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5ER7
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Connexin-26 Bound to Calcium
分子名称: CALCIUM ION, Gap junction beta-2 protein
著者Purdy, M.D, Bennett, B.C, Baker, K.A, Yeager, M.J.
登録日2015-11-13
公開日2016-01-27
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (3.286 Å)
主引用文献An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels.
Nat Commun, 7, 2016
6SEG
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BU of 6seg by Molmil
Class1: CENP-A nucleosome in complex with CENP-C central region
分子名称: DNA (145-MER), Histone H2A type 2-A, Histone H2B type 1-C/E/F/G/I, ...
著者Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N.
登録日2019-07-30
公開日2019-08-14
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Embo Rep., 20, 2019
5ERL
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BU of 5erl by Molmil
Crystal structure of the epimerase SnoN in complex with Ni2+, succinate and nogalamycin RO
分子名称: NICKEL (II) ION, Nogalamycin RO, SUCCINIC ACID, ...
著者Selvaraj, B, Lindqvist, Y, Siitonen, V, Metsa-Ketela, M, Schneider, G.
登録日2015-11-14
公開日2016-05-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway.
Proc.Natl.Acad.Sci.USA, 113, 2016
6AMI
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BU of 6ami by Molmil
Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 with Trp non-covalently bound
分子名称: SODIUM ION, TRYPTOPHAN, Tryptophan synthase beta chain 1
著者Buller, A.R.
登録日2017-08-09
公開日2018-05-16
最終更新日2022-03-23
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble.
J. Am. Chem. Soc., 140, 2018
7ZW6
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BU of 7zw6 by Molmil
Oligomeric structure of SynDLP
分子名称: Slr0869 protein
著者Gewehr, L, Junglas, B, Jilly, R, Franz, J, Wenyu, E.Z, Weidner, T, Bonn, M, Sachse, C, Schneider, D.
登録日2022-05-18
公開日2023-04-19
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献SynDLP is a dynamin-like protein of Synechocystis sp. PCC 6803 with eukaryotic features.
Nat Commun, 14, 2023
7ZL9
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Crystal structure of human GPCR Niacin receptor (HCA2)
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, ...
著者Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, Han, G.W, FiBerto, J.F, Wu, L.J, Tong, J.H, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J.
登録日2022-04-14
公開日2023-04-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the human niacin receptor HCA2-G i signalling complex.
Nat Commun, 14, 2023
7ZLY
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BU of 7zly by Molmil
Crystal structure of human GPCR Niacin receptor (HCA2) expressed from Spodoptera frugiperda
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, OLEIC ACID
著者Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, FiBerto, J.F, Wu, L.J, Tong, J.H, Han, G.W, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J.
登録日2022-04-17
公開日2023-04-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the human niacin receptor HCA2-G i signalling complex.
Nat Commun, 14, 2023
7ZJL
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BU of 7zjl by Molmil
Delta SARS-CoV-2 spike protein in complex with REGN10987 Fab homologue.
分子名称: REGN10987 Fab homologue (Heavy chain), REGN10987 Fab homologue (Light chain), Spike glycoprotein
著者Pichkur, E.B, Lyukmanova, E.N, Shenkarev, Z.O.
登録日2022-04-11
公開日2023-04-19
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Delta SARS-CoV-2 spike protein in complex with REGN10987 Fab homologue.
To Be Published
7KWB
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BU of 7kwb by Molmil
Surface glycan-binding protein B from Bacteroides thetaiotaomicron
分子名称: BtSGBP-B
著者Tamura, K, Brumer, H, Van Petegem, F.
登録日2020-11-30
公開日2021-02-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota.
J.Biol.Chem., 296, 2021
5AR7
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BU of 5ar7 by Molmil
RIP2 Kinase Catalytic Domain (1 - 310) complex with Biaryl Urea
分子名称: 1-(5-TERT-BUTYL-1,2-OXAZOL-3-YL)-3-(4-PYRIDIN-4-YLOXYPHENYL)UREA, RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2
著者Charnley, A.K, Convery, M.A, Lakdawala Shah, A, Jones, E, Hardwicke, P, Bridges, A, Votta, B.J, Gough, P.J, Marquis, R.W, Bertin, J, Casillas, L.
登録日2015-09-24
公開日2015-10-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal Structures of Human Rip2 Kinase Catalytic Domain Complexed with ATP-Competitive Inhibitors: Foundations for Understanding Inhibitor Selectivity.
Bioorg.Med.Chem., 23, 2015
6IY6
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BU of 6iy6 by Molmil
Crystal structure of human cytosolic aspartyl-tRNA synthetase (DRS) in complex with glutathion-S transferase (GST) domains from Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) and glutamyl-prolyl-tRNA synthetase (EPRS)
分子名称: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Aspartate--tRNA ligase, cytoplasmic, ...
著者Park, S.H, Hahn, H, Han, B.W.
登録日2018-12-13
公開日2019-09-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The DRS-AIMP2-EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex.
Iucrj, 6, 2019
5B6I
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BU of 5b6i by Molmil
Structure of fluorinase from Streptomyces sp. MA37
分子名称: ADENOSINE, Fluorinase, METHIONINE
著者Xue, B, Robinson, R.C.
