PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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6YQ0	Promiscuous Reductase LugOII Catalyzes Keto-reduction at C1 during Lugdunomycin Biosynthesis 分子名称: (3~{R})-8-methoxy-3-methyl-3-oxidanyl-2,4-dihydrobenzo[a]anthracene-1,7,12-trione, 1,2-ETHANEDIOL, Monooxygenase, ... 著者 Xiao, X, Elsayed, S.S, Wu, C, van der Heul, H, Prota, A, Huang, J, Guo, R, Abrahams, J.P, van Wezel, G.P. 登録日 2020-04-16 公開日 2020-09-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Functional and Structural Insights into a Novel Promiscuous Ketoreductase of the Lugdunomycin Biosynthetic Pathway. Acs Chem.Biol., 15, 2020
7AYY	Structure of the human 8-oxoguanine DNA Glycosylase hOGG1 in complex with activator TH10785 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, N-glycosylase/DNA lyase, ... 著者 Masuyer, G, Davies, J.R, Stenmark, P. 登録日 2020-11-13 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science, 376, 2022
7AZ0	Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with TH12161 分子名称: 2-cyclopropyl-~{N}-(4-iodophenyl)quinazolin-4-amine, N-glycosylase/DNA lyase, NICKEL (II) ION 著者 Davies, J.R, Masuyer, G, Stenmark, P. 登録日 2020-11-13 公開日 2022-06-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science, 376, 2022
6YNH	GAPDH purified from the supernatant of HEK293F cells: crystal form 4 of 4 分子名称: 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Glyceraldehyde-3-phosphate dehydrogenase 著者 Roversi, P, Lia, A. 登録日 2020-04-13 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.621 Å) 主引用文献 Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid. Wellcome Open Res, 5, 2020
6YDI	XFEL structure of the Soluble methane monooxygenase hydroxylase and regulatory subunit complex, from Methylosinus trichosporium OB3b, diferrous state 分子名称: FE (II) ION, GLYCEROL, Methane monooxygenase, ... 著者 Srinivas, V, Hogbom, M. 登録日 2020-03-20 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States. J. Am. Chem. Soc., 142, 2020
5CAM	Crystal Structure of the Cytoplasmic Domain of the Pseudomonas putida Anti-sigma Factor PupR (SeMet) 分子名称: PupR protein 著者 Jensen, J.L, Colbert, C.L. 登録日 2015-06-29 公開日 2015-09-09 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.171 Å) 主引用文献 Mechanistic Implications of the Unique Structural Features and Dimerization of the Cytoplasmic Domain of the Pseudomonas Sigma Regulator, PupR. Biochemistry, 54, 2015
6YPJ	Crystal Structure of CK2alpha with Compound 1 bound 分子名称: 4-[(4-phenyl-1,3-thiazol-2-yl)amino]benzoic acid, ACETATE ION, Casein kinase II subunit alpha 著者 Brear, P, Hyvonen, M. 登録日 2020-04-16 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Proposed Allosteric Inhibitors Bind to the ATP Site of CK2 alpha. J.Med.Chem., 63, 2020
6YPL	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-037 分子名称: (2-methylsulfonylphenyl)methanol, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2020-04-16 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
6YNE	GAPDH purified from the supernatant of HEK293F cells: crystal form 2 of 4. 分子名称: 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Glyceraldehyde-3-phosphate dehydrogenase 著者 Roversi, P, Lia, A. 登録日 2020-04-13 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.853 Å) 主引用文献 Partial catalytic Cys oxidation of human GAPDH to Cys-sulfonic acid. Wellcome Open Res, 5, 2020
6YL3	High resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica 分子名称: NICKEL (II) ION, Urease subunit alpha, Urease subunit beta, ... 著者 Righetto, R.D, Anton, L, Adaixo, R, Jakob, R, Zivanov, J, Mahi, M.A, Ringler, P, Schwede, T, Maier, T, Stahlberg, H. 登録日 2020-04-06 公開日 2020-05-06 最終更新日 2020-10-21 実験手法 ELECTRON MICROSCOPY (1.98 Å) 主引用文献 High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica. Nat Commun, 11, 2020
6YI1	Crystal structure of human glutaminyl cyclase in complex with Glu(gamma-hydrazide)-Phe-Ala 分子名称: 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Kupski, O, Sautner, V, Tittmann, K. 登録日 2020-03-31 公開日 2020-07-01 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Hydrazides Are Potent Transition-State Analogues for Glutaminyl Cyclase Implicated in the Pathogenesis of Alzheimer's Disease. Biochemistry, 59, 2020
6WEU	Crystal structures of human E-NPP 1: bound to adenosine-5'-thio-monophosphate 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Peat, T.S, Dennis, M, Newman, J. 登録日 2020-04-03 公開日 2020-09-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structures of human ENPP1 in apo and bound forms. Acta Crystallogr D Struct Biol, 76, 2020
6WFJ	Crystal structures of human E-NPP 1: apo 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Peat, T.S, Dennis, M, Newman, J. 登録日 2020-04-03 公開日 2020-09-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of human ENPP1 in apo and bound forms. Acta Crystallogr D Struct Biol, 76, 2020
