PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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8SEO	Cryo-EM Structure of RyR1 + ATP-gamma-S 分子名称: Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Ryanodine receptor 1, ... 著者 Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. 登録日 2023-04-10 公開日 2023-05-24 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.92 Å) 主引用文献 Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31, 2023
8SEN	Cryo-EM Structure of RyR1 分子名称: Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION 著者 Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. 登録日 2023-04-10 公開日 2023-05-24 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.49 Å) 主引用文献 Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31, 2023
8SET	Cryo-EM Structure of RyR1 + cAMP 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... 著者 Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. 登録日 2023-04-10 公開日 2023-05-24 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31, 2023
8SEZ	Cryo-EM Structure of RyR1 + Adenine (Local Refinement of TMD) 分子名称: ADENINE, Ryanodine receptor 1, ZINC ION 著者 Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. 登録日 2023-04-10 公開日 2023-05-24 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31, 2023
8SEX	Cryo-EM Structure of RyR1 + AMP (Local Refinement of TMD) 分子名称: ADENOSINE MONOPHOSPHATE, Ryanodine receptor 1, ZINC ION 著者 Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S. 登録日 2023-04-10 公開日 2023-05-24 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.84 Å) 主引用文献 Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives. Structure, 31, 2023
8STH	human STING with diABZI agonist 15 分子名称: 1-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazole-5-carboxamide, Stimulator of interferon genes protein 著者 Duvall, J.R, Bukhalid, R.A. 登録日 2023-05-10 公開日 2023-07-26 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates. J.Med.Chem., 66, 2023
8STI	human STING with agonist XMT-1616 分子名称: 3-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-3H-imidazo[4,5-b]pyridine-6-carboxamide, Stimulator of interferon genes protein 著者 Duvall, J.R, Bukhalid, R.A. 登録日 2023-05-10 公開日 2023-07-26 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates. J.Med.Chem., 66, 2023
7BAH	Structure of RIG-I CTD bound to OH-RNA 分子名称: Antiviral innate immune response receptor RIG-I, RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3'), ZINC ION 著者 Anand, K, Hagelueken, G, Fusshoeller, D, Geyer, M. 登録日 2020-12-15 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA To Be Published
6DC9	Fab/epitope complex of human chimeric monoclonal antibody h4E6 targeting a phosphorylated tau epitope. 分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ... 著者 Chukwu, J.E, Kong, X.-P. 登録日 2018-05-04 公開日 2019-03-20 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (2.999 Å) 主引用文献 Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein. MAbs, 11, 2019
7BBY	Crystal structure of aldo-keto reductase with C-terminal His tag from Agrobacterium tumefaciens 分子名称: Aryl-alcohol dehydrogenase, PHOSPHATE ION 著者 Snow, A, Sharma, M, Davies, G.J. 登録日 2020-12-18 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria. Proc.Natl.Acad.Sci.USA, 119, 2022
8ONE	Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Asp190Ser mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucose 分子名称: 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Mattoteia, D, De Marco, M, Pinnola, A, Faravelli, S, Scietti, L, Forneris, F. 登録日 2023-04-02 公開日 2023-07-19 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Identification of Regulatory Molecular "Hot Spots" for LH/PLOD Collagen Glycosyltransferase Activity. Int J Mol Sci, 24, 2023
8TCG	Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V heavy chain, ... 著者 Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. 登録日 2023-06-30 公開日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8. Nat Commun, 14, 2023
6DC8	Fab/epitope complex of mouse monoclonal antibody 8B2 targeting a non-phosphorylated tau epitope. 分子名称: GLYCEROL, IgG heavy chain, IgG light chain, ... 著者 Chukwu, J.E, Kong, X.-P. 登録日 2018-05-04 公開日 2019-03-20 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Structural characterization of monoclonal antibodies targeting C-terminal Ser404region of phosphorylated tau protein. MAbs, 11, 2019
