8ONE

Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Asp190Ser mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucose

Summary for 8ONE

Entry DOI	10.2210/pdb8one/pdb
Descriptor	Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-OXOGLUTARIC ACID, ... (9 entities in total)
Functional Keywords	collagen biosynthesis; extracellular matrix; post-translational modifications; collagen glycosylations; glycosyltransferase; lysyl hydroxylase, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	1
Total formula weight	84614.37
Authors	Mattoteia, D.,De Marco, M.,Pinnola, A.,Faravelli, S.,Scietti, L.,Forneris, F. (deposition date: 2023-04-02, release date: 2023-07-19, Last modification date: 2023-08-09)
Primary citation	Mattoteia, D.,Chiapparino, A.,Fumagalli, M.,De Marco, M.,De Giorgi, F.,Negro, L.,Pinnola, A.,Faravelli, S.,Roscioli, T.,Scietti, L.,Forneris, F. Identification of Regulatory Molecular "Hot Spots" for LH/PLOD Collagen Glycosyltransferase Activity. Int J Mol Sci, 24:-, 2023 Cited by PubMed: 37446392 DOI: 10.3390/ijms241311213 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation