6V29
Complex of double mutant (T89V,K162T) of E. coli L-asparaginase II with L-Asp
Summary for 6V29
Entry DOI | 10.2210/pdb6v29/pdb |
Descriptor | L-asparaginase 2, ASPARTIC ACID, GLYCEROL, ... (4 entities in total) |
Functional Keywords | l-asparagine hydrolase, anti-cancer drug, inactive mutant, hydrolase |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 4 |
Total formula weight | 143312.29 |
Authors | Lubkowski, J.,Wlodawer, A. (deposition date: 2019-11-22, release date: 2020-05-20, Last modification date: 2023-10-11) |
Primary citation | Lubkowski, J.,Vanegas, J.,Chan, W.K.,Lorenzi, P.L.,Weinstein, J.N.,Sukharev, S.,Fushman, D.,Rempe, S.,Anishkin, A.,Wlodawer, A. Mechanism of Catalysis by l-Asparaginase. Biochemistry, 59:1927-1945, 2020 Cited by PubMed: 32364696DOI: 10.1021/acs.biochem.0c00116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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