7Z9B
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![BU of 7z9b by Molmil](/molmil-images/mine/7z9b) | Sam68 | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, IODIDE ION, ... | 著者 | Nadal, M, Fuentes-Prior, P. | 登録日 | 2022-03-20 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.333 Å) | 主引用文献 | Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts. Protein Sci., 32, 2023
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7Z8A
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![BU of 7z8a by Molmil](/molmil-images/mine/7z8a) | Sam68 | 分子名称: | 1,2-ETHANEDIOL, KHDR1 protein, LITHIUM ION, ... | 著者 | Nadal, M, Fuentes-Prior, P. | 登録日 | 2022-03-16 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts. Protein Sci., 32, 2023
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7ZAF
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![BU of 7zaf by Molmil](/molmil-images/mine/7zaf) | Sam68 | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Nadal, M, Puestes-Prior, P. | 登録日 | 2022-03-22 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts. Protein Sci., 32, 2023
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7ZAC
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![BU of 7zac by Molmil](/molmil-images/mine/7zac) | Sam68 | 分子名称: | 1,2-ETHANEDIOL, KHDR1 protein, NITRATE ION | 著者 | Nadal, M, Fuentes-Prior, P. | 登録日 | 2022-03-22 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts. Protein Sci., 32, 2023
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7YPZ
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![BU of 7ypz by Molmil](/molmil-images/mine/7ypz) | Zafirlukast in complex with CRM1-Ran-RanBP1 | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | 著者 | Sun, Q, Lei, Y. | 登録日 | 2022-08-05 | 公開日 | 2023-08-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Searching for Novel Noncovalent Nuclear Export Inhibitors through a Drug Repurposing Approach. J.Med.Chem., 66, 2023
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7ZAU
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![BU of 7zau by Molmil](/molmil-images/mine/7zau) | Fascin-1 in complex with Nb 3E11 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fascin, ... | 著者 | Burgess, S.G, Bayliss, R. | 登録日 | 2022-03-22 | 公開日 | 2023-09-27 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A nanobody inhibitor of Fascin-1 actin-bundling activity and filopodia formation. Open Biology, 14, 2024
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7ZVX
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![BU of 7zvx by Molmil](/molmil-images/mine/7zvx) | Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 2.4 A resolution | 分子名称: | 1,2-ETHANEDIOL, 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, ... | 著者 | Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M. | 登録日 | 2022-05-17 | 公開日 | 2022-09-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding. Nucleic Acids Res., 51, 2023
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7ZVN
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![BU of 7zvn by Molmil](/molmil-images/mine/7zvn) | Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 1.87 A resolution | 分子名称: | 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, CALCIUM ION, ... | 著者 | Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M. | 登録日 | 2022-05-16 | 公開日 | 2022-09-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding. Nucleic Acids Res., 51, 2023
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1HZW
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![BU of 1hzw by Molmil](/molmil-images/mine/1hzw) | CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE | 分子名称: | PHOSPHATE ION, THYMIDYLATE SYNTHASE | 著者 | Almog, R, Waddling, C.A, Maley, F, Maley, G.F, Van Roey, P. | 登録日 | 2001-01-26 | 公開日 | 2001-05-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP. Protein Sci., 10, 2001
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1I00
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![BU of 1i00 by Molmil](/molmil-images/mine/1i00) | CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE, TERNARY COMPLEX WITH DUMP AND TOMUDEX | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | 著者 | Almog, R.A, Waddling, C.A, Maley, F, Maley, G.F, Van Roey, P. | 登録日 | 2001-01-27 | 公開日 | 2001-05-09 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP. Protein Sci., 10, 2001
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1EXX
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![BU of 1exx by Molmil](/molmil-images/mine/1exx) | ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE INACTIVE S-ENANTIOMER BMS270395. | 分子名称: | 3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID, DODECYL-ALPHA-D-MALTOSIDE, RETINOIC ACID RECEPTOR GAMMA-2 | 著者 | Klaholz, B.P, Mitschler, A, Belema, M, Zusi, C, Moras, D, Structural Proteomics in Europe (SPINE) | 登録日 | 2000-05-05 | 公開日 | 2000-06-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. Proc.Natl.Acad.Sci.USA, 97, 2000
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3MB4
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![BU of 3mb4 by Molmil](/molmil-images/mine/3mb4) | Crystal Structure of the fifth Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) with NMP | 分子名称: | 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, CHLORIDE ION, ... | 著者 | Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2010-03-25 | 公開日 | 2010-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
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1EX5
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![BU of 1ex5 by Molmil](/molmil-images/mine/1ex5) | |
1EWD
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![BU of 1ewd by Molmil](/molmil-images/mine/1ewd) | |
1J4E
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![BU of 1j4e by Molmil](/molmil-images/mine/1j4e) | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE COVALENTLY BOUND TO THE SUBSTRATE DIHYDROXYACETONE PHOSPHATE | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, FRUCTOSE-BISPHOSPHATE ALDOLASE A | 著者 | Choi, K.H, Shi, J, Hopkins, C.E, Tolan, D.R, Allen, K.N. | 登録日 | 2001-09-19 | 公開日 | 2002-02-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Snapshots of catalysis: the structure of fructose-1,6-(bis)phosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate. Biochemistry, 40, 2001
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3NQJ
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![BU of 3nqj by Molmil](/molmil-images/mine/3nqj) | |
3O2T
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![BU of 3o2t by Molmil](/molmil-images/mine/3o2t) | |
1F3C
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![BU of 1f3c by Molmil](/molmil-images/mine/1f3c) | |
3NNC
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![BU of 3nnc by Molmil](/molmil-images/mine/3nnc) | Crystal Structure of CUGBP1 RRM1/2-RNA Complex | 分子名称: | CUGBP Elav-like family member 1, RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*UP*GP*UP*GP*UP*G)-3') | 著者 | Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J. | 登録日 | 2010-06-23 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2005 Å) | 主引用文献 | Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1. Structure, 18, 2010
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3O50
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![BU of 3o50 by Molmil](/molmil-images/mine/3o50) | Crystal structure of benzamide 9 bound to AuroraA | 分子名称: | N-{3-methyl-4-[(3-pyrimidin-4-ylpyridin-2-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide, cDNA FLJ58295, highly similar to Serine/threonine-protein kinase 6 | 著者 | Huang, X. | 登録日 | 2010-07-27 | 公開日 | 2010-08-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor. J.Med.Chem., 53, 2010
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3NRM
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![BU of 3nrm by Molmil](/molmil-images/mine/3nrm) | Imidazo[1,2-a]pyrazine-based Aurora Kinase Inhibitors | 分子名称: | N-(3-methylisothiazol-5-yl)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine, Serine/threonine-protein kinase 6 | 著者 | Hruza, A. | 登録日 | 2010-06-30 | 公開日 | 2010-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Discovery of imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
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3NNA
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![BU of 3nna by Molmil](/molmil-images/mine/3nna) | Crystal Structure of CUGBP1 RRM1/2-RNA Complex | 分子名称: | CUGBP Elav-like family member 1, RNA (5'-R(*GP*UP*UP*GP*UP*UP*UP*UP*GP*UP*UP*U)-3') | 著者 | Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J. | 登録日 | 2010-06-23 | 公開日 | 2010-10-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1. Structure, 18, 2010
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1F68
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1F95
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![BU of 1f95 by Molmil](/molmil-images/mine/1f95) | SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND BIM PEPTIDE COMPLEX | 分子名称: | BCL2-LIKE 11 (APOPTOSIS FACILITATOR), DYNEIN | 著者 | Fan, J.-S, Zhang, Q, Tochio, H, Li, M, Zhang, M. | 登録日 | 2000-07-07 | 公開日 | 2001-02-28 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain. J.Mol.Biol., 306, 2001
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1FCY
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![BU of 1fcy by Molmil](/molmil-images/mine/1fcy) | ISOTYPE SELECTIVITY OF THE HUMAN RETINOIC ACID NUCLEAR RECEPTOR HRAR: THE COMPLEX WITH THE RARBETA/GAMMA-SELECTIVE RETINOID CD564 | 分子名称: | 6-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTALENE-2-CARBONYL)-NAPHTALENE-2-CARBOXYLIC ACID, DODECYL-ALPHA-D-MALTOSIDE, RETINOIC ACID RECEPTOR GAMMA-1 | 著者 | Klaholz, B.P, Mitschler, A, Moras, D, Structural Proteomics in Europe (SPINE) | 登録日 | 2000-07-19 | 公開日 | 2000-09-11 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structural basis for isotype selectivity of the human retinoic acid nuclear receptor. J.Mol.Biol., 302, 2000
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