8SEO
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![BU of 8seo by Molmil](/molmil-images/mine/8seo) | Cryo-EM Structure of RyR1 + ATP-gamma-S | 分子名称: | Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Ryanodine receptor 1, ... | 著者 | Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. | 登録日 | 2023-04-10 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31, 2023
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8SEN
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![BU of 8sen by Molmil](/molmil-images/mine/8sen) | Cryo-EM Structure of RyR1 | 分子名称: | Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION | 著者 | Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. | 登録日 | 2023-04-10 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31, 2023
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8SET
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![BU of 8set by Molmil](/molmil-images/mine/8set) | Cryo-EM Structure of RyR1 + cAMP | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... | 著者 | Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. | 登録日 | 2023-04-10 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31, 2023
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8SEZ
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![BU of 8sez by Molmil](/molmil-images/mine/8sez) | Cryo-EM Structure of RyR1 + Adenine (Local Refinement of TMD) | 分子名称: | ADENINE, Ryanodine receptor 1, ZINC ION | 著者 | Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. | 登録日 | 2023-04-10 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | 主引用文献 | Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31, 2023
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8SEX
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![BU of 8sex by Molmil](/molmil-images/mine/8sex) | Cryo-EM Structure of RyR1 + AMP (Local Refinement of TMD) | 分子名称: | ADENOSINE MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION | 著者 | Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. | 登録日 | 2023-04-10 | 公開日 | 2023-05-24 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31, 2023
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8STH
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![BU of 8sth by Molmil](/molmil-images/mine/8sth) | human STING with diABZI agonist 15 | 分子名称: | 1-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazole-5-carboxamide, Stimulator of interferon genes protein | 著者 | Duvall, J.R, Bukhalid, R.A. | 登録日 | 2023-05-10 | 公開日 | 2023-07-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates. J.Med.Chem., 66, 2023
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8STI
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![BU of 8sti by Molmil](/molmil-images/mine/8sti) | human STING with agonist XMT-1616 | 分子名称: | 3-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-3H-imidazo[4,5-b]pyridine-6-carboxamide, Stimulator of interferon genes protein | 著者 | Duvall, J.R, Bukhalid, R.A. | 登録日 | 2023-05-10 | 公開日 | 2023-07-26 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates. J.Med.Chem., 66, 2023
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7BAH
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![BU of 7bah by Molmil](/molmil-images/mine/7bah) | |
6DC9
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![BU of 6dc9 by Molmil](/molmil-images/mine/6dc9) | |
7BBY
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8ONE
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![BU of 8one by Molmil](/molmil-images/mine/8one) | Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Asp190Ser mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucose | 分子名称: | 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mattoteia, D, De Marco, M, Pinnola, A, Faravelli, S, Scietti, L, Forneris, F. | 登録日 | 2023-04-02 | 公開日 | 2023-07-19 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification of Regulatory Molecular "Hot Spots" for LH/PLOD Collagen Glycosyltransferase Activity. Int J Mol Sci, 24, 2023
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8TCG
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![BU of 8tcg by Molmil](/molmil-images/mine/8tcg) | Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V heavy chain, ... | 著者 | Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. | 登録日 | 2023-06-30 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8. Nat Commun, 14, 2023
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6DC8
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7BMC
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![BU of 7bmc by Molmil](/molmil-images/mine/7bmc) | Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide and stabilizing Fusicoccin A | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... | 著者 | Centorrino, F, Andlovic, B, Ottmann, C. | 登録日 | 2021-01-19 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17, 2022
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7BN2
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7BM9
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![BU of 7bm9 by Molmil](/molmil-images/mine/7bm9) | Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Centorrino, F, Andlovic, B, Ottmann, C. | 登録日 | 2021-01-19 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17, 2022
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7BLZ
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![BU of 7blz by Molmil](/molmil-images/mine/7blz) | Red alga C.merolae Photosystem I | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (3R)-beta,beta-caroten-3-ol, ... | 著者 | Nelson, N, Klaiman, D, Hippler, M. | 登録日 | 2021-01-19 | 公開日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Red alga C.merolae Photosystem I To Be Published
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6D5F
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![BU of 6d5f by Molmil](/molmil-images/mine/6d5f) | Cryo-EM reconstruction of membrane-enveloped filamentous virus SFV1 (Sulfolobus filamentous virus 1) | 分子名称: | DNA (336-MER), Fimbrial protein | 著者 | Wang, F, Osinski, T, Liu, Y, Krupovic, M, Prangishvili, D, Egelman, E.H. | 登録日 | 2018-04-19 | 公開日 | 2018-08-29 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural conservation in a membrane-enveloped filamentous virus infecting a hyperthermophilic acidophile. Nat Commun, 9, 2018
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6DN7
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6D9W
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![BU of 6d9w by Molmil](/molmil-images/mine/6d9w) | Crystal structure of Deinococcus radiodurans MntH, an Nramp-family transition metal transporter, in the inward-open apo state | 分子名称: | Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain, ... | 著者 | Gaudet, R, Bane, L.B, Weihofen, W.A, Singharoy, A, Zimanyi, C.M, Bozzi, A.T. | 登録日 | 2018-04-30 | 公開日 | 2019-02-13 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (3.941 Å) | 主引用文献 | Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter. Elife, 8, 2019
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7C1M
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![BU of 7c1m by Molmil](/molmil-images/mine/7c1m) | Complex structure of tyrosinated alpha-tubulin carboxy-terminal peptide and A1aY1 binder | 分子名称: | Carboxy-terminal peptide from tyrosinated alpha-tubulin, Nanobody binder from SSO7d library | 著者 | Kesarwani, S, Reddy, P.P, Sirajuddin, M, Das, R. | 登録日 | 2020-05-05 | 公開日 | 2020-09-02 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Genetically encoded live-cell sensor for tyrosinated microtubules. J.Cell Biol., 219, 2020
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7BQE
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![BU of 7bqe by Molmil](/molmil-images/mine/7bqe) | Solution NMR structure of NF3; de novo designed protein with a novel fold | 分子名称: | NF3 | 著者 | Kobayashi, N, Sugiki, T, Fujiwara, T, Minami, S, Koga, R, Chikenji, G, Koga, N. | 登録日 | 2020-03-24 | 公開日 | 2021-03-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Exploration of novel alpha-beta-protein folds through de novo design Nat.Struct.Mol.Biol., 2023
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7BZH
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7BQQ
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![BU of 7bqq by Molmil](/molmil-images/mine/7bqq) | Solution NMR structure of fold-Z Gogy; de novo designed protein with an asymmetric all-alpha topology | 分子名称: | Gogy | 著者 | Kobayashi, N, Sugiki, T, Fujiwara, T, Sakuma, K, Kosugi, T, Koga, R, Koga, N. | 登録日 | 2020-03-25 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Design of complicated all-alpha protein structures Nat.Struct.Mol.Biol., 2024
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7BQM
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![BU of 7bqm by Molmil](/molmil-images/mine/7bqm) | Solution NMR structure of fold-0 Chantal; de novo designed protein with an asymmetric all-alpha topology | 分子名称: | Chantal | 著者 | Kobayashi, N, Sugiki, T, Fujiwara, T, Sakuma, K, Kosugi, T, Koga, R, Koga, N. | 登録日 | 2020-03-25 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Design of complicated all-alpha protein structures Nat.Struct.Mol.Biol., 2024
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