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4UUS
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BU of 4uus by Molmil
CRYSTAL STRUCTURE OF A UBX-EXD-DNA COMPLEX INCLUDING THE UBDA MOTIF
分子名称: 5'-D(*AP*CP*GP*TP*GP*AP*TP*TP*TP*AP*TP*GP*GP*CP*G)-3', 5'-D(*GP*TP*CP*GP*CP*CP*AP*TP*AP*AP*AP*TP*CP*AP*C)-3', HOMEOTIC PROTEIN EXTRADENTICLE, ...
著者Foos, N, Mate, M.J, Ortiz-Lombardia, M.
登録日2014-07-31
公開日2015-02-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献A Flexible Extension of the Drosophila Ultrabithorax Homeodomain Defines a Novel Hox/Pbc Interaction Mode.
Structure, 23, 2015
7U0I
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BU of 7u0i by Molmil
Structure of LIN28b nucleosome bound 2 OCT4
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Tengfei, L, Guan, R, Bai, Y.
登録日2022-02-18
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
7U0G
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BU of 7u0g by Molmil
structure of LIN28b nucleosome bound 3 OCT4
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2022-02-18
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
3D1N
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BU of 3d1n by Molmil
Structure of human Brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter
分子名称: 5'-D(*DAP*DGP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DA)-3', 5'-D(*DTP*DTP*DAP*DTP*DTP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DCP*DT)-3', POU domain, ...
著者Pereira, J.H, Ha, S.C, Kim, S.-H.
登録日2008-05-06
公開日2009-05-26
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of human Brn-5 transcription factor in complex with CRH gene promoter.
J.Struct.Biol., 167, 2009
1S7E
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BU of 1s7e by Molmil
Solution structure of HNF-6
分子名称: Hepatocyte nuclear factor 6
著者Liao, X, Sheng, W.
登録日2004-01-29
公開日2004-12-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the hepatocyte nuclear factor 6alpha and its interaction with DNA.
J.Biol.Chem., 279, 2004
5NO6
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BU of 5no6 by Molmil
TEAD4-HOXB13 complex bound to DNA
分子名称: DNA, Homeobox protein Hox-B13, Transcriptional enhancer factor TEF-3
著者Morgunova, E, Jolma, A, Yin, Y, Popov, A, Taipale, J.
登録日2017-04-11
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献TEAD4-HOXB13 complex bound to DNA
To Be Published
6WC5
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BU of 6wc5 by Molmil
Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex
分子名称: Homeobox protein Nkx-2.5, Myocardin enhancer DNA, Myocyte-specific enhancer factor 2B
著者Chen, L, Lei, X.
登録日2020-03-29
公開日2020-07-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface.
J.Mol.Biol., 432, 2020
6WC2
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BU of 6wc2 by Molmil
Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex
分子名称: Homeobox protein Nkx-2.5, MEF2 Chimera,Myocyte-specific enhancer factor 2B,Myocyte-specific enhancer factor 2A, Myocardin Enhancer DNA
著者Lei, X, Chen, L.
登録日2020-03-29
公開日2020-07-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface.
J.Mol.Biol., 432, 2020
8SPS
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BU of 8sps by Molmil
High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b
分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2023-05-03
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
8SPU
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BU of 8spu by Molmil
Structure of ESRRB nucleosome bound OCT4 at site c
分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2023-05-03
公開日2023-06-28
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
2XSD
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BU of 2xsd by Molmil
Crystal Structure of the dimeric Oct-6 (Pou3f1) POU domain bound to palindromic MORE DNA
分子名称: 1,2-ETHANEDIOL, 5'-D(*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*AP)-3', 5'-D(*CP*CP*TP*CP*AP*TP*GP*CP*AP*TP*AP)-3', ...
著者Jauch, R, Choo, S.H, Ng, C.K.L, Kolatkar, P.R.
登録日2010-09-28
公開日2010-10-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.049 Å)
主引用文献Crystal Structure of the Dimeric Oct6 (POU3F1) POU Domain Bound to Palindromic More DNA.
Proteins, 79, 2011
5EGO
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BU of 5ego by Molmil
HOXB13-MEIS1 heterodimer bound to methylated DNA
分子名称: DNA (5'-D(*CP*CP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*GP*G)-3'), Homeobox protein Hox-B13, ...
