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2J1W
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Human p53 core domain mutant M133L-V143A-V203A-N239Y-N268D
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2006-08-15
公開日2006-09-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for Understanding Oncogenic P53 Mutations and Designing Rescue Drugs.
Proc.Natl.Acad.Sci.USA, 103, 2006
2PE5
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BU of 2pe5 by Molmil
Crystal Structure of the Lac Repressor bound to ONPG in repressed state
分子名称: 2-nitrophenyl beta-D-galactopyranoside, DNA (5'-D(*DAP*DAP*DTP*DTP*DGP*DTP*DGP*DAP*DGP*DCP*DGP*DCP*DTP*DCP*DAP*DCP*DAP*DAP*DTP*DT)-3'), Lactose operon repressor
著者Daber, R, Stayrook, S.E, Rosenberg, A, Lewis, M.
登録日2007-04-02
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural analysis of lac repressor bound to allosteric effectors
J.Mol.Biol., 370, 2007
3O3K
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BU of 3o3k by Molmil
Crystal structure of AF1382 from Archaeoglobus fulgidus
分子名称: Uncharacterized protein AF_1382
著者Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Xu, H, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2010-07-24
公開日2010-08-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal.
Acta Crystallogr.,Sect.D, 68, 2012
4LFU
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BU of 4lfu by Molmil
Crystal structure of Escherichia coli SdiA in the space group C2
分子名称: CHLORIDE ION, Regulatory protein SdiA, TETRAETHYLENE GLYCOL
著者Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K.
登録日2013-06-27
公開日2014-03-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
4LGW
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BU of 4lgw by Molmil
Crystal structure of Escherichia coli SdiA in the space group P6522
分子名称: GLYCEROL, Regulatory protein SdiA
著者Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K.
登録日2013-06-28
公開日2014-03-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor
Acta Crystallogr.,Sect.D, 70, 2014
1M0I
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BU of 1m0i by Molmil
Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site
分子名称: SULFATE ION, endodeoxyribonuclease I
著者Hadden, J.M, Declais, A.C, Phillips, S.E, Lilley, D.M.
登録日2002-06-13
公開日2002-12-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I
Embo J., 21, 2002
5LY0
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BU of 5ly0 by Molmil
Crystal structure of LOB domain of Ramosa2 from Wheat
分子名称: LOB family transfactor Ramosa2.1, ZINC ION
著者Wei, X.-B, Zhang, B, Chen, W.-F, Fan, S.-H, Rety, S, Xi, X.-G.
登録日2016-09-23
公開日2017-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.877 Å)
主引用文献Structural analysis reveals a "molecular calipers" mechanism for a LATERAL ORGAN BOUNDARIES DOMAIN transcription factor protein from wheat.
J. Biol. Chem., 294, 2019
5MBV
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BU of 5mbv by Molmil
Cryo-EM structure of Lambda Phage protein GamS bound to RecBCD.
分子名称: Host-nuclease inhibitor protein gam, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ...
著者Wilkinson, M, Chaban, Y, Wigley, D.B.
登録日2016-11-08
公開日2017-01-11
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones.
Elife, 5, 2016
5LJ4
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BU of 5lj4 by Molmil
Crystal structure of DNA duplex containing ZP base pair
分子名称: CALCIUM ION, ODN2
著者Agnew, C.R.J, Brady, R.L.
登録日2016-07-17
公開日2017-05-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural Basis of the Mispairing of an Artificially Expanded Genetic Information System
Chem, 1, 2016
1M0D
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BU of 1m0d by Molmil
Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site and Bound Manganese Ions
分子名称: Endodeoxyribonuclease I, MANGANESE (II) ION, SULFATE ION
著者Hadden, J.M, Declais, A.C, Phillips, S.E, Lilley, D.M.
登録日2002-06-12
公開日2002-07-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I.
EMBO J., 21, 2002
4TV7
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BU of 4tv7 by Molmil
Crystal structure of Bacillus subtilis GabR at 2.05 Angstroms resolution
分子名称: HTH-type transcriptional regulatory protein GabR
著者Goto, M, Okuda, K, Yoshimura, T.
登録日2014-06-26
公開日2014-12-24
最終更新日2020-01-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Role of the aminotransferase domain in Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator
Mol. Microbiol., 95, 2015
5LRR
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BU of 5lrr by Molmil
The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione
分子名称: GLUTATHIONE, HYDROGENPHOSPHATE ION, Listeriolysin positive regulatory factor A, ...
著者Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E.
登録日2016-08-19
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.171 Å)
主引用文献Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
4F8D
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BU of 4f8d by Molmil
Crystal Structure of an R46A mutant of the Restriction-Modification Controller Protein C.Esp1396I (Monoclinic Form)
分子名称: Regulatory protein, SODIUM ION, SULFATE ION
著者Martin, R.N.A, McGeehan, J.E, Kneale, G.G.
