5EZU
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![BU of 5ezu by Molmil](/molmil-images/mine/5ezu) | Crystal structure of the N-terminal domain of vaccinia virus immunomodulator A46 in complex with myristic acid. | 分子名称: | MYRISTIC ACID, Protein A46 | 著者 | Fedosyuk, S, Bezerra, G.A, Sammito, M, Uson, I, Skern, T. | 登録日 | 2015-11-26 | 公開日 | 2016-11-30 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins. PLoS Pathog., 12, 2016
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4XYM
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7VEG
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![BU of 7veg by Molmil](/molmil-images/mine/7veg) | Understanding NH-pi interaction between Gln and Phe | 分子名称: | (2~{S},4~{R})-4-oxidanylpyrrolidine-2-carboxamide, ACETYLAMINO-ACETIC ACID, peptide | 著者 | Fan, S, Xu, F. | 登録日 | 2021-09-08 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.385 Å) | 主引用文献 | Structural Achievability of an NH-pi Interaction between Gln and Phe in a Crystal Structure of a Collagen-like Peptide. Biomolecules, 12, 2022
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5EXX
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![BU of 5exx by Molmil](/molmil-images/mine/5exx) | AAA+ ATPase FleQ from Pseudomonas aeruginosa bound to c-di-GMP | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), SULFATE ION, Transcriptional regulator FleQ | 著者 | Navarro, M.V.A.S, Sondermann, H, Krasteva, P.V. | 登録日 | 2015-11-24 | 公開日 | 2016-02-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.311 Å) | 主引用文献 | Mechanistic insights into c-di-GMP-dependent control of the biofilm regulator FleQ from Pseudomonas aeruginosa. Proc.Natl.Acad.Sci.USA, 113, 2016
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4XFY
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6SLU
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![BU of 6slu by Molmil](/molmil-images/mine/6slu) | Structure of the native full-length HIV-1 capsid protein A92E in helical assembly (-13,11) | 分子名称: | Gag protein | 著者 | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | 登録日 | 2019-08-20 | 公開日 | 2020-09-09 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27, 2020
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4KWW
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![BU of 4kww by Molmil](/molmil-images/mine/4kww) | The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid | 分子名称: | Nicotinate-nucleotide pyrophosphorylase [carboxylating], PHTHALIC ACID | 著者 | Malik, S.S, Dimeka, P.N, Ncube, Z, Toth, E.A. | 登録日 | 2013-05-24 | 公開日 | 2013-10-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid. Proteins, 82, 2014
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6SO1
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![BU of 6so1 by Molmil](/molmil-images/mine/6so1) | Fragment N13569a in complex with MAP kinase p38-alpha | 分子名称: | 1-(1,3-benzodioxol-5-yl)-~{N}-[[(2~{R})-oxolan-2-yl]methyl]methanamine, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Nichols, C.E, De Nicola, G.F. | 登録日 | 2019-08-28 | 公開日 | 2019-10-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
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6SOI
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![BU of 6soi by Molmil](/molmil-images/mine/6soi) | Fragment N13788a in complex with MAP kinase p38-alpha | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Nichols, C.E, De Nicola, G.F. | 登録日 | 2019-08-29 | 公開日 | 2019-10-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
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6SOT
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![BU of 6sot by Molmil](/molmil-images/mine/6sot) | Fragment N11290a in complex with MAP kinase p38-alpha | 分子名称: | 1,2-ETHANEDIOL, 1-(4-methylphenyl)pyrrolidine-2,5-dione, CHLORIDE ION, ... | 著者 | Nichols, C.E, De Nicola, G.F. | 登録日 | 2019-08-29 | 公開日 | 2019-10-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
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7KOD
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![BU of 7kod by Molmil](/molmil-images/mine/7kod) | Cryo-EM structure of heavy chain mouse apoferritin | 分子名称: | Ferritin heavy chain | 著者 | Sun, M, Azumaya, C, Tse, E, Frost, A, Southworth, D, Verba, K.A, Cheng, Y, Agard, D.A. | 登録日 | 2020-11-08 | 公開日 | 2020-12-16 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (1.655 Å) | 主引用文献 | Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM. J.Struct.Biol., 213, 2021
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4XRL
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![BU of 4xrl by Molmil](/molmil-images/mine/4xrl) | Crystal structure at room temperature of Erk2 in complex with an inhibitor | 分子名称: | 1H-pyrrolo[2,3-b]pyridine-3-carbonitrile, Mitogen-activated protein kinase 1, SULFATE ION | 著者 | Gelin, M, Allemand, F, Labesse, G, Guichou, J.F. | 登録日 | 2015-01-21 | 公開日 | 2016-03-23 | 最終更新日 | 2016-03-30 | 実験手法 | X-RAY DIFFRACTION (2.554 Å) | 主引用文献 | Combining 'dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography. Acta Crystallogr.,Sect.D, 71, 2015
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5F47
