5IOR

Flavin-dependent thymidylate synthase in complex with FAD and 2'-deoxyuridine-5'-monosulfate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Thymidylate synthase ThyX	polymer	232	27503.7	1	UniProt (Q9WYT0) Pfam (PF02511) In PDB	Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)	TSase
2	A	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	1	Chemie (FAD)
3	A	2'-deoxy-5'-O-sulfouridine	non-polymer		308.3	1	Chemie (DUS)
4	A	RIBOFLAVIN	non-polymer		376.4	1	Chemie (RBF)
5		water	water		18.0	98	Chemie (HOH)

Sequence modifications

A: 1 - 220 (UniProt: Q9WYT0)

PDB	External Database	Details
Met -11	-	initiating methionine
Gly -10	-	expression tag
Ser -9	-	expression tag
Asp -8	-	expression tag
Lys -7	-	expression tag
Ile -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	27503.7
Non-Polymers*	Number of molecules	3
	Total formula weight	1470.2
All*	Total formula weight	28973.9

*Water molecules are not included.