PDB: 35712 件ウェブページステータス検索Chemie searchBIRD

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8OR9	Human holo aromatic L-amino acid decarboxylase (AADC) native structure at physiological pH 分子名称: Dopa decarboxylase (Aromatic L-amino acid decarboxylase), PYRIDOXAL-5'-PHOSPHATE, TETRAETHYLENE GLYCOL 著者 Bisello, G, Perduca, M, Bertoldi, M. 登録日 2023-04-13 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: Implication in aromatic amino acid decarboxylase deficiency. Protein Sci., 32, 2023
6XIX	Triuret Hydrolase (TrtA) from Herbaspirillum sp. BH-1 分子名称: BETA-MERCAPTOETHANOL, Cysteine hydrolase 著者 Tassoulas, L.T, Elias, M.H, Wackett, L.P. 登録日 2020-06-22 公開日 2020-11-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of an ultraspecific triuret hydrolase (TrtA) establishes the triuret biodegradation pathway. J.Biol.Chem., 296, 2020
8EQH	The crystal structure of 14-3-3 Beta containing 3-nitrotyrosine at position Y213 分子名称: 14-3-3 protein beta/alpha 著者 Zhu, P, Cooley, R.B. 登録日 2022-10-07 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Genetic encoding of 3-nitro-tyrosine reveals the impacts of 14-3-3 nitration on client binding and dephosphorylation. Protein Sci., 32, 2023
5LKR	Human Butyrylcholinesterase complexed with N-Propargyliperidines 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cholinesterase, ... 著者 Coquelle, N, Knez, D, Colletier, J.P, Gobec, S. 登録日 2016-07-23 公開日 2016-12-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents. Bioorg. Med. Chem., 25, 2017
8EZH	A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase R98A/R100A variant modeled with sulfite-NPN adduct 分子名称: (4S)-5-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-4-sulfo-1,4-dihydropyridine-3-carbothioic S-acid, 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Gatreddi, S, Hausinger, R.P, Hu, J. 登録日 2022-10-31 公開日 2023-01-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Irreversible inactivation of lactate racemase by sodium borohydride reveals reactivity of the nickel-pincer nucleotide cofactor. Acs Catalysis, 13, 2023
6XJE	Triuret Hydrolase (TrtA) from Herbaspirillum sp. BH-1 C162S bound with triuret 分子名称: 1,2-ETHANEDIOL, Cysteine hydrolase, tricarbonodiimidic diamide 著者 Tassoulas, L.T, Elias, M.H, Wackett, L.P. 登録日 2020-06-23 公開日 2020-11-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Discovery of an ultraspecific triuret hydrolase (TrtA) establishes the triuret biodegradation pathway. J.Biol.Chem., 296, 2020
5WFV	Kelch domain of human Keap1 bound to Nrf2 ETGE peptide 分子名称: Kelch-like ECH-associated protein 1, Nrf2 ETGE peptide, SULFATE ION 著者 Carolan, J.P, Lynch, A.J, Allen, K.N. 登録日 2017-07-12 公開日 2018-09-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2). Biochemistry, 59, 2020
6X9L	Crystal Structure of Aldehyde Dehydrogenase C (AldC) mutant (C291A) from Pseudomonas syringae in complexed with NAD+ and Octanal 分子名称: Aldehyde dehydrogenase family protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OCTANAL 著者 Lee, S.G, Jez, J.M. 登録日 2020-06-03 公開日 2020-09-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 The plant pathogen enzyme AldC is a long-chain aliphatic aldehyde dehydrogenase. J.Biol.Chem., 295, 2020
5LVX	Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator 分子名称: 11-[(2~{R})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid, 11-[(2~{S})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Zheng, J, Chen, L, Skinner, O.S, Lansbury, P, Skerlj, R, Mrosek, M, Heunisch, U, Krapp, S, Weigand, S, Charrow, J, Schwake, M, Kelleher, N.L, Silverman, R.B, Krainc, D. 登録日 2016-09-14 公開日 2017-10-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 beta-Glucocerebrosidase Modulators Promote Dimerization of beta-Glucocerebrosidase and Reveal an Allosteric Binding Site. J. Am. Chem. Soc., 140, 2018
