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3NY0
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Crystal Structure of UreE from Helicobacter pylori (Ni2+ bound form)
分子名称: NICKEL (II) ION, Urease accessory protein ureE
著者Shi, R, Munger, C, Assinas, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2010-07-14
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Crystal Structures of Apo and Metal-Bound Forms of the UreE Protein from Helicobacter pylori: Role of Multiple Metal Binding Sites
Biochemistry, 49, 2010
3T05
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BU of 3t05 by Molmil
Crystal structure of S. aureus Pyruvate Kinase
分子名称: PHOSPHATE ION, Pyruvate kinase
著者Worrall, L.J, Vuckovic, M, Strynadka, N.C.J.
登録日2011-07-19
公開日2011-10-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.
J.Biol.Chem., 286, 2011
5IOR
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BU of 5ior by Molmil
Flavin-dependent thymidylate synthase in complex with FAD and 2'-deoxyuridine-5'-monosulfate
分子名称: 2'-deoxy-5'-O-sulfouridine, FLAVIN-ADENINE DINUCLEOTIDE, RIBOFLAVIN, ...
著者Bernard, S.M, Stull, F.W, Smith, J.L.
登録日2016-03-08
公開日2016-06-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase.
Biochemistry, 55, 2016
6V24
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BU of 6v24 by Molmil
Complex of mutant (K162M) of E. coli L-asparaginase II with L-Asp. Covalent acyl-enzyme intermediate.
分子名称: ASPARTIC ACID, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-11-22
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
4W9Y
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BU of 4w9y by Molmil
X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a glutamyl sulfamide inhibitor CJC47
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Pavlicek, J, Barinka, C.
登録日2014-08-28
公開日2015-09-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural, Biochemical, and Computational Characterization of Sulfamides as Bimetallic Peptidase Inhibitors.
J.Chem.Inf.Model., 2024
6V2A
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BU of 6v2a by Molmil
Complex of double mutant (T89V,K162T) of E. coli L-asparaginase II with L-Asn
分子名称: ASPARAGINE, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-11-22
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
1RZM
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BU of 1rzm by Molmil
Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHPS) from Thermotoga maritima complexed with Cd2+, PEP and E4P
分子名称: CADMIUM ION, ERYTHOSE-4-PHOSPHATE, PHOSPHOENOLPYRUVATE, ...
著者Shumilin, I.A, Bauerle, R, Wu, J, Woodard, R.W, Kretsinger, R.H.
登録日2003-12-24
公開日2004-08-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Reaction Complex of 3-Deoxy-d-arabino-heptulosonate-7-phosphate Synthase from Thermotoga maritima Refines the Catalytic Mechanism and Indicates a New Mechanism of Allosteric Regulation.
J.Mol.Biol., 341, 2004
4UQQ
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BU of 4uqq by Molmil
Electron density map of GluK2 desensitized state in complex with 2S,4R-4-methylglutamate
分子名称: GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2, GLUTAMIC ACID
著者Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
登録日2014-06-24
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQJ
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Cryo-EM density map of GluA2em in complex with ZK200775
分子名称: GLUTAMATE RECEPTOR 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
著者Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
登録日2014-06-24
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (10.4 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
5EYV
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BU of 5eyv by Molmil
Crystal Structure of Adenylosuccinate lyase from Schistosoma mansoni in APO form.
分子名称: Adenylosuccinate lyase
著者Romanello, L, Torini, J.R, Bird, L.E, Nettleship, J.E, Owens, R.J, Reddivari, Y, Brandao-Neto, J, Pereira, H.M.
登録日2015-11-25
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
Mol. Biochem. Parasitol., 214, 2017
2C2O
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BU of 2c2o by Molmil
Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors.
分子名称: AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-14-{4-[BENZYL(METHYL) AMINO]-4-OXOBUTANOYL}-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN-16-OIC ACID, ...
著者Ganesan, R, Jelakovic, S, Ekici, O.D, Li, Z.Z, James, K.E, Asgian, J.L, Campbell, A, Mikolajczyk, J, Salvesen, G.S, Gruetter, M.G, Powers, J.C.
登録日2005-09-29
公開日2006-09-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10.
J.Med.Chem., 49, 2006
3NXZ
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BU of 3nxz by Molmil
Crystal Structure of UreE from Helicobacter pylori (Cu2+ bound form)
分子名称: COPPER (II) ION, Urease accessory protein ureE
著者Shi, R, Munger, C, Assinas, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2010-07-14
公開日2010-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of Apo and Metal-Bound Forms of the UreE Protein from Helicobacter pylori: Role of Multiple Metal Binding Sites
Biochemistry, 49, 2010
4W78
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BU of 4w78 by Molmil
Crystal structure of the ChsH1-ChsH2 complex from Mycobacterium tuberculosis
分子名称: CADMIUM ION, CALCIUM ION, CHLORIDE ION, ...
