3MB4
Crystal Structure of the fifth Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) with NMP
Summary for 3MB4
Entry DOI | 10.2210/pdb3mb4/pdb |
Related | 3MB3 |
Descriptor | Protein polybromo-1, 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, ... (5 entities in total) |
Functional Keywords | pb1, polybromo 1 isoform 1, baf180, polybromo-1d, pbrm1, brg1-associated factor 180, structural genomics consortium, sgc, bromodomain, chromatin regulator, dna-binding, nucleus, phosphoprotein, transcription, transcription regulation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q86U86 |
Total number of polymer chains | 2 |
Total formula weight | 29946.41 |
Authors | Filippakopoulos, P.,Picaud, S.,Keates, T.,Ugochukwu, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-03-25, release date: 2010-04-14, Last modification date: 2023-09-06) |
Primary citation | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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