5IOR
Flavin-dependent thymidylate synthase in complex with FAD and 2'-deoxyuridine-5'-monosulfate
Summary for 5IOR
| Entry DOI | 10.2210/pdb5ior/pdb |
| Related | 5IOQ 5IOS 5IOT |
| Descriptor | Thymidylate synthase ThyX, FLAVIN-ADENINE DINUCLEOTIDE, 2'-deoxy-5'-O-sulfouridine, ... (5 entities in total) |
| Functional Keywords | fad-dependent, nucleotide biosynthesis, reductive methylation, transferase |
| Biological source | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) |
| Total number of polymer chains | 1 |
| Total formula weight | 28973.86 |
| Authors | Bernard, S.M.,Stull, F.W.,Smith, J.L. (deposition date: 2016-03-08, release date: 2016-06-08, Last modification date: 2023-09-27) |
| Primary citation | Stull, F.W.,Bernard, S.M.,Sapra, A.,Smith, J.L.,Zuiderweg, E.R.,Palfey, B.A. Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase. Biochemistry, 55:3261-3269, 2016 Cited by PubMed: 27214228DOI: 10.1021/acs.biochem.6b00510 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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