5KV7
| Human cyclophilin A at 278K, Data set 9 | 分子名称: | Peptidyl-prolyl cis-trans isomerase A | 著者 | Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. | 登録日 | 2016-07-13 | 公開日 | 2016-08-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
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3D7S
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3CEP
| Structure of a tryptophan synthase quinonoid intermediate | 分子名称: | 3-hydroxy-2-iminopropanoic acid, CESIUM ION, INDOLINE, ... | 著者 | Barends, T.R.M, Domratcheva, T, Kulik, V, Blumenstein, L, Dunn, M.F, Schlichting, I. | 登録日 | 2008-02-29 | 公開日 | 2008-04-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and mechanistic implications of a tryptophan synthase quinonoid intermediate. Chembiochem, 9, 2008
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6EGV
| Sacbrood virus of honeybee | 分子名称: | minor capsid protein MiCP, structural protein VP1, structural protein VP2, ... | 著者 | Plevka, P, Prochazkova, M. | 登録日 | 2017-09-12 | 公開日 | 2018-07-18 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Virion structure and genome delivery mechanism of sacbrood honeybee virus. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4P5O
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5KKN
| Crystal structure of human ACC2 BC domain in complex with ND-646, the primary amide of ND-630 | 分子名称: | 2-[1-[(2~{R})-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-bis(oxidanylidene)thieno[2,3-d]pyrimidin-3-yl]-2-methyl-propanamide, Acetyl-CoA carboxylase 2 | 著者 | Wang, R, Paul, D, Tong, L. | 登録日 | 2016-06-22 | 公開日 | 2016-07-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proc.Natl.Acad.Sci.USA, 113, 2016
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7SEI
| Glucose-6-phosphate 1-dehydrogenase (K403Q) | 分子名称: | Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Mathews, I.I, Garcia, A.A, Wakatsuki, S, Mochly-Rosen, D. | 登録日 | 2021-09-30 | 公開日 | 2022-08-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants. J.Biol.Chem., 298, 2022
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6EHF
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6IJ4
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1EAN
| THE RUNX1 Runt domain at 1.70A resolution: A structural switch and specifically bound chloride ions modulate DNA binding | 分子名称: | CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1 | 著者 | Backstrom, S, Wolf-Watz, M, Grundstrom, C, Hard, T, Grundstrom, T, Sauer, U.H. | 登録日 | 2001-07-13 | 公開日 | 2002-09-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Runx1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding J.Mol.Biol., 322, 2002
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6IG7
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1EUO
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6EJQ
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8SUT
| Crystal structure of YisK from Bacillus subtilis in complex with reaction product 4-Hydroxy-2-oxoglutaric acid | 分子名称: | (2~{R})-2-oxidanyl-4-oxidanylidene-pentanedioic acid, Fumarylacetoacetate hydrolase family protein, MANGANESE (II) ION | 著者 | Krieger, I.V, Chemelewski, V, Guo, T, Sperber, A, Herman, J, Sacchettini, J.C. | 登録日 | 2023-05-13 | 公開日 | 2023-11-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Bacillus subtilis YisK possesses oxaloacetate decarboxylase activity and exhibits Mbl-dependent localization. J.Bacteriol., 206, 2024
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8SUU
| Crystal structure of YisK from Bacillus subtilis in apo form | 分子名称: | Fumarylacetoacetate hydrolase family protein, MANGANESE (II) ION | 著者 | Krieger, I.V, Chemelewski, V, Guo, T, Sperber, A, Herman, J, Sacchettini, J.C. | 登録日 | 2023-05-13 | 公開日 | 2023-11-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Bacillus subtilis YisK possesses oxaloacetate decarboxylase activity and exhibits Mbl-dependent localization. J.Bacteriol., 206, 2024