5AIO	Crystal structure of t131 N-terminal TPR array 分子名称: TRANSCRIPTION FACTOR TAU 131 KDA SUBUNIT 著者 Male, G, Glatt, S, Mueller, C.W. 登録日 2015-02-16 公開日 2015-06-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.148 Å) 主引用文献 Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly. Nat Commun, 6, 2015
5WHO	Kelch domain of human Keap1 bound to small molecule inhibitor fragment: 4-oxo-4H-1-benzopyran-2-carboxylic acid 分子名称: 4-oxo-4H-1-benzopyran-2-carboxylic acid, Kelch-like ECH-associated protein 1, SULFATE ION 著者 Carolan, J.P, Lynch, A.J, Allen, K.N. 登録日 2017-07-17 公開日 2018-09-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2). Biochemistry, 59, 2020
5M12	Structure of GH36 alpha-galactosidase from Thermotoga maritima in complex with intact cyclopropyl-carbasugar. 分子名称: (1~{R},2~{S},3~{S},4~{R},5~{S},6~{S})-5-[3,5-bis(fluoranyl)phenoxy]-1-(hydroxymethyl)bicyclo[4.1.0]heptane-2,3,4-triol, Alpha-galactosidase, MAGNESIUM ION, ... 著者 Pengelly, R, Gloster, T. 登録日 2016-10-07 公開日 2016-11-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars. Angew.Chem.Int.Ed.Engl., 55, 2016
1EL2	SOLUTION STRUCTURE OF A MODIFIED HUMAN TELOMERE FRAGMENT (STRUCTURE "A") 分子名称: 5'-D(*CP*CP*CP*TP*AP*AP*(5CM)P*CP*CP*TP*AP*AP*CP*CP*CP*UP*AP*AP*CP*CP*CP*T)-3' 著者 Phan, A.T, Gueron, M, Leroy, J.-L. 登録日 2000-03-13 公開日 2000-03-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The solution structure and internal motions of a fragment of the cytidine-rich strand of the human telomere. J.Mol.Biol., 299, 2000
8ORA	Human holo aromatic L-amino acid decarboxylase (AADC) external aldimine with L-Dopa methylester 分子名称: Dopa decarboxylase (Aromatic L-amino acid decarboxylase), PYRIDOXAL-5'-PHOSPHATE, TETRAETHYLENE GLYCOL, ... 著者 Bisello, G, Perduca, M, Bertoldi, M. 登録日 2023-04-13 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: Implication in aromatic amino acid decarboxylase deficiency. Protein Sci., 32, 2023
6XE0	Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment) 分子名称: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Washburn, R, Zuber, P, Sun, M, Hashem, Y, Shen, B, Li, W, Harvey, S, Acosta-Reyes, F.J, Knauer, S.H, Frank, J, Gottesman, M.E. 登録日 2020-06-11 公開日 2020-07-29 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex. Iscience, 23, 2020
1EOP	ECORV BOUND TO COGNATE DNA 分子名称: DNA (5'-D(*GP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*C)-3'), TYPE II RESTRICTION ENZYME ECORV 著者 Horton, N.C, Perona, J.J. 登録日 2000-03-23 公開日 2000-04-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystallographic snapshots along a protein-induced DNA-bending pathway. Proc.Natl.Acad.Sci.USA, 97, 2000
6X9O	High resolution cryoEM structure of huntingtin in complex with HAP40 分子名称: 40-kDa huntingtin-associated protein, Huntingtin 著者 Harding, R.J, Deme, J.C, Lea, S.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) 登録日 2020-06-03 公開日 2020-06-17 最終更新日 2022-03-30 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1. Commun Biol, 4, 2021
