著者 | Khanra, N, Brown, P.M.G.E, Perozzo, A.M, Bowie, D, Meyerson, J.R. | 登録日 | 2020-11-20 | 公開日 | 2021-03-24 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor. Elife, 10, 2021
|
|
6ZYU
| Structure of the GluA2 ligand-binding domain (L483Y-N754S) in complex with glutamate and BPAM549 | 分子名称: | (4~{R})-4-cyclopropyl-7-fluoranyl-3,4-dihydro-2~{H}-thiochromene 1,1-dioxide, (4~{S})-4-cyclopropyl-7-fluoranyl-3,4-dihydro-2~{H}-thiochromene 1,1-dioxide, ACETATE ION, ... | 著者 | Dorosz, J, Christensen, K.M, Kastrup, J.S. | 登録日 | 2020-08-03 | 公開日 | 2021-08-11 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Development of Thiochroman Dioxide Analogues of Benzothiadiazine Dioxides as New Positive Allosteric Modulators of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors. Acs Chem Neurosci, 12, 2021
|
|
6XSR
| |
6WHS
| GluN1b-GluN2B NMDA receptor in non-active 1 conformation at 3.95 angstrom resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WHV
| GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 2 | 分子名称: | (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WI1
| GluN1b-GluN2B NMDA receptor in active conformation stabilized by inter-GluN1b-GluN2B subunit cross-linking | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WHR
| GluN1b-GluN2B NMDA receptor in non-active 2 conformation at 4 angstrom resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WHT
| GluN1b-GluN2B NMDA receptor in active conformation at 4.4 angstrom resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4.39 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WI0
| GluN1b-GluN2B NMDA receptor in complex with GluN1 antagonist L689,560, class 2 | 分子名称: | (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WHX
| GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 2 | 分子名称: | (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WHW
| GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 1 | 分子名称: | (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ionotropic glutamate receptor , ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WHU
| GluN1b-GluN2B NMDA receptor in complex with SDZ 220-040 and L689,560, class 1 | 分子名称: | (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, (2S)-2-amino-3-[2',4'-dichloro-4-hydroxy-5-(phosphonomethyl)biphenyl-3-yl]propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6WHY
| GluN1b-GluN2B NMDA receptor in complex with GluN1 antagonist L689,560, class 1 | 分子名称: | (2R,4S)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T, Tajima, N, Furukawa, H. | 登録日 | 2020-04-08 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | 主引用文献 | Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell, 182, 2020
|
|
6YK4
| Structure of the AMPA receptor GluA2o ligand-binding domain (S1S2J) in complex with the compound ( S) - 1- [2'-Amino-2'-carboxyethyl]-6-methyl-5 ,7- dihydropyrrolo[3,4-d]pyrimidin-2,4(1H,3H)-dione at resolution 1.00A | 分子名称: | (2~{S})-2-azanyl-3-[6-methyl-2,4-bis(oxidanylidene)-5,7-dihydropyrrolo[3,4-d]pyrimidin-1-yl]propanoic acid, CHLORIDE ION, GLYCEROL, ... | 著者 | Frydenvang, K, Kastrup, J.S. | 登録日 | 2020-04-05 | 公開日 | 2020-06-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (0.999 Å) | 主引用文献 | Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding Interactions. Acs Chem Neurosci, 11, 2020
|
|