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8XCP
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Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating NADP and GLU in the initial stage of reaction
分子名称: GAMMA-L-GLUTAMIC ACID, Glutamate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wakabayashi, T, Oide, M, Nakasako, M.
登録日2023-12-10
公開日2023-12-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献CryoEM-sampling of metastable conformations appearing in cofactor-ligand association and catalysis of glutamate dehydrogenase.
Sci Rep, 14, 2024
8XCY
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Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating NADP and GLU in the steady stage of reaction
分子名称: GAMMA-L-GLUTAMIC ACID, Glutamate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wakabayashi, T, Oide, M, Nakasako, M.
登録日2023-12-10
公開日2023-12-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献CryoEM-sampling of metastable conformations appearing in cofactor-ligand association and catalysis of glutamate dehydrogenase.
Sci Rep, 14, 2024
8XCT
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Cryo-EM structure of Glutamate dehydrogenase from Thermococcus profundus incorporating NADPH in the steady stage of reaction
分子名称: Glutamate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wakabayashi, T, Oide, M, Nakasako, M.
登録日2023-12-10
公開日2023-12-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献CryoEM-sampling of metastable conformations appearing in cofactor-ligand association and catalysis of glutamate dehydrogenase.
Sci Rep, 14, 2024
8R2I
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Cryo-EM Structure of native Photosystem II assembly intermediate from Chlamydomonas reinhardtii
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ...
著者Fadeeva, M, Klaiman, D, Kandiah, E, Nelson, N.
登録日2023-11-06
公開日2024-01-31
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of native photosystem II assembly intermediate from Chlamydomonas reinhardtii .
Front Plant Sci, 14, 2023
6DAX
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X-ray crystal structure of VioC bound to Fe(II), L-homoarginine, and 2-oxoglutarate
分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent L-arginine hydroxylase, FE (II) ION, ...
著者Dunham, N.P, Mitchell, A.J, Boal, A.K.
登録日2018-05-02
公開日2018-05-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of alpha-Heteroatom Assistance.
J. Am. Chem. Soc., 140, 2018
8Q1S
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BU of 8q1s by Molmil
Pathogenic mutations of human phosphorylation sites affect protein-protein interactions
分子名称: 1,2-ETHANEDIOL, 14-3-3 protein epsilon, BROMIDE ION, ...
著者Roske, Y, Daumke, O, Rrustemi, T, Selbach, M.
登録日2023-08-01
公開日2024-02-21
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Pathogenic mutations of human phosphorylation sites affect protein-protein interactions.
Nat Commun, 15, 2024
4YA1
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Yeast 20S proteasome beta2-H116N mutant
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Groll, M.
登録日2015-02-17
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4YSY
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Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with N-[(2,4-dichlorophenyl)methyl]-2-(trifluoromethyl)benzamide
分子名称: Cytochrome b-large subunit, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ...
著者Harada, S, Shiba, T, Sato, D, Yamamoto, A, Nagahama, M, Yone, A, Inaoka, D.K, Sakamoto, K, Inoue, M, Honma, T, Kita, K.
登録日2015-03-17
公開日2015-08-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
Int J Mol Sci, 16, 2015
8PXU
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Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood
分子名称: Beta-N-acetylhexosaminidase, CACODYLATE ION
著者Jensen, M, Abou Hachem, M, Morth, J.P.
登録日2023-07-24
公開日2024-02-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood.
Nat Microbiol, 9, 2024
8PXV
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BU of 8pxv by Molmil
Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood
分子名称: Beta-N-acetylhexosaminidase, GLYCEROL, SODIUM ION, ...
著者Weikum, J, Jensen, M, Abou Hachem, M, Morth, J.P.
登録日2023-07-24
公開日2024-02-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood.
Nat Microbiol, 9, 2024
8PXT
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BU of 8pxt by Molmil
Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ...
著者Jensen, M, Abou Hachem, M, Morth, J.P.
登録日2023-07-24
公開日2024-02-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood.
Nat Microbiol, 9, 2024
3FRL
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BU of 3frl by Molmil
The 2.25 A crystal structure of LipL32, the major surface antigen of Leptospira interrogans serovar Copenhageni
分子名称: 2,2',2''-NITRILOTRIETHANOL, CHLORIDE ION, LipL32, ...
著者Farah, C.S, Guzzo, C.R, Hauk, P, Ho, P.L.
登録日2009-01-08
公開日2009-06-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure and calcium-binding activity of LipL32, the major surface antigen of pathogenic Leptospira sp.
J.Mol.Biol., 390, 2009
8PVS
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BU of 8pvs by Molmil
Targeting extended blood antigens by Akkermansia muciniphila enzymes unveils a missing link for generating universal donor blood
分子名称: 1,2-ETHANEDIOL, Alpha-1,3-galactosidase B, CALCIUM ION, ...
著者Jensen, M, Abou Hachem, M, Morth, J.P.