登録日2012-05-17
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I.
Plos One, 9, 2014
4K2E
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BU of 4k2e by Molmil
HlyU from Vibrio cholerae N16961
分子名称: Transcriptional activator HlyU
著者Mukherjee, D, Datta, A.B, Chakrabarti, P.
登録日2013-04-09
公開日2014-04-30
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of HlyU, the hemolysin gene transcription activator, from Vibrio cholerae N16961 and functional implications.
Biochim.Biophys.Acta, 1844, 2014
3D1N
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BU of 3d1n by Molmil
Structure of human Brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter
分子名称: 5'-D(*DAP*DGP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DA)-3', 5'-D(*DTP*DTP*DAP*DTP*DTP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DCP*DT)-3', POU domain, ...
著者Pereira, J.H, Ha, S.C, Kim, S.-H.
登録日2008-05-06
公開日2009-05-26
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of human Brn-5 transcription factor in complex with CRH gene promoter.
J.Struct.Biol., 167, 2009
4FBI
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BU of 4fbi by Molmil
Crystal Structure of an R46A mutant of the Restriction-Modification Controller Protein C.Esp1396I (Trigonal Form)
分子名称: GLYCEROL, Regulatory protein
著者Martin, R.N.A, McGeehan, J.E, Kneale, G.G.
登録日2012-05-23
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I.
Plos One, 9, 2014
4FN3
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BU of 4fn3 by Molmil
Crystal Structure of an S52A mutant of the Restriction-Modification Controller Protein C.Esp1396I
分子名称: Regulatory protein, SULFATE ION
著者Martin, R.N.A, McGeehan, J.E, Kneale, G.G.
登録日2012-06-19
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural and Mutagenic Analysis of the RM Controller Protein C.Esp1396I.
Plos One, 9, 2014
4HK1
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BU of 4hk1 by Molmil
Crystal Structure of PCNA from Drosophila melanogaster
分子名称: Proliferating cell nuclear antigen
著者Wang, K, Shi, Z.B, Zhou, Z.C.
登録日2012-10-14
公開日2013-04-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structure of PCNA from Drosophila melanogaster.
Acta Crystallogr.,Sect.F, 69, 2013
3FBR
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BU of 3fbr by Molmil
structure of HipA-amppnp-peptide
分子名称: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase toxin HipA, peptide of EF-Tu
著者Schumacher, M.A.
登録日2008-11-19
公開日2009-02-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
3C3W
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BU of 3c3w by Molmil
Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR
分子名称: SULFATE ION, TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR
著者Wisedchaisri, G, Wu, M, Sherman, D.R, Hol, W.G.J.
登録日2008-01-28
公開日2008-04-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation
J.Mol.Biol., 378, 2008
4DBV
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BU of 4dbv by Molmil
GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE MUTANT WITH LEU 33 REPLACED BY THR, THR 34 REPLACED BY GLY, ASP 36 REPLACED BY GLY, LEU 187 REPLACED BY ALA, AND PRO 188 REPLACED BY SER COMPLEXED WITH NADP+
分子名称: GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
著者Didierjean, C, Rahuel-Clermont, S, Vitoux, B, Dideberg, O, Branlant, G, Aubry, A.
登録日1997-01-06
公開日1997-07-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A crystallographic comparison between mutated glyceraldehyde-3-phosphate dehydrogenases from Bacillus stearothermophilus complexed with either NAD+ or NADP+.
J.Mol.Biol., 268, 1997
2G7O
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BU of 2g7o by Molmil
Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM
分子名称: Protein traM
著者Lu, J, Edwards, R.A, Wong, J.J, Manchak, J, Scott, P.G, Frost, L.S, Glover, J.N.
登録日2006-02-28
公開日2006-06-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM.
Embo J., 25, 2006
6DXL
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BU of 6dxl by Molmil
Linked amidobenzimidazole STING agonist
分子名称: 1,1'-(butane-1,4-diyl)bis{2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-1H-benzimidazole-5-carboxamide}, CALCIUM ION, Stimulator of interferon protein
著者Concha, N.O.
登録日2018-06-29
公開日2018-11-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature, 564, 2018
2J6W
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R164N mutant of the RUNX1 Runt domain
分子名称: CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1
著者Grembecka, J, Zhe, L, Lukasik, S.M, Liu, Y, Bielnicka, I, Bushweller, J.H, Speck, N.A.
登録日2006-10-04
公開日2007-10-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Mutation in the S-Switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for Cbfbeta Regulation.
J.Mol.Biol., 364, 2006
3DNT
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BU of 3dnt by Molmil
structures of MDT proteins
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein hipA, ...
著者Schumacher, M.A.
登録日2008-07-02
公開日2009-01-27
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009

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