8F5W	Dihydropyrimidine Dehydrogenase (DPD) C671S Mutant Soaked with Dihydrothymine and NADPH Quasi-Anaerobically 分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, Dihydropyrimidine dehydrogenase [NADP(+)], FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Kaley, N, Smith, M, Forouzesh, D, Liu, D, Moran, G. 登録日 2022-11-15 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Mammalian dihydropyrimidine dehydrogenase: Added mechanistic details from transient-state analysis of charge transfer complexes. Arch.Biochem.Biophys., 736, 2023
8EYO	Crystal Structure of Human Mitochondrial NADP+ Malic Enzyme 3 with NADP bound 分子名称: CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent malic enzyme, ... 著者 Shaffer, P.L, Grell, T.A.J, Mason, M, Thompson, A.A, Riley, D, Wagner, M.V, Steele, R, Ortiz-Meoz, R, Wadia, J, Sharma, S, Yu, X. 登録日 2022-10-28 公開日 2023-02-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer. Heliyon, 8, 2022
4XOU	Crystal structure of the SR Ca2+-ATPase in the Ca2-E1-MgAMPPCP form determined by serial femtosecond crystallography using an X-ray free-electron laser. 分子名称: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... 著者 Bublitz, M, Nass, K, Drachmann, N.D, Markvardsen, A.J, Gutmann, M.J, Barends, T.R.M, Mattle, D, Shoeman, R.L, Doak, R.B, Boutet, S, Messerschmidt, M, Seibert, M.M, Williams, G.J, Foucar, L, Reinhard, L, Sitsel, O, Gregersen, J.L, Clausen, J.D, Boesen, T, Gotfryd, K, Wang, K.-T, Olesen, C, Moller, J.V, Nissen, P, Schlichting, I. 登録日 2015-01-16 公開日 2015-06-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser. Iucrj, 2, 2015
6XDT	Carbonmonoxy hemoglobin in complex with the antisickling agent methyl 5-((2-formyl-4-methoxyphenoxy)methyl)picolinate 分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Pagare, P.P, Safo, M.K, Musayev, F.N. 登録日 2020-06-11 公開日 2020-12-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Exploration of Structure-Activity Relationship of Aromatic Aldehydes Bearing Pyridinylmethoxy-Methyl Esters as Novel Antisickling Agents. J.Med.Chem., 63, 2020
5LDW	Structure of mammalian respiratory Complex I, class1 分子名称: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Vinothkumar, K.R, Zhu, J, Hirst, J. 登録日 2016-06-28 公開日 2016-09-07 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (4.27 Å) 主引用文献 Structure of mammalian respiratory complex I. Nature, 536, 2016
5LXW	Atomic resolution X-ray crystal structure of cisplatin bound to hen egg white lysozyme stored for 5 years on the shelf 分子名称: AMMONIA, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Helliwell, J.R. 登録日 2016-09-22 公開日 2016-10-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Atomic resolution X-ray crystal structure of cisplatin bound to hen egg white lysozyme stored for 5 years 'on the shelf' Zenodo, 2016
8F6N	Dihydropyrimidine Dehydrogenase (DPD) C671S Mutant Soaked with Thymine Quasi-Anaerobically 分子名称: Dihydropyrimidine dehydrogenase [NADP(+)], FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Kaley, N, Smith, M, Forouzesh, D, Liu, D, Moran, G. 登録日 2022-11-16 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Mammalian dihydropyrimidine dehydrogenase: Added mechanistic details from transient-state analysis of charge transfer complexes. Arch.Biochem.Biophys., 736, 2023
5WUQ	Crystal structure of SigW in complex with its anti-sigma RsiW, a zinc binding form 分子名称: Anti-sigma-W factor RsiW, ECF RNA polymerase sigma factor SigW, ZINC ION 著者 Devkota, S.R, Kwon, E, Ha, S.C, Kim, D.Y. 登録日 2016-12-20 公開日 2017-03-29 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural insights into the regulation of Bacillus subtilis SigW activity by anti-sigma RsiW PLoS ONE, 12, 2017

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