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-27
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Science, 356, 2017
5EG0
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BU of 5eg0 by Molmil
HOXB13-MEIS1 heterodimer bound to DNA
分子名称: DNA (5'-D(*CP*CP*TP*CP*GP*TP*AP*AP*AP*AP*CP*TP*GP*TP*CP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*TP*TP*TP*TP*AP*CP*GP*AP*GP*G)-3'), Homeobox protein Hox-B13, ...
著者Morgunova, E, Yin, Y, Jolma, A, Popov, A, Taipale, J.
登録日2015-10-26
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Molecular basis of recognition of two distinct DNA sequences by a single transcription factor
To Be Published
6T90
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BU of 6t90 by Molmil
OCT4-SOX2-bound nucleosome - SHL-6
分子名称: DNA (146-MER), Green fluorescent protein,POU domain, class 5, ...
著者Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H.
登録日2019-10-25
公開日2020-05-06
最終更新日2020-07-08
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
1HF0
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BU of 1hf0 by Molmil
Crystal structure of the DNA-binding domain of Oct-1 bound to DNA as a dimer
分子名称: DNA 5'-D(*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP* CP*AP*AP*AP*TP*GP*GP*AP*G)-3', DNA 5'-D(*CP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP* TP*CP*AP*AP*AP*TP*GP*TP*G)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1
著者Remenyi, A, Tomilin, A, Pohl, E, Scholer, H.R, Wilmanns, M.
登録日2000-11-27
公開日2001-11-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping
Mol.Cell, 8, 2001
1GT0
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BU of 1gt0 by Molmil
Crystal structure of a POU/HMG/DNA ternary complex
分子名称: 5'-D(*AP*TP*CP*CP*CP*AP*TP*TP*AP*GP* CP*AP*TP*CP*CP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3', 5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*TP*TP* GP*GP*AP* TP*GP*CP*TP*AP*AP*TP*GP*GP*GP*A)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1, ...
著者Remenyi, A, Wilmanns, M.
登録日2002-01-09
公開日2003-01-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of a POU/Hmg/DNA Ternary Complex Suggests Differential Assembly of Oct4 and Sox2 on Two Enhancers
Genes Dev., 17, 2003
8G8E
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BU of 8g8e by Molmil
Human Oct4 bound to nucleosome with human LIN28B sequence
分子名称: LIN28B DNA (32-MER), POU domain, class 5, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G87
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BU of 8g87 by Molmil
Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region)
分子名称: POU domain, class 5, transcription factor 1, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8B
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BU of 8g8b by Molmil
Nucleosome with human nMatn1 sequence in complex with Human Oct4
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G8G
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BU of 8g8g by Molmil
Interaction of H3 tail in LIN28B nucleosome with Oct4
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G88
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BU of 8g88 by Molmil
Human Oct4 bound to nucleosome with human nMatn1 sequence
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
1MH3
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BU of 1mh3 by Molmil
maltose binding-a1 homeodomain protein chimera, crystal form I
分子名称: maltose binding-a1 homeodomain protein chimera
著者Ke, A, Wolberger, C.
登録日2002-08-19
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera
Protein Sci., 12, 2003
1MH4
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maltose binding-a1 homeodomain protein chimera, crystal form II
分子名称: maltose binding-a1 homeodomain protein chimera
著者Ke, A, Wolberger, C.
登録日2002-08-19
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera
Protein Sci., 12, 2003
1MNM
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BU of 1mnm by Molmil
YEAST MATALPHA2/MCM1/DNA TERNARY TRANSCRIPTION COMPLEX CRYSTAL STRUCTURE
分子名称: DNA (STE6 OPERATOR DNA), PROTEIN (MAT ALPHA-2 TRANSCRIPTIONAL REPRESSOR), PROTEIN (MCM1 TRANSCRIPTIONAL REGULATOR)
著者Tan, S, Richmond, T.J.
登録日1997-11-03
公開日1998-03-18
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of the yeast MATalpha2/MCM1/DNA ternary complex.
Nature, 391, 1998
1O4X
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BU of 1o4x by Molmil
TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
分子名称: 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', Transcription factor SOX-2, ...
著者Clore, G.M, Williams, D.C.
登録日2003-07-17
公開日2004-01-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
J.Biol.Chem., 279, 2004

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