6WUN	Mitochondrial SAM complex - dimer 3 in detergent 分子名称: Bac_surface_Ag domain-containing protein, Sam35 著者 Ni, X, Botos, I, Diederichs, K. 登録日 2020-05-04 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural insight into mitochondrial beta-barrel outer membrane protein biogenesis. Nat Commun, 11, 2020
6WVB	Takifugu rubripes VKOR-like with warfarin 分子名称: S-WARFARIN, Vitamin K epoxide reductase-like protein, termini restrained by green fluorescent protein 著者 Liu, S, Sukumar, N, Li, W. 登録日 2020-05-05 公開日 2020-11-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.872 Å) 主引用文献 Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
6WV7	Human VKOR with Chlorophacinone 分子名称: Chlorophacinone, Vitamin K epoxide reductase, termini restrained by green fluorescent protein 著者 Liu, S, Sukumar, N, Li, W. 登録日 2020-05-05 公開日 2020-11-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.483 Å) 主引用文献 Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science, 371, 2021
6X9B	Structure of proline utilization A with cis-4-hydroxy-D-proline bound in the L-glutamate-gamma-semialdehyde dehydrogenase active site 分子名称: (4R)-4-hydroxy-D-proline, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ... 著者 Tanner, J.J, Campbell, A.C. 登録日 2020-06-02 公開日 2020-12-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Structural analysis of prolines and hydroxyprolines binding to the l-glutamate-gamma-semialdehyde dehydrogenase active site of bifunctional proline utilization A. Arch.Biochem.Biophys., 698, 2020
6XIX	Triuret Hydrolase (TrtA) from Herbaspirillum sp. BH-1 分子名称: BETA-MERCAPTOETHANOL, Cysteine hydrolase 著者 Tassoulas, L.T, Elias, M.H, Wackett, L.P. 登録日 2020-06-22 公開日 2020-11-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of an ultraspecific triuret hydrolase (TrtA) establishes the triuret biodegradation pathway. J.Biol.Chem., 296, 2020
6XJE	Triuret Hydrolase (TrtA) from Herbaspirillum sp. BH-1 C162S bound with triuret 分子名称: 1,2-ETHANEDIOL, Cysteine hydrolase, tricarbonodiimidic diamide 著者 Tassoulas, L.T, Elias, M.H, Wackett, L.P. 登録日 2020-06-23 公開日 2020-11-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Discovery of an ultraspecific triuret hydrolase (TrtA) establishes the triuret biodegradation pathway. J.Biol.Chem., 296, 2020
6X9L	Crystal Structure of Aldehyde Dehydrogenase C (AldC) mutant (C291A) from Pseudomonas syringae in complexed with NAD+ and Octanal 分子名称: Aldehyde dehydrogenase family protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OCTANAL 著者 Lee, S.G, Jez, J.M. 登録日 2020-06-03 公開日 2020-09-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 The plant pathogen enzyme AldC is a long-chain aliphatic aldehyde dehydrogenase. J.Biol.Chem., 295, 2020
3DP5	Crystal structure of Geobacter sulfurreducens OmcF with N-terminal Strep-tag II 分子名称: Cytochrome c family protein, HEME C, SULFATE ION 著者 Lukat, P, Hoffmann, M, Einsle, O. 登録日 2008-07-07 公開日 2008-09-02 最終更新日 2019-10-02 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal packing of the c(6)-type cytochrome OmcF from Geobacter sulfurreducens is mediated by an N-terminal Strep-tag II ACTA CRYSTALLOGR.,SECT.D, 64, 2008
6XE0	Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment) 分子名称: 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Washburn, R, Zuber, P, Sun, M, Hashem, Y, Shen, B, Li, W, Harvey, S, Acosta-Reyes, F.J, Knauer, S.H, Frank, J, Gottesman, M.E. 登録日 2020-06-11 公開日 2020-07-29 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex. Iscience, 23, 2020
6YC8	Crystal structure of KRED1-Pglu enzyme 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ... 著者 Di Pisa, F. 登録日 2020-03-18 公開日 2021-02-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural insights into the desymmetrization of bulky 1,2-dicarbonyls through enzymatic monoreduction. Bioorg.Chem., 108, 2021
4ZVU	Caspase-7 wild-type bound to the caspase-6 cognate tetrapeptide inhibitor Ac-VEID-cho 分子名称: Caspase-7, Tetrapeptide Inhibitor Ac-VEID-CHO 著者 Hardy, J.A, MacPherson, D.J, Hill, M.E. 登録日 2015-05-18 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. Acs Chem.Biol., 11, 2016
6YCH	Crystal structure of GcoA T296A bound to guaiacol 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Aromatic O-demethylase, cytochrome P450 subunit, ... 著者 Mallinson, S.J.B, Hinchen, D.J, Ellis, E.S, DuBois, J.L, Beckham, G.T, McGeehan, J.E. 登録日 2020-03-18 公開日 2021-02-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Engineering a Cytochrome P450 for Demethylation of Lignin-Derived Aromatic Aldehydes. Jacs Au, 1, 2021

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