8JY7
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8JY8
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8K1G
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8K1H
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8K4F
| DHODH in complex with compound A0 | 分子名称: | 5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine, 6-[bis(oxidanyl)methyl]-5~{H}-pyrimidine-2,4-dione, ACETATE ION, ... | 著者 | Jian, L, Sun, Q. | 登録日 | 2023-07-18 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Discovery and Optimization of Novel h DHODH Inhibitors for the Treatment of Inflammatory Bowel Disease. J.Med.Chem., 66, 2023
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8K70
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8K9I
| Structure of CUL3-RBX1-KLHL22 complex without CUL3 NA motif | 分子名称: | Cullin-3, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | 著者 | Wang, W, Ling, L, Dai, Z, Zuo, P, Yin, Y. | 登録日 | 2023-08-01 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3 KLHL22. Nat Commun, 15, 2024
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8K9K
| Full agonist-bound mu-type opioid receptor-G protein complex | 分子名称: | DAMGO, G protein subunit alpha i3, Guanine nucleotide binding protein, ... | 著者 | Hisano, T, Uchikubo-Kamo, T, Shirouzu, M, Imai, S, Kaneko, S, Shimada, I. | 登録日 | 2023-08-01 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural and dynamic insights into the activation of the mu-opioid receptor by an allosteric modulator. Nat Commun, 15, 2024
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8K9L
| Full agonist- and positive allosteric modulator-bound mu-type opioid receptor-G protein complex | 分子名称: | (2~{S})-2-(3-bromanyl-4-methoxy-phenyl)-3-(4-chlorophenyl)sulfonyl-1,3-thiazolidine, DAMGO, G protein subunit alpha i3, ... | 著者 | Hisano, T, Uchikubo-Kamo, T, Shirouzu, M, Imai, S, Kaneko, S, Shimada, I. | 登録日 | 2023-08-01 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structural and dynamic insights into the activation of the mu-opioid receptor by an allosteric modulator. Nat Commun, 15, 2024
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8KB0
| Crystal structure of 01JD-AEAIIVAMV | 分子名称: | Beta2-microglobulin, MHC class I antigen alpha chain, peptide of AIV | 著者 | Tang, Z, Zhang, N. | 登録日 | 2023-08-03 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation. Int.J.Biol.Macromol., 267, 2024
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8KB1
| Crystal structure of 11JD | 分子名称: | Beta2-microglobulin, MHC class I antigen, peptide of AIV | 著者 | Tang, Z, Zhang, N. | 登録日 | 2023-08-03 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation. Int.J.Biol.Macromol., 267, 2024
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8KFD
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8KG2
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8P5E
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8P62
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8P63
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8PIC
| Cryo EM structure of the type 3B polymorph of alpha-synuclein at low pH. | 分子名称: | Alpha-synuclein, CHLORIDE ION | 著者 | Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. | 登録日 | 2023-06-21 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | 主引用文献 | On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023
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8PIX
| Cryo EM structure of the type 3C polymorph of alpha-synuclein at low pH. | 分子名称: | Alpha-synuclein | 著者 | Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. | 登録日 | 2023-06-22 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023
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8PJK
| ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex | 分子名称: | (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 5-hydroxytryptamine receptor 1A, 6-[3-[2-(2-methoxyphenoxy)ethylamino]propoxy]-4~{H}-1,4-benzoxazin-3-one, ... | 著者 | Schneider, J, Gmeiner, P, Rasmussen, T, Boettcher, B. | 登録日 | 2023-06-23 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Discovery of a functionally selective serotonin 1A receptor agonist
for the treatment of pain To Be Published
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8PJO
| Cryo EM structure of the type 3D polymorph of alpha-synuclein E46K mutant at low pH. | 分子名称: | Alpha-synuclein, CHLORIDE ION | 著者 | Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. | 登録日 | 2023-06-23 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.31 Å) | 主引用文献 | On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023
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8PK2
| Cryo EM structure of the type 1m polymorph of alpha-synuclein | 分子名称: | Alpha-synuclein | 著者 | Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. | 登録日 | 2023-06-24 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023
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8PK4
| Cryo EM structure of the type 5A polymorph of alpha-synuclein. | 分子名称: | Alpha-synuclein | 著者 | Frey, L, Qureshi, B.M, Kwiatkowski, W, Rhyner, D, Greenwald, J, Riek, R. | 登録日 | 2023-06-24 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation Elife, 2023
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8PKM
| Befiradol-bound serotonin 5-HT1A receptor - Gi Protein Complex | 分子名称: | (2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, (3-chloranyl-4-fluoranyl-phenyl)-[4-fluoranyl-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone, 5-hydroxytryptamine receptor 1A, ... | 著者 | Schneider, J, Gmeiner, P, Hove, T.T, Rasmussen, T, Boettcher, B. | 登録日 | 2023-06-27 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Discovery of a functionally selective serotonin 1A receptor agonist
for the treatment of pain To Be Published
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8PQX
| p97 (VCP) mutant - F539A state III | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Transitional endoplasmic reticulum ATPase | 著者 | Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A. | 登録日 | 2023-07-12 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | p97 (VCP) mutant - F539A state III To Be Published
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8QJ0
| Room-temperature Serial Synchrotron Crystallography structure of Spinacia oleracea RuBisCO | 分子名称: | MAGNESIUM ION, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small subunit, ... | 著者 | Bjelcic, M, Neutze, R, Aurelius, O, Nan, J, Ursby, T. | 登録日 | 2023-09-12 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Room-temperature Serial Synchrotron Crystallography structure of Spinacia oleracea RuBisCO To Be Published
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