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6EO7
| X-ray structure of the complex between human alpha-thrombin and modified 15-mer DNA aptamer containing 5-(3-(acetamide-N-yl)-1-propen-1-yl)-2'-deoxyuridine residue | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GA68B2 - MODIFIED HUMAN THROMBIN BINDING APTAMER, ... | 著者 | Dolot, R.M, Nawrot, B, Yang, X. | 登録日 | 2017-10-09 | 公開日 | 2017-10-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity. Nucleic Acids Res., 46, 2018
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6EOO
| DPP8 - Apo, space group 20 | 分子名称: | Dipeptidyl peptidase 8 | 著者 | Ross, B.R, Huber, R. | 登録日 | 2017-10-10 | 公開日 | 2018-02-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5KO1
| Pseudokinase Domain of MLKL bound to Compound 4. | 分子名称: | Mixed lineage kinase domain-like protein, [(1~{R})-2-[(4-fluorophenyl)amino]-2-oxidanylidene-1-phenyl-ethyl] 3-azanylpyrazine-2-carboxylate | 著者 | Marcotte, D.J. | 登録日 | 2016-06-29 | 公開日 | 2016-11-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis. Plos One, 11, 2016
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1EA4
| TRANSCRIPTIONAL REPRESSOR COPG/22bp dsDNA COMPLEX | 分子名称: | DNA (5'-D(*TP*AP*AP*CP*CP*GP*TP*GP *CP*AP*CP*TP*CP*AP*AP*TP*GP*CP*AP*AP*TP*C)-3'), DNA(5'-D(*AP*GP*AP*TP*TP*GP*CP*AP*TP *TP*GP*AP*GP*TP*GP*CP*AP*CP*GP*GP*TP*T)-3'), TRANSCRIPTIONAL REPRESSOR COPG | 著者 | Gomis-Rueth, F.X, Costa, M, Sola, M, Acebo, P, Eritja, R, Espinosa, M, Solar, G.D, Coll, M. | 登録日 | 2000-11-05 | 公開日 | 2001-07-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Plasmid Transcriptional Repressor Copg Oligomerises to Render Helical Superstructures Unbound and in Complexes with Oligonucleotides J.Mol.Biol., 310, 2001
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6IPV
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7SC4
| filamin complex-1 | 分子名称: | Filamin-A/Integrin alpha-IIb light chain, form 2 chimera, SULFATE ION | 著者 | Liu, J, Qin, J. | 登録日 | 2021-09-27 | 公開日 | 2023-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage. Blood, 141, 2023
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6IQC
| Wild-type Programmed Cell Death 5 protein from Sulfolobus solfataricus | 分子名称: | DNA-binding protein SSO0352, SODIUM ION, TETRAETHYLENE GLYCOL | 著者 | Chen, C.Y, Lin, K.F, Hsu, C.Y, Tsai, M.J. | 登録日 | 2018-11-06 | 公開日 | 2019-02-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Crystal structure of the programmed cell death 5 protein from Sulfolobus solfataricus. Acta Crystallogr F Struct Biol Commun, 75, 2019
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5KXK
| Hen Egg White Lysozyme at 100K, Data set 1 | 分子名称: | ACETATE ION, CHLORIDE ION, Lysozyme C, ... | 著者 | Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. | 登録日 | 2016-07-20 | 公開日 | 2016-09-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.198 Å) | 主引用文献 | Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
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8STW
| K384N HUMAN CYSTATHIONINE BETA-SYNTHASE (delta 411-551) | 分子名称: | Cystathionine beta-synthase, K384N variant, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Mascarenhas, R, Roman, J, Banerjee, R. | 登録日 | 2023-05-11 | 公開日 | 2023-11-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Disease-causing cystathionine beta-synthase linker mutations impair allosteric regulation. J.Biol.Chem., 299, 2023
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6IQO
| Se-Met L45M Programmed Cell Death 5 protein from Sulfolobus solfataricus | 分子名称: | DNA-binding protein SSO0352, NONAETHYLENE GLYCOL | 著者 | Chen, C.Y, Lin, K.F, Hsu, C.Y, Tsai, M.J. | 登録日 | 2018-11-08 | 公開日 | 2019-02-20 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Crystal structure of the programmed cell death 5 protein from Sulfolobus solfataricus. Acta Crystallogr F Struct Biol Commun, 75, 2019
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