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![BU of 5f47 by Molmil](/molmil-images/mine/5f47) | Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample in complex with trehalose | 分子名称: | CALCIUM ION, CHLORIDE ION, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, ... | 著者 | Xu, Z, Skarina, T, Wawrzak, Z, Stogios, P.J, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-12-03 | 公開日 | 2015-12-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.497 Å) | 主引用文献 | Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes. ACS Infect Dis, 3, 2017
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6SBA
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![BU of 6sba by Molmil](/molmil-images/mine/6sba) | Crystal Structure of mTEAD with a VGL4 Tertiary Structure Mimetic | 分子名称: | ACETYL GROUP, GLYCEROL, Transcriptional enhancer factor TEF-3, ... | 著者 | Adihou, H, Grossmann, T.N, Waldmann, H, Gasper, R. | 登録日 | 2019-07-19 | 公開日 | 2020-09-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | A protein tertiary structure mimetic modulator of the Hippo signalling pathway. Nat Commun, 11, 2020
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3O9S
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![BU of 3o9s by Molmil](/molmil-images/mine/3o9s) | Effector domain of influenza A/PR/8/34 NS1 | 分子名称: | Nonstructural protein 1 | 著者 | Kerry, P.S, Lewis, A, Hale, B.G, Hass, C, Taylor, M.A, Randall, R.E, Russell, R.J.M. | 登録日 | 2010-08-04 | 公開日 | 2011-05-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain. Plos One, 6, 2011
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6SLM
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![BU of 6slm by Molmil](/molmil-images/mine/6slm) | Crystal structure of full-length HPV31 E6 oncoprotein in complex with LXXLL peptide of ubiquitin ligase E6AP | 分子名称: | GLYCEROL, Maltose/maltodextrin-binding periplasmic protein,Protein E6,Ubiquitin-protein ligase E3A, ZINC ION, ... | 著者 | Conrady, M, Gogl, G, Cousido-Siah, A, Mitschler, A, Trave, G, Simon, C. | 登録日 | 2019-08-20 | 公開日 | 2020-09-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of High-Risk Papillomavirus 31 E6 Oncogenic Protein and Characterization of E6/E6AP/p53 Complex Formation. J.Virol., 95, 2020
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4XNC
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![BU of 4xnc by Molmil](/molmil-images/mine/4xnc) | Crystal structure at room temperature of cyclophilin D in complex with an inhibitor | 分子名称: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ethyl N-[(4-aminobenzyl)carbamoyl]glycinate | 著者 | Gelin, M, Allemand, F, Labesse, G, Guichou, J.F. | 登録日 | 2015-01-15 | 公開日 | 2015-08-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography. Acta Crystallogr.,Sect.D, 71, 2015
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4XYL
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6SMU
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![BU of 6smu by Molmil](/molmil-images/mine/6smu) | Structure of the native full-length HIV-1 capsid protein in helical assembly (-13,12) | 分子名称: | Gag protein | 著者 | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | 登録日 | 2019-08-22 | 公開日 | 2020-09-09 | 最終更新日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (5 Å) | 主引用文献 | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27, 2020
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5FB1
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6SL9
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2VKW
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![BU of 2vkw by Molmil](/molmil-images/mine/2vkw) | Human NCAM, FN3 domains 1 and 2 | 分子名称: | NEURAL CELL ADHESION MOLECULE 1,140 KDA ISOFORM, SULFATE ION | 著者 | Carafoli, F, Saffell, J.L, Hohenester, E. | 登録日 | 2008-01-04 | 公開日 | 2008-02-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Tandem Fibronectin Type 3 Domains of Neural Cell Adhesion Molecule J.Mol.Biol., 377, 2008
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7BUM
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![BU of 7bum by Molmil](/molmil-images/mine/7bum) | mcGAS bound with pGpA | 分子名称: | ADENOSINE MONOPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, ... | 著者 | Wang, B, Su, X.D. | 登録日 | 2020-04-07 | 公開日 | 2020-09-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.047 Å) | 主引用文献 | Mn2+Directly Activates cGAS and Structural Analysis Suggests Mn2+Induces a Noncanonical Catalytic Synthesis of 2'3'-cGAMP. Cell Rep, 32, 2020
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6SO4
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![BU of 6so4 by Molmil](/molmil-images/mine/6so4) | Fragment RZ132 in complex with MAP kinase p38-alpha | 分子名称: | (2~{S})-2-methyl-4-(oxetan-3-yl)-~{N}-(phenylmethyl)piperazine-2-carboxamide, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Nichols, C.E, De Nicola, G.F. | 登録日 | 2019-08-29 | 公開日 | 2019-09-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
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7BVL
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![BU of 7bvl by Molmil](/molmil-images/mine/7bvl) | |