Crystal Structure of CUGBP1 RRM1/2-RNA Complex

Summary for 3NNA

Related3NMR 3NNC 3NNH
DescriptorCUGBP Elav-like family member 1, RNA (5'-R(*GP*UP*UP*GP*UP*UP*UP*UP*GP*UP*UP*U)-3') (3 entities in total)
Functional Keywordsrrm, rna binding, rna, rna binding protein-rna complex, rna binding protein/rna
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q92879
Total number of polymer chains2
Total molecular weight23972.93
Teplova, M.,Song, J.,Gaw, H.,Teplov, A.,Patel, D.J. (deposition date: 2010-06-23, release date: 2010-10-27, Last modification date: 2014-10-08)
Primary citation
Teplova, M.,Song, J.,Gaw, H.Y.,Teplov, A.,Patel, D.J.
Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1.
Structure, 18:1364-1377, 2010
PubMed: 20947024 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2010.06.018
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.2481904.7%8.8%0.46MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3nna
no rotation
Molmil generated image of 3nna
rotated about x axis by 90°
Molmil generated image of 3nna
rotated about y axis by 90°