6YC8

Crystal structure of KRED1-Pglu enzyme

Summary for 6YC8

Entry DOI	10.2210/pdb6yc8/pdb
Descriptor	Ketoreductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETATE ION, ... (8 entities in total)
Functional Keywords	ketoreductase, carbonyl reductase, pichia glucozyma, enantioselective reduction biocatalysis, oxidoreductase
Biological source	Ogataea glucozyma
Total number of polymer chains	1
Total formula weight	31097.94
Authors	Di Pisa, F. (deposition date: 2020-03-18, release date: 2021-02-10, Last modification date: 2024-01-24)
Primary citation	Rabuffetti, M.,Cannazza, P.,Contente, M.L.,Pinto, A.,Romano, D.,Hoyos, P.,Alcantara, A.R.,Eberini, I.,Laurenzi, T.,Gourlay, L.,Di Pisa, F.,Molinari, F. Structural insights into the desymmetrization of bulky 1,2-dicarbonyls through enzymatic monoreduction. Bioorg.Chem., 108:104644-104644, 2021 Cited by PubMed: 33486371 DOI: 10.1016/j.bioorg.2021.104644 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.77 Å)

Structure validation