5F47

Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample in complex with trehalose

Summary for 5F47

• Entry DOI: 10.2210/pdb5f47/pdb
• Related: 5F46 5F48 5F49 5U08
• Related PRD ID: PRD_900006
• Descriptor: aminoglycoside acetyltransferase meta-AAC0020, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: gnat fold, gcn5-n-acetyltransferase fold, acetyltransferase, aminoglycoside, antibiotic resistance, metagenome, soil, coenzyme a, structural genomics, center for structural genomics of infectious diseases, csgid, transferase
• Biological source: uncultured bacterium
• Total number of polymer chains: 2
• Total formula weight: 37787.80

Authors

Xu, Z.,Skarina, T.,Wawrzak, Z.,Stogios, P.J.,Yim, V.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2015-12-03, release date: 2015-12-30, Last modification date: 2024-03-06)

• Primary citation: Xu, Z.,Stogios, P.J.,Quaile, A.T.,Forsberg, K.J.,Patel, S.,Skarina, T.,Houliston, S.,Arrowsmith, C.,Dantas, G.,Savchenko, A.; Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes.; ACS Infect Dis, 3:653-665, 2017; PubMed: 28756664; DOI: 10.1021/acsinfecdis.7b00068

Experimental method

X-RAY DIFFRACTION (1.497 Å)