2O6G
| |
4GO1
| Crystal Structure of full length transcription repressor LsrR from E. coli. | 分子名称: | GLYCEROL, Transcriptional regulator LsrR | 著者 | Wu, M, Tao, Y, Liu, X, Zang, J. | 登録日 | 2012-08-17 | 公開日 | 2013-04-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Basis for Phosphorylated Autoinducer-2 Modulation of the Oligomerization State of the Global Transcription Regulator LsrR from Escherichia coli J.Biol.Chem., 288, 2013
|
|
8CX2
| Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 2 | 分子名称: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | 著者 | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | 登録日 | 2022-05-19 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature, 615, 2023
|
|
8CX0
| Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC monomeric complex | 分子名称: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | 著者 | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | 登録日 | 2022-05-19 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature, 615, 2023
|
|
8CX1
| Cryo-EM structure of human APOBEC3G/HIV-1 Vif/CBFbeta/ELOB/ELOC dimeric complex in State 1 | 分子名称: | Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, Elongin-B, ... | 著者 | Li, Y, Langley, C, Azumaya, C.M, Echeverria, I, Chesarino, N.M, Emerman, M, Cheng, Y, Gross, J.D. | 登録日 | 2022-05-19 | 公開日 | 2023-02-15 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The structural basis for HIV-1 Vif antagonism of human APOBEC3G. Nature, 615, 2023
|
|
7OUF
| Structure of the STLV intasome:B56 complex bound to the strand-transfer inhibitor XZ450 | 分子名称: | 4-azanyl-~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-6-[3-(dimethylamino)-3-oxidanylidene-propyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide, DNA (5'-D(*AP*CP*TP*GP*TP*GP*TP*TP*TP*GP*GP*CP*GP*CP*TP*TP*CP*TP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*AP*GP*AP*AP*GP*CP*GP*CP*CP*AP*AP*AP*CP*AP*CP*A)-3'), ... | 著者 | Barski, M.S, Ballandras-Colas, A, Cronin, N.B, Pye, V.E, Cherepanov, P, Maertens, G.N. | 登録日 | 2021-06-11 | 公開日 | 2021-08-18 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures. Nat Commun, 12, 2021
|
|
8F2I
| P53 monomer structure | 分子名称: | Cellular tumor antigen p53 | 著者 | Solares, M, Kelly, D.F. | 登録日 | 2022-11-08 | 公開日 | 2022-11-23 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | High-Resolution Imaging of Human Cancer Proteins Using Microprocessor Materials. Chembiochem, 23, 2022
|
|
8F2H
| |
4OOI
| |
4LY2
| X-ray crystal structure of the ruthenium complex [Ru(phen)2(dppz)]2+ bound to d(TCGGTACCGA) | 分子名称: | BARIUM ION, DNA, Lambda-Ru(phen)2(dppz) complex | 著者 | Niyazi, H, Teixeira, S, Mitchell, E, Forsyth, T, Cardin, C. | 登録日 | 2013-07-30 | 公開日 | 2014-09-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | X-ray crystal structure of the ruthenium complex [Ru(phen)2(dppz)]2+ bound to d(TCGGTACCGA) To be Published
|
|
4M3V
| X-ray crystal structure of the ruthenium complex [Ru(Tap)2(dppz-{Me2})]2+ bound to d(TCGGTACCGA) | 分子名称: | (11,12-dimethyldipyrido[3,2-a:2',3'-c]phenazine-kappa~2~N~4~,N~5~)[bis(pyrazino[2,3-f]quinoxaline-kappa~2~N~1~,N~10~)]ruthenium(2+), BARIUM ION, DNA decamer sequence | 著者 | Niyazi, H, Teixeira, S, Mitchell, E, Forsyth, T, Cardin, C. | 登録日 | 2013-08-06 | 公開日 | 2014-09-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | X-ray crystal structure of the ruthenium complex [Ru(Tap)2(dppz-{Me2})]2+ bound to d(TCGGTACCGA) To be Published
