8A0C

Capsular polysaccharide synthesis multienzyme in complex with CMP

Summary for 8A0C

Entry DOI	10.2210/pdb8a0c/pdb
Descriptor	Bcs3, PHOSPHATE ION, GLYCEROL, ... (6 entities in total)
Functional Keywords	bacterial capsule synthesis, biosynthetic protein
Biological source	Haemophilus influenzae
Total number of polymer chains	2
Total formula weight	276932.04
Authors	Cifuente, J.O.,Schulze, J.,Bethe, A.,Di Domenico, V.,Litschko, C.,Budde, I.,Eidenberger, L.,Thiesler, H.,Ramon-Roth, I.,Berger, M.,Claus, H.,DAngelo, C.,Marina, A.,Gerardy-Schahn, R.,Schubert, M.,Guerin, M.E.,Fiebig, T. (deposition date: 2022-05-27, release date: 2023-04-26, Last modification date: 2023-07-12)
Primary citation	Cifuente, J.O.,Schulze, J.,Bethe, A.,Di Domenico, V.,Litschko, C.,Budde, I.,Eidenberger, L.,Thiesler, H.,Ramon Roth, I.,Berger, M.,Claus, H.,D'Angelo, C.,Marina, A.,Gerardy-Schahn, R.,Schubert, M.,Guerin, M.E.,Fiebig, T. A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule. Nat.Chem.Biol., 19:865-877, 2023 Cited by PubMed: 37277468 DOI: 10.1038/s41589-023-01324-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation