PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3QTI	c-Met Kinase in Complex with NVP-BVU972 分子名称: 6-{[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl}quinoline, CHLORIDE ION, GLYCEROL, ... 著者 Appleton, B.A. 登録日 2011-02-22 公開日 2011-07-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients. Cancer Res., 71, 2011
3Q5P	Crystal structure of BmrR bound to Tetracycline 分子名称: 23 bp BmrR promoter DNA, GLYCEROL, Multidrug-efflux transporter 1 regulator, ... 著者 Bachas, S, Eginton, C, Gunio, G, Wade, H. 登録日 2010-12-29 公開日 2011-06-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.942 Å) 主引用文献 Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc.Natl.Acad.Sci.USA, 108, 2011
3Q6P	Salivary protein from Lutzomyia longipalpis. Selenomethionine derivative 分子名称: 43.2 kDa salivary protein, CITRIC ACID 著者 Andersen, J.F, Xu, X, Chang, B.W, Collin, N, Valenzuela, J.G, Ribeiro, J.M. 登録日 2011-01-03 公開日 2011-07-27 最終更新日 2019-10-23 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection. J.Biol.Chem., 286, 2011
3Q7H	Structure of the ClpP subunit of the ATP-dependent Clp Protease from Coxiella burnetii 分子名称: ATP-dependent Clp protease proteolytic subunit, CALCIUM ION, DI(HYDROXYETHYL)ETHER 著者 Anderson, S.M, Wawrzak, Z, Gordon, E, Hasseman, J, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-01-04 公開日 2011-01-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the ClpP subunit of the ATP-dependent Clp Protease from Coxiella burnetii To be Published
3Q80	Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) Complexed with CDP-ME 分子名称: 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, CHLORIDE ION, ... 著者 Reddy, M.C.M, Bruning, J.B, Thurman, C, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2011-01-05 公開日 2011-05-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Mycobacterium tuberculosis 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD): a candidate antitubercular drug target Proteins, 2011
3Q9E	Crystal structure of H159A APAH complexed with acetylspermine 分子名称: Acetylpolyamine amidohydrolase, N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]acetamide, POTASSIUM ION, ... 著者 Lombardi, P.M, Christianson, D.W. 登録日 2011-01-07 公開日 2011-03-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of prokaryotic polyamine deacetylase reveals evolutionary functional relationships with eukaryotic histone deacetylases . Biochemistry, 50, 2011
3Q9B	Crystal Structure of APAH complexed with M344 分子名称: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Acetylpolyamine amidohydrolase, DIMETHYL SULFOXIDE, ... 著者 Lombardi, P.M, Christianson, D.W. 登録日 2011-01-07 公開日 2011-03-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of prokaryotic polyamine deacetylase reveals evolutionary functional relationships with eukaryotic histone deacetylases . Biochemistry, 50, 2011
3QBH	Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors 分子名称: (4S)-4-(2-hydroxy-5-{[(3S,4S,5R)-4-hydroxy-1,1-dioxido-5-{[3-(propan-2-yl)benzyl]amino}tetrahydro-2H-thiopyran-3-yl]methyl}benzyl)-3-propyl-1,3-oxazolidin-2-one, Beta-secretase 1 著者 Rondeau, J.M. 登録日 2011-01-13 公開日 2011-03-23 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
3QBT	Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp 分子名称: Inositol polyphosphate 5-phosphatase OCRL-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Hou, X, Hagemann, N, Schoebel, S, Blankenfeldt, W, Goody, R.S, Erdmann, K.S, Itzen, A. 登録日 2011-01-14 公開日 2011-03-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1. Embo J., 30, 2011
3QC0	Crystal structure of a sugar isomerase (SMc04130) from SINORHIZOBIUM MELILOTI 1021 at 1.45 A resolution 分子名称: TETRAETHYLENE GLYCOL, UNKNOWN LIGAND, ZINC ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-01-14 公開日 2011-04-06 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of a sugar isomerase (SMc04130) from SINORHIZOBIUM MELILOTI 1021 at 1.45 A resolution To be published
3QCL	Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-hydroxybut-1-yn-1-yl)benzoic acid 分子名称: 2-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-hydroxybut-1-yn-1-yl)benzoic acid, Receptor-type tyrosine-protein phosphatase gamma 著者 Sheriff, S. 登録日 2011-01-16 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop J.Med.Chem., 54, 2011
3QCW	Structure of neurexin 1 alpha (domains LNS1-LNS6), no splice inserts 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neurexin-1-alpha 著者 Rudenko, G. 登録日 2011-01-17 公開日 2011-06-15 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 The Structure of Neurexin 1 alpha Reveals Features Promoting a Role as Synaptic Organizer Structure, 19, 2011
3QEC	Crystal structure of a putative carbohydrate binding protein (PA1324) from Pseudomonas aeruginosa at 2.61 A resolution 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Putative carbohydrate binding protein, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-01-20 公開日 2011-03-02 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Crystal structure of a putative carbohydrate binding protein (PA1324) from Pseudomonas aeruginosa at 2.61 A resolution To be published
3QH6	1.8A resolution structure of CT296 from Chlamydia trachomatis 分子名称: CT296, TETRAETHYLENE GLYCOL 著者 Kemege, K, Hickey, J, Lovell, S, Battaile, K.P, Zhang, Y, Hefty, P.S. 登録日 2011-01-25 公開日 2011-10-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Ab initio structural modeling of and experimental validation for Chlamydia trachomatis protein CT296 reveal structural similarity to Fe(II) 2-oxoglutarate-dependent enzymes. J.Bacteriol., 193, 2011
3QHB	Crystal structure of oxidized Symerythrin from Cyanophora paradoxa 分子名称: FE (III) ION, Symerythrin 著者 Cooley, R.B, Arp, D.J, Karplus, P.A. 登録日 2011-01-25 公開日 2011-05-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 A diiron protein autogenerates a valine-phenylalanine cross-link. Science, 332, 2011
3QJG	Epidermin biosynthesis protein EpiD from Staphylococcus aureus 分子名称: CHLORIDE ION, Epidermin biosynthesis protein EpiD, FLAVIN MONONUCLEOTIDE 著者 Osipiuk, J, Makowska-Grzyska, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-01-28 公開日 2011-02-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Epidermin biosynthesis protein EpiD from Staphylococcus aureus. To be Published
3QL1	Crystal Structure of Ribonuclease A Variant A4C/D83E/V118C 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Ribonuclease pancreatic, ... 著者 Arnold, U, Schoepfel, M. 登録日 2011-02-02 公開日 2012-02-29 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Significant stabilization of ribonuclease A by additive effects Febs J., 279, 2012
3QIK	Crystal structure of the first PDZ domain of PREX1 分子名称: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, UNKNOWN ATOM OR ION 著者 Shen, L, Tong, Y, Tempel, W, Li, Y, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) 登録日 2011-01-27 公開日 2011-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.285 Å) 主引用文献 Crystal structure of the first PDZ domain of PREX1 to be published
3QIS	Recognition of the F&H motif by the Lowe Syndrome protein OCRL 分子名称: Inositol polyphosphate 5-phosphatase OCRL-1, Protein FAM109A 著者 Pirruccello, M, Swan, L.E, Folta-Stogniew, E, De Camilli, P. 登録日 2011-01-27 公開日 2011-06-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Recognition of the F&H motif by the Lowe syndrome protein OCRL. Nat.Struct.Mol.Biol., 18, 2011
3QLI	Crystal Structure of RipA from Yersinia pestis 分子名称: ACETATE ION, Coenzyme A transferase 著者 Torres, R, Goulding, C.W. 登録日 2011-02-02 公開日 2012-01-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Biochemical, structural and molecular dynamics analyses of the potential virulence factor RipA from Yersinia pestis. Plos One, 6, 2011
3QN6	Crystal Structures of Escherichia coli Aspartate Aminotransferase Reconstituted with 1-Deaza-Pyridoxal 5'-Phosphate: Internal Aldimine and Stable L-Aspartate External Aldimine 分子名称: 1,2-ETHANEDIOL, Aspartate aminotransferase, SULFATE ION 著者 Griswold, W.R. 登録日 2011-02-08 公開日 2011-06-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal Structures of Aspartate Aminotransferase Reconstituted with 1-Deazapyridoxal 5'-Phosphate: Internal Aldimine and Stable l-Aspartate External Aldimine. Biochemistry, 50, 2011
3QOQ	Crystal Structure of the Transcription Factor AmrZ in Complex with the 18 Base Pair amrZ1 Binding Site 分子名称: Alginate and motility regulator Z, DNA (5'-D(*AP*CP*TP*GP*GP*CP*AP*AP*AP*AP*CP*GP*CP*CP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*GP*GP*CP*GP*TP*TP*TP*TP*GP*CP*CP*AP*GP*T)-3') 著者 Pryor Jr, E.E, Wozniak, D.J, Hollis, T. 登録日 2011-02-10 公開日 2012-02-15 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Transcription Factor AmrZ Utilizes Multiple DNA Binding Modes to Recognize Activator and Repressor Sequences of Pseudomonas aeruginosa Virulence Genes. Plos Pathog., 8, 2012
3QPZ	Crystal structure of the N59A mutant of the 3-deoxy-d-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, GLYCEROL, ... 著者 Allison, T.M, Jameson, G.B, Parker, E.J, Cochrane, F.C. 登録日 2011-02-14 公開日 2011-04-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase Biochemistry, 50, 2011
3QR1	Crystal Structure of L. pealei PLC21 分子名称: CALCIUM ION, PHOSPHOLIPASE C-BETA (PLC-BETA) 著者 Lyon, A.M, Suddala, K.C, Northup, J.K, Tesmer, J.J.G. 登録日 2011-02-16 公開日 2011-08-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 An autoinhibitory helix in the C-terminal region of phospholipase C-beta mediates Galphaq activation. Nat.Struct.Mol.Biol., 18, 2011
3QS7	Crystal structure of a human Flt3 ligand-receptor ternary complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FL cytokine receptor, SL cytokine 著者 Verstraete, K, Savvides, S.N. 登録日 2011-02-19 公開日 2011-03-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex. Blood, 118, 2011

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