8SET

Cryo-EM Structure of RyR1 + cAMP

This is a non-PDB format compatible entry.

Summary for 8SET

• Entry DOI: 10.2210/pdb8set/pdb
• EMDB information: 40422 40423 40424 40425 40426 40427 40428 40429 40430 40431 40432 40433 40434 40435
• Descriptor: Ryanodine receptor 1, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... (4 entities in total)
• Functional Keywords: calcium ion channel, skeletal muscle, nucleotide, homotetramer, transport protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 2425393.01

Authors

Cholak, S.,Saville, J.W.,Zhu, X.,Berezuk, A.M.,Tuttle, K.S.,Haji-Ghassemi, O.,Van Petegem, F.,Subramaniam, S. (deposition date: 2023-04-10, release date: 2023-05-24, Last modification date: 2023-07-19)

• Primary citation: Cholak, S.,Saville, J.W.,Zhu, X.,Berezuk, A.M.,Tuttle, K.S.,Haji-Ghassemi, O.,Alvarado, F.J.,Van Petegem, F.,Subramaniam, S.; Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.; Structure, 31:790-800.e4, 2023; PubMed: 37192614; DOI: 10.1016/j.str.2023.04.009

Experimental method

ELECTRON MICROSCOPY (3.42 Å)