著者Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M.
登録日2014-08-21
公開日2014-10-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.541 Å)
主引用文献A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
3NNQ
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BU of 3nnq by Molmil
Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3
分子名称: ACETATE ION, N-terminal domain of Moloney murine leukemia virus integrase, ZINC ION
著者Guan, R, Xiao, R, Acton, T, Jiang, M, Roth, M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2010-06-24
公開日2010-07-14
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.693 Å)
主引用文献X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition.
Proteins, 85, 2017
1WLV
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BU of 1wlv by Molmil
Crystal structure of TT0310 protein from Thermus thermophilus HB8
分子名称: ACETATE ION, CHLORIDE ION, COENZYME A, ...
著者Kunishima, N, Sugahara, M, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-06-29
公開日2005-07-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Novel Induced-fit Reaction Mechanism of Asymmetric Hot Dog Thioesterase PaaI
J.Mol.Biol., 352, 2005
4UQK
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BU of 4uqk by Molmil
Electron density map of GluA2em in complex with quisqualate and LY451646
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2
著者Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
登録日2014-06-24
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (16.4 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
6V23
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BU of 6v23 by Molmil
Ligand-free L-aspraginase II from E. coli (EcAII)
分子名称: L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-11-22
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
6V2B
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BU of 6v2b by Molmil
Complex of double mutant (T89V,K162T) of E. coli L-asparaginase II with L-Asn
分子名称: ASPARAGINE, CITRIC ACID, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-11-22
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
1WM6
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BU of 1wm6 by Molmil
Crystal structure of TT0310 protein from Thermus thermophilus HB8
分子名称: CHLORIDE ION, phenylacetic acid degradation protein PaaI
著者Sugahara, M, Kunishima, N, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-07-04
公開日2005-07-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Novel Induced-fit Reaction Mechanism of Asymmetric Hot Dog Thioesterase PaaI
J.Mol.Biol., 352, 2005
3O03
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BU of 3o03 by Molmil
Quaternary complex structure of gluconate 5-dehydrogenase from streptococcus suis type 2
分子名称: CALCIUM ION, D-gluconic acid, Dehydrogenase with different specificities, ...
著者Peng, H, Gao, F, Zhang, Q, Liu, Y, Gao, G.F.
登録日2010-07-18
公開日2010-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insight Into the Catalytic Mechanism of Gluconate 5-Dehydrogenase from Streptococcus Suis: Crystal Structures of the Substrate-Free and Quaternary Complex Enzymes.
Protein Sci., 18, 2009
4Q31
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BU of 4q31 by Molmil
The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FORMIC ACID, ...
著者Tan, K, Bigelow, L, Jedrzejczak, R, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2014-04-10
公開日2014-05-07
最終更新日2017-03-08
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate.
Struct Dyn, 3, 2016
5FIG
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BU of 5fig by Molmil
APO-CSP3 (COPPER STORAGE PROTEIN 3) FROM BACILLUS SUBTILIS
分子名称: CSP3
著者Vita, N, Landolfi, G, Basle, A, Platsaki, S, Waldron, K, Dennison, C.
登録日2015-09-25
公開日2016-10-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Bacterial cytosolic proteins with a high capacity for Cu(I) that protect against copper toxicity.
Sci Rep, 6, 2016
8S5L
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BU of 8s5l by Molmil
Full-length human cystathionine beta-synthase, basal state, partially degraded tetramer
分子名称: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE
著者McCorvie, T.J, Yue, W.W.
登録日2024-02-23
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Architecture and regulation of filamentous human cystathionine beta-synthase.
Nat Commun, 15, 2024
6V29
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BU of 6v29 by Molmil
Complex of double mutant (T89V,K162T) of E. coli L-asparaginase II with L-Asp
分子名称: ASPARTIC ACID, GLYCEROL, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-11-22
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020
6V28
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Complex of double mutant (T89V,K162T) of E. coli L-asparaginase II with L-Asp
分子名称: GLYCEROL, IMIDAZOLE, L-asparaginase 2
著者Lubkowski, J, Wlodawer, A.
登録日2019-11-22
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mechanism of Catalysis by l-Asparaginase.
Biochemistry, 59, 2020

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