PDB: 97922 件ウェブページステータス検索Chemie searchBIRD

---

5TYA	Identification of a New Zinc Binding Chemotype by Fragment Screening 分子名称: (5R)-5-phenyl-1,3-thiazolidine-2,4-dione, Carbonic anhydrase 2, ZINC ION 著者 Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. 登録日 2016-11-18 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
6FKZ	Crystal structure of zebrafish Sirtuin 5 in complex with 3-(phenylthio)succinyl-CPS1 peptide 分子名称: 3(R)-(phenylthio)succinyl-CPS1 peptide, 3(S)-(phenylthio)succinyl-CPS1 peptide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Pannek, M, Steegborn, C. 登録日 2018-01-25 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Potent and Selective Inhibitors of Human Sirtuin 5. J. Med. Chem., 61, 2018
7S9E	Cryo-EM Structure of dolphin Prestin: Inhibited II (Sulfate +Salicylate) state 分子名称: 2-HYDROXYBENZOIC ACID, Prestin 著者 Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. 登録日 2021-09-20 公開日 2021-11-03 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 The conformational cycle of prestin underlies outer-hair cell electromotility. Nature, 600, 2021
7S8X	Cryo-EM Structure of dolphin Prestin: Sensor Up (compact) state 分子名称: Prestin 著者 Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. 登録日 2021-09-20 公開日 2021-11-03 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The conformational cycle of prestin underlies outer-hair cell electromotility. Nature, 600, 2021
7S9C	Cryo-EM Structure of dolphin Prestin: Sensor Down II (Expanded II) state 分子名称: Prestin 著者 Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. 登録日 2021-09-20 公開日 2021-11-03 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 The conformational cycle of prestin underlies outer-hair cell electromotility. Nature, 600, 2021
7S9D	Cryo-EM Structure of dolphin Prestin: Intermediate state 分子名称: Prestin 著者 Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. 登録日 2021-09-20 公開日 2021-11-03 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 The conformational cycle of prestin underlies outer-hair cell electromotility. Nature, 600, 2021
7O3B	Crystal structure of the TTBK2-CEP164 complex bound to a camelid nanobody 分子名称: Nanobody 36Z, Tau-tubulin kinase 2,Centrosomal protein of 164 kDa 著者 e Silva, I.R, van Breugel, M. 登録日 2021-04-01 公開日 2021-09-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies. Structure, 30, 2022
7S9A	Cryo-EM Structure of dolphin Prestin: Inhibited I (Chloride + Salicylate) 分子名称: 2-HYDROXYBENZOIC ACID, Prestin 著者 Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. 登録日 2021-09-20 公開日 2021-11-03 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 The conformational cycle of prestin underlies outer-hair cell electromotility. Nature, 600, 2021
7O0S	Crystal structure of the N-terminal domain of CEP164(1-109) bound to camelid nanobody 36Z 分子名称: Centrosomal protein of 164 kDa, Nanobody 36Z 著者 e Silva, I.R, van Breugel, M. 登録日 2021-03-26 公開日 2021-09-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies. Structure, 30, 2022
7S9B	Cryo-EM Structure of dolphin Prestin: Sensor Down I (Expanded) state 分子名称: Prestin 著者 Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. 登録日 2021-09-20 公開日 2021-11-03 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 The conformational cycle of prestin underlies outer-hair cell electromotility. Nature, 600, 2021
4HS2	Crystal Structure of the Human SPOP C-terminal Domain 分子名称: Speckle-type POZ protein 著者 Van Geersdaele, L.K, Stead, M.A, Carr, S.B, Wright, S.C. 登録日 2012-10-29 公開日 2013-09-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP. Acta Crystallogr.,Sect.D, 69, 2013
6CB1	Yeast nucleolar pre-60S ribosomal subunit (state 3) 分子名称: 35S pre-ribosomal RNA miscRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... 著者 Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. 登録日 2018-02-01 公開日 2018-03-14 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature, 556, 2018
2YJW	Tricyclic series of Hsp90 inhibitors 分子名称: 4-(5-METHYL-4-PHENYLISOXAZOL-3-YL)BENZENE-1,3-DIOL, HEAT SHOCK PROTEIN HSP 90-ALPHA 著者 Dupuy, A, Vallee, F. 登録日 2011-05-24 公開日 2011-10-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-C]Pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone. J.Med.Chem., 54, 2011
5U0F	Identification of a New Zinc Binding Chemotype by Fragment Screening 分子名称: (5R)-5-[(2,4-dimethoxyphenyl)methyl]-2-sulfanylidene-1,3-thiazolidin-4-one, Carbonic anhydrase 2, ZINC ION 著者 Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. 登録日 2016-11-23 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
