3MB3

Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP)

Summary for 3MB3

Entry DOI	10.2210/pdb3mb3/pdb
Related	3MB4
Descriptor	PH-interacting protein, 1-methylpyrrolidin-2-one (3 entities in total)
Functional Keywords	phip, pleckstrin homology domain interacting protein, dcaf14, ndrp, ddb1 and cul4 associated factor 14, sgc, structural genomics consortium, bromodomain, phosphoprotein, wd repeat, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Nucleus (By similarity): Q8WWQ0
Total number of polymer chains	1
Total formula weight	16230.39
Authors	Filippakopoulos, P.,Picaud, S.,Keates, T.,Ugochukwu, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2010-03-25, release date: 2010-04-14, Last modification date: 2023-09-06)
Primary citation	Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331 DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation