3QIS
Recognition of the F&H motif by the Lowe Syndrome protein OCRL
Summary for 3QIS
Entry DOI | 10.2210/pdb3qis/pdb |
Descriptor | Inositol polyphosphate 5-phosphatase OCRL-1, Protein FAM109A (3 entities in total) |
Functional Keywords | dent disease, rac1, rab gtpases, appl1, ses2, endocytic pathway, golgi complex, hydrolase-protein binding complex, hydrolase/protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasmic vesicle, phagosome membrane : Q01968 Early endosome: Q8N4B1 |
Total number of polymer chains | 2 |
Total formula weight | 44243.66 |
Authors | Pirruccello, M.,Swan, L.E.,Folta-Stogniew, E.,De Camilli, P. (deposition date: 2011-01-27, release date: 2011-06-15, Last modification date: 2023-09-13) |
Primary citation | Pirruccello, M.,Swan, L.E.,Folta-Stogniew, E.,De Camilli, P. Recognition of the F&H motif by the Lowe syndrome protein OCRL. Nat.Struct.Mol.Biol., 18:789-795, 2011 Cited by PubMed: 21666675DOI: 10.1038/nsmb.2071 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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