1NNU	Crystal Structure Analysis of Plasmodium falciparum enoyl-acyl-carrier-protein reductase with Triclosan Analog 分子名称: 6-(4-CHLORO-2-HYDROXY-PHENOXY)-NAPHTHALEN-2-OL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, enoyl-acyl carrier reductase 著者 Perozzo, R, Kuo, M, Sidhu, A.S, Valiyaveettil, J.T, Bittman, R, Jacobs Jr, W.R, Fidock, D.A, Sacchettini, J.C. 登録日 2003-01-14 公開日 2003-02-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Elucidation of the Specificity of the Antibacterial Agent Triclosan for Malarial Enoyl Acyl Carrier Protein Reductase J.Biol.Chem., 277, 2002
5TY9	Identification of a New Zinc Binding Chemotype by Fragment Screening 分子名称: (5R)-5-(2,4-dimethoxyphenyl)-1,3-oxazolidine-2,4-dione, Carbonic anhydrase 2, ZINC ION 著者 Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. 登録日 2016-11-18 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
4EU1	Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Mitochondrial aspartate aminotransferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-04-25 公開日 2012-05-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr F Struct Biol Commun, 71, 2015
2BGU	CRYSTAL STRUCTURE OF THE DNA MODIFYING ENZYME BETA-GLUCOSYLTRANSFERASE IN THE PRESENCE AND ABSENCE OF THE SUBSTRATE URIDINE DIPHOSPHOGLUCOSE 分子名称: BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE 著者 Vrielink, A, Rueger, W, Driessen, H.P.C, Freemont, P.S. 登録日 1994-06-09 公開日 1995-12-09 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose. EMBO J., 13, 1994
3OJ2	Crystal structure of FGF1 complexed with the ectodomain of FGFR2b harboring the A172F Pfeiffer syndrome mutation 分子名称: Fibroblast growth factor receptor 2, Heparin-binding growth factor 1, SULFATE ION 著者 Beenken, A, Mohammadi, M. 登録日 2010-08-20 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1. J.Biol.Chem., 287, 2012
1OAA	MOUSE SEPIAPTERIN REDUCTASE COMPLEXED WITH NADP AND OXALOACETATE 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OXALOACETATE ION, SEPIAPTERIN REDUCTASE, ... 著者 Auerbach, G, Herrmann, A, Bacher, A, Huber, R. 登録日 1997-08-25 公開日 1999-02-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters. EMBO J., 16, 1997
7RXH	afTMEM16 in C18 lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+, monomer with extra lipids 分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, afTMEM16 lipid scramblase 著者 Falzone, M.E, Accardi, A. 登録日 2021-08-23 公開日 2022-05-18 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 TMEM16 scramblases thin the membrane to enable lipid scrambling. Nat Commun, 13, 2022
2BTC	BOVINE TRYPSIN IN COMPLEX WITH SQUASH SEED INHIBITOR (CUCURBITA PEPO TRYPSIN INHIBITOR II) 分子名称: CALCIUM ION, PROTEIN (TRYPSIN INHIBITOR), PROTEIN (TRYPSIN) 著者 Helland, R, Berglund, G.I, Otlewski, J, Apostoluk, W, Andersen, O.A, Willassen, N.P, Smalas, A.O. 登録日 1998-12-11 公開日 2000-01-19 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-resolution structures of three new trypsin-squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes. Acta Crystallogr.,Sect.D, 55, 1999
1NT9	Complete 12-subunit RNA polymerase II 分子名称: DNA-DIRECTED RNA POLYMERASE II 13.6 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT, ... 著者 Armache, K.-J, Kettenberger, H, Cramer, P. 登録日 2003-01-29 公開日 2003-04-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Architecture of initiation-competent 12-subunit RNA polymerase II Proc.Natl.Acad.Sci.USA, 100, 2003
8CNK	Cryo-EM structure of retinal-free proteoopsin bound to decanoate 分子名称: DECANOIC ACID, Green-light absorbing proteorhodopsin 著者 Hirschi, S, Lemmin, T, Fotiadis, D. 登録日 2023-02-23 公開日 2024-07-03 最終更新日 2024-09-04 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structural insights into the mechanism and dynamics of proteorhodopsin biogenesis and retinal scavenging. Nat Commun, 15, 2024
6CHA	STRUCTURE OF A TETRAHEDRAL TRANSITION STATE COMPLEX OF ALPHA-*CHYMOTRYPSIN AT 1.8-*ANGSTROMS RESOLUTION 分子名称: ALPHA-CHYMOTRYPSIN A, PHENYLETHANE BORONIC ACID 著者 Tulinsky, A, Blevins, R.A. 登録日 1987-02-06 公開日 1987-04-16 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of a tetrahedral transition state complex of alpha-chymotrypsin dimer at 1.8-A resolution. J.Biol.Chem., 262, 1987

<666667668669670671672673674675676677678679680681>