5IOR
Flavin-dependent thymidylate synthase in complex with FAD and 2'-deoxyuridine-5'-monosulfate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thymidylate synthase ThyX | polymer | 232 | 27503.7 | 1 | UniProt (Q9WYT0) Pfam (PF02511) | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) | TSase |
| 2 | B (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 3 | C (A) | 2'-deoxy-5'-O-sulfouridine | non-polymer | 308.3 | 1 | Chemie (DUS) PubChem (119081693) | |||
| 4 | D (A) | RIBOFLAVIN | non-polymer | 376.4 | 1 | Chemie (RBF) PubChem (46782882) PubChem (59733797) PubChem (89260495) PubChem (176586505) PubChem (1561682) PubChem (493570) PubChem (6328150) PubChem (1072) PubChem (6759) PubChem (193301) PubChem (7048775) PubChem (7048776) PubChem (12304941) | |||
| 5 | E (A) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A: 1 - 220 (UniProt: Q9WYT0)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | initiating methionine |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Asp -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Ile -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27503.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1470.2 | |
| All* | Total formula weight | 28973.9 |