登録日2016-05-29
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Directed Evolution of a Fluorinase for Improved Fluorination Efficiency with a Non-native Substrate
Angew.Chem.Int.Ed.Engl., 55, 2016
6SE0
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BU of 6se0 by Molmil
Class 1 : CENP-A nucleosome
分子名称: DNA (145-MER), Histone H2A type 2-A, Histone H2B type 1-C/E/F/G/I, ...
著者Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N.
登録日2019-07-29
公開日2019-08-14
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Embo Rep., 20, 2019
5OI0
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BU of 5oi0 by Molmil
Crystal structure of Mycolicibacterium hassiacum glucosylglycerate hydrolase (MhGgH) in complex with serine and glycerol
分子名称: GLYCEROL, SERINE, Uncharacterized protein
著者Cereija, T.B, Macedo-Ribeiro, S, Pereira, P.J.B.
登録日2017-07-18
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Iucrj, 6, 2019
6SGR
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BU of 6sgr by Molmil
Cryo-EM structure of Escherichia coli AcrBZ and DARPin in Saposin A-nanodisc with cardiolipin
分子名称: DARPin, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrB
著者Szewczak-Harris, A, Du, D, Newman, C, Neuberger, A, Luisi, B.F.
登録日2019-08-05
公開日2020-05-13
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Interactions of a Bacterial RND Transporter with a Transmembrane Small Protein in a Lipid Environment.
Structure, 28, 2020
6J04
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BU of 6j04 by Molmil
Crystal structure of full length human LC3B delta G120 mutant (2_125)
分子名称: Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION
著者Ding, Y, Lu, B.X, Wang, Z.Y.
登録日2018-12-21
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds
Nature, 575, 2019
1O66
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BU of 1o66 by Molmil
Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase
分子名称: 3-methyl-2-oxobutanoate hydroxymethyltransferase, GLYCEROL
著者Structural GenomiX
登録日2003-10-23
公開日2003-11-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
4Q7C
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BU of 4q7c by Molmil
Structure of AF2299, a CDP-alcohol phosphotransferase
分子名称: AF2299, a CDP-alcohol phosphotransferase, CALCIUM ION, ...
著者Clarke, O.B, Sciara, G, Tomasek, D, Banerjee, S, Rajashankar, K.R, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2014-04-24
公開日2014-05-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural basis for catalysis in a CDP-alcohol phosphotransferase.
Nat Commun, 5, 2014
8A0C
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BU of 8a0c by Molmil
Capsular polysaccharide synthesis multienzyme in complex with CMP
分子名称: Bcs3, CYTIDINE-5'-MONOPHOSPHATE, GLYCEROL, ...
著者Cifuente, J.O, Schulze, J, Bethe, A, Di Domenico, V, Litschko, C, Budde, I, Eidenberger, L, Thiesler, H, Ramon-Roth, I, Berger, M, Claus, H, DAngelo, C, Marina, A, Gerardy-Schahn, R, Schubert, M, Guerin, M.E, Fiebig, T.
登録日2022-05-27
公開日2023-04-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule.
Nat.Chem.Biol., 19, 2023
6EUI
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BU of 6eui by Molmil
The GH43, Beta 1,3 Galactosidase, BT3683 with galactose
分子名称: Beta-glucanase, CALCIUM ION, beta-D-galactopyranose
著者Cartmell, A, Gilbert, H.J.
登録日2017-10-30
公開日2018-10-17
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Nat Microbiol, 3, 2018
8SDQ
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BU of 8sdq by Molmil
ATAD2 bromodomain in complex with H4S1phK5ac (res 1-15) ligand
分子名称: ATPase family AAA domain-containing protein 2, Histone H4
著者Malone, K.L, Nix, J.C, Glass, K.C.
登録日2023-04-07
公開日2024-06-05
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains.
J.Med.Chem., 67, 2024
6J35
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BU of 6j35 by Molmil
Crystal structure of ligand-free of PulA-G680L mutant from Klebsiella pneumoniae
分子名称: CALCIUM ION, GLYCEROL, MAGNESIUM ION, ...
著者Saka, N, Iwamoto, H, Takahashi, N, Mizutani, K, Mikami, B.
登録日2019-01-09
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.839 Å)
主引用文献Relationship between the induced-fit loop and the activity of Klebsiella pneumoniae pullulanase.
Acta Crystallogr D Struct Biol, 75, 2019
6AM9
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BU of 6am9 by Molmil
Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9, with Ser-bound in a predominantly closed state.
分子名称: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, SODIUM ION, Tryptophan synthase beta chain 1, ...
著者Buller, A.R, van Roye, P.
登録日2017-08-09
公開日2018-05-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble.
J. Am. Chem. Soc., 140, 2018
6AM8
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Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9 with Trp bound as E(Aex2)
分子名称: SODIUM ION, TRYPTOPHAN, Tryptophan synthase beta chain 1, ...
著者Buller, A.R, van Roye, P.
登録日2017-08-09
公開日2018-05-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble.
J. Am. Chem. Soc., 140, 2018
7E1Z
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BU of 7e1z by Molmil
Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Guo, Y.Y, Zhang, Y.Y, Yan, R.H, Huang, B.D, Ye, F.F, Wu, L.S, Chi, X.M, Zhou, Q.
登録日2021-02-04
公開日2022-06-15
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states.
Nat Commun, 13, 2022

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