7BMC	Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide and stabilizing Fusicoccin A 分子名称: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2021-01-19 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17, 2022
7BN2	Clathrin heavy chain N-terminal domain bound to Non structured protein 3 from Eastern Equine Encephalitis Virus 分子名称: Clathrin heavy chain 1, Non structured protein 3 from Eastern Equine Encephalitis Virus, PHOSPHATE ION, ... 著者 Badgujar, D.C, Dobritzsch, D. 登録日 2021-01-21 公開日 2022-03-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.965 Å) 主引用文献 Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs Nat Commun, 14, 2023
7BM9	Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2021-01-19 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17, 2022
7BLZ	Red alga C.merolae Photosystem I 分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (3R)-beta,beta-caroten-3-ol, ... 著者 Nelson, N, Klaiman, D, Hippler, M. 登録日 2021-01-19 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Red alga C.merolae Photosystem I To Be Published
6D5F	Cryo-EM reconstruction of membrane-enveloped filamentous virus SFV1 (Sulfolobus filamentous virus 1) 分子名称: DNA (336-MER), Fimbrial protein 著者 Wang, F, Osinski, T, Liu, Y, Krupovic, M, Prangishvili, D, Egelman, E.H. 登録日 2018-04-19 公開日 2018-08-29 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural conservation in a membrane-enveloped filamentous virus infecting a hyperthermophilic acidophile. Nat Commun, 9, 2018
6DN7	SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) Cyclic peptide inhibitor 分子名称: CHLORIDE ION, SPRY domain-containing SOCS box protein 4, WDINNN(BAL) Cyclic peptide inhibitor 著者 Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S. 登録日 2018-06-06 公開日 2019-04-17 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. ACS Chem. Biol., 13, 2018
6D9W	Crystal structure of Deinococcus radiodurans MntH, an Nramp-family transition metal transporter, in the inward-open apo state 分子名称: Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain, ... 著者 Gaudet, R, Bane, L.B, Weihofen, W.A, Singharoy, A, Zimanyi, C.M, Bozzi, A.T. 登録日 2018-04-30 公開日 2019-02-13 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (3.941 Å) 主引用文献 Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter. Elife, 8, 2019
7C1M	Complex structure of tyrosinated alpha-tubulin carboxy-terminal peptide and A1aY1 binder 分子名称: Carboxy-terminal peptide from tyrosinated alpha-tubulin, Nanobody binder from SSO7d library 著者 Kesarwani, S, Reddy, P.P, Sirajuddin, M, Das, R. 登録日 2020-05-05 公開日 2020-09-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Genetically encoded live-cell sensor for tyrosinated microtubules. J.Cell Biol., 219, 2020
7BQE	Solution NMR structure of NF3; de novo designed protein with a novel fold 分子名称: NF3 著者 Kobayashi, N, Sugiki, T, Fujiwara, T, Minami, S, Koga, R, Chikenji, G, Koga, N. 登録日 2020-03-24 公開日 2021-03-24 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Exploration of novel alpha-beta-protein folds through de novo design Nat.Struct.Mol.Biol., 2023
7BZH	Solution structure of a DNA binding protein from Sulfolobus islandicus 分子名称: Sul7s 著者 Zhang, Z, Liu, X. 登録日 2020-04-28 公開日 2021-04-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 A Novel Family of Winged-Helix Single-Stranded DNA-Binding Proteins from Archaea. Int J Mol Sci, 23, 2022
7BQQ	Solution NMR structure of fold-Z Gogy; de novo designed protein with an asymmetric all-alpha topology 分子名称: Gogy 著者 Kobayashi, N, Sugiki, T, Fujiwara, T, Sakuma, K, Kosugi, T, Koga, R, Koga, N. 登録日 2020-03-25 公開日 2021-04-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Design of complicated all-alpha protein structures Nat.Struct.Mol.Biol., 2024
7BQM	Solution NMR structure of fold-0 Chantal; de novo designed protein with an asymmetric all-alpha topology 分子名称: Chantal 著者 Kobayashi, N, Sugiki, T, Fujiwara, T, Sakuma, K, Kosugi, T, Koga, R, Koga, N. 登録日 2020-03-25 公開日 2021-04-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Design of complicated all-alpha protein structures Nat.Struct.Mol.Biol., 2024

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