|
|
2J1Z
| |
4LP0
| Crystal structure of a topoisomerase ATP inhibitor | 分子名称: | 6'-[(ethylcarbamoyl)amino]-4'-[4-(trifluoromethyl)-1,3-thiazol-2-yl]-3,3'-bipyridine-5-carboxylic acid, Topoisomerase IV subunit B | 著者 | Basarab, G.S, Manchester, J.I, Bist, S, Boriack-Sjodin, P.A, Dangel, B, Illingsworth, R, Uria-Nickelsen, M, Sherer, B.A, Sriram, S, Eakin, A.E. | 登録日 | 2013-07-14 | 公開日 | 2013-11-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents. J.Med.Chem., 56, 2013
|
|
4LPB
| Crystal structure of a topoisomerase ATPase inhibitor | 分子名称: | 1-ethyl-3-{5'-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]-3,3'-bipyridin-6-yl}urea, Topoisomerase IV subunit B | 著者 | Boriack-Sjodin, A. | 登録日 | 2013-07-15 | 公開日 | 2013-10-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents. J.Med.Chem., 56, 2013
|
|
4O8B
| Crystal structure of transcriptional regulator BswR | 分子名称: | Uncharacterized protein | 著者 | Ye, F.Z, Wang, C, Kumar, V, Zhang, L.H, Gao, Y.G. | 登録日 | 2013-12-26 | 公開日 | 2014-02-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA rsmZ. Nucleic Acids Res., 42, 2014
|
|
2J21
| |
2J1Y
| |
2J20
| |
4RBR
| Crystal structure of Repressor of Toxin (Rot), a central regulator of Staphylococcus aureus virulence | 分子名称: | CHLORIDE ION, HTH-type transcriptional regulator rot | 著者 | Killikelly, A, Jakoncic, J, Sampson, J.M, Kong, X.-P. | 登録日 | 2014-09-12 | 公開日 | 2014-11-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure-Based Functional Characterization of Repressor of Toxin (Rot), a Central Regulator of Staphylococcus aureus Virulence. J.Bacteriol., 197, 2015
|
|
7PNL
| Complex between monomolecular human telomeric G-quadruplex and a sulfonamide derivative of the natural alkaloid Berberine | 分子名称: | 4-[[1-[3-[(17-methoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15,17,19-octaen-16-yl)oxy]propyl]triazol-4-yl]methoxy]benzenesulfonamide, G-guadruplex DNA (23-mer), POTASSIUM ION | 著者 | Bazzicalupi, C, Gratteri, P, Petreni, A, Nocentini, A. | 登録日 | 2021-09-07 | 公開日 | 2022-09-21 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Development of a multi-targeted chemotherapeutic approach based on G-quadruplex stabilisation and carbonic anhydrase inhibition. J Enzyme Inhib Med Chem, 39, 2024
|
|
2J1X
| |
4UIG
| |
8U16
| The ternary complex structure of DDB1-CRBN-SALL4(ZF1,2)-short bound to Pomalidomide | 分子名称: | 1,2-ETHANEDIOL, DNA damage-binding protein 1, Protein cereblon, ... | 著者 | Clifton, M.C, Ma, X, Ornelas, E. | 登録日 | 2023-08-30 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon. Sci Rep, 13, 2023
|
|
8TL6
| Cryo-EM structure of DDB1deltaB-DDA1-DCAF5 | 分子名称: | DDB1- and CUL4-associated factor 5, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1 | 著者 | Yue, H, Hunkeler, M, Roy Burman, S.S, Fischer, E.S. | 登録日 | 2023-07-26 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | 主引用文献 | Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF. Nature, 628, 2024
|
|
8TZX
| Ternary complex structure of Cereblon-DDB1 bound to WIZ(ZF7) and the molecular glue dWIZ-1 | 分子名称: | (3S)-3-(5-{(1R)-1-[(2R)-1-ethylpiperidin-2-yl]ethoxy}-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione, 1,2-ETHANEDIOL, DNA damage-binding protein 1, ... | 著者 | Clifton, M.C, Ma, X, Ornelas, E. | 登録日 | 2023-08-28 | 公開日 | 2024-07-10 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction. Science, 385, 2024
|
|