3T05

Crystal structure of S. aureus Pyruvate Kinase

Summary for 3T05

• Entry DOI: 10.2210/pdb3t05/pdb
• Related: 3T07 3T0T
• Descriptor: Pyruvate kinase, PHOSPHATE ION (2 entities in total)
• Functional Keywords: tetramer, glycolysis, transferase
• Biological source: Staphylococcus aureus subsp. aureus
• Total number of polymer chains: 4
• Total formula weight: 262462.64

Authors

Worrall, L.J.,Vuckovic, M.,Strynadka, N.C.J. (deposition date: 2011-07-19, release date: 2011-10-26, Last modification date: 2024-02-28)

• Primary citation: Zoraghi, R.,Worrall, L.,See, R.H.,Strangman, W.,Popplewell, W.L.,Gong, H.,Samaai, T.,Swayze, R.D.,Kaur, S.,Vuckovic, M.,Finlay, B.B.,Brunham, R.C.,McMaster, W.R.,Davies-Coleman, M.T.,Strynadka, N.C.,Andersen, R.J.,Reiner, N.E.; Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.; J.Biol.Chem., 286:44716-44725, 2011; PubMed: 22030393; DOI: 10.1074/jbc.M111.289033

Experimental method

X-RAY DIFFRACTION (3.05 Å)