登録日2023-07-18
公開日2024-02-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood.
Nat Microbiol, 9, 2024
8QXI
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BU of 8qxi by Molmil
SipA solution structure
分子名称: Uncharacterized protein SEF0032
著者Neira, J.L.
登録日2023-10-24
公開日2024-03-06
実験手法SOLUTION NMR
主引用文献Structure and dynamics of the cyanobacterial regulator SipA.
Arch.Biochem.Biophys., 754, 2024
4RPK
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BU of 4rpk by Molmil
Crystal structure of Micobacterium tuberculosis UDP-Galactopyranose mutase in complex with tetrafluorinated substrate analog UDP-F4-Galf
分子名称: (2R,5S)-5-[(1R)-1,2-dihydroxyethyl]-3,3,4,4-tetrafluorotetrahydrofuran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name), FLAVIN-ADENINE DINUCLEOTIDE, UDP-galactopyranose mutase
著者Van Straaten, K.E, Sanders, D.A.R.
登録日2014-10-30
公開日2015-01-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from Mycobacterium tuberculosis Using Substrate and Tetrafluorinated Substrate Analogues.
J.Am.Chem.Soc., 137, 2015
4Y5R
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BU of 4y5r by Molmil
Crystal Structure of a T67A MauG/pre-Methylamine Dehydrogenase Complex
分子名称: CALCIUM ION, HEME C, Methylamine dehydrogenase heavy chain, ...
著者Li, C, Wilmot, C.M.
登録日2015-02-11
公開日2015-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A T67A mutation in the proximal pocket of the high-spin heme of MauG stabilizes formation of a mixed-valent Fe(II)/Fe(III) state and enhances charge resonance stabilization of the bis-Fe(IV) state.
Biochim.Biophys.Acta, 1847, 2015
4Y70
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BU of 4y70 by Molmil
Yeast 20S proteasome in complex with Ac-LAV-ep
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAV-ep, CHLORIDE ION, ...
著者Huber, E.M, Groll, M.
登録日2015-02-13
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y8P
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BU of 4y8p by Molmil
Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAL-ep
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-PAL-ep, CHLORIDE ION, ...
著者Huber, E.M, Groll, M.
登録日2015-02-16
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y9Y
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BU of 4y9y by Molmil
Yeast 20S proteasome beta2-H116E mutant
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Proteasome subunit alpha type-1, ...
著者Huber, E.M, Groll, M.
登録日2015-02-17
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
8UJM
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BU of 8ujm by Molmil
Crystal structure of human CTDNEP1-NEP1R1 protein phosphatase complex with magnesium
分子名称: CTD nuclear envelope phosphatase 1,Nuclear envelope phosphatase-regulatory subunit 1, MAGNESIUM ION
著者Gao, S, Airola, M.V.
登録日2023-10-11
公開日2024-05-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.161 Å)
主引用文献Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology.
Proc.Natl.Acad.Sci.USA, 121, 2024
8PUO
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BU of 8puo by Molmil
Structural determinants of cold-activity and glucose tolerance of a family 1 glycoside hydrolase (GH1) from Antarctic Marinomonas Ef 1
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucosidase
著者Gourlay, L.J, Nardini, M.
登録日2023-07-17
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural determinants of cold activity and glucose tolerance of a family 1 glycoside hydrolase (GH1) from Antarctic Marinomonas sp. ef1.
Febs J., 2024
7OJM
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BU of 7ojm by Molmil
CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) CATALYTICALLY INACTIVE H251A VARIANT COMPLEXED WITH 2-METHYL-QUINOLIN-4(1H)-ONE UNDER NORMOXIC CONDITIONS
分子名称: 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, 2-methyl-quinolin-4(1H)-one, GLYCEROL, ...
著者Bui, S, Steiner, R.A.
登録日2021-05-16
公開日2022-06-01
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Evolutionary adaptation from hydrolytic to oxygenolytic catalysis at the alpha / beta-hydrolase fold.
Chem Sci, 14, 2023
4YLW
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Crystal structure of human dihydroorotate dehydrogenase (DHODH) with No.33 compound
分子名称: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
著者Wu, D, Ouyang, P, Lu, W, Huang, J.
登録日2015-03-06
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal structure of human dihydroorotate dehydrogenase (DHODH) with No.33 compound
To Be Published
4YNI
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BU of 4yni by Molmil
Iron free succinate bound rat cysteine dioxygenase
分子名称: Cysteine dioxygenase type 1, SODIUM ION, SUCCINIC ACID
著者Fellner, M, Tchesnokov, E.P, Jameson, G.N.L, Wilbanks, S.M.
登録日2015-03-10
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.404 Å)
主引用文献Iron free succinate bound rat cysteine dioxygenase
To be published
4E9T
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BU of 4e9t by Molmil
Multicopper Oxidase CueO (data6)
分子名称: ACETATE ION, Blue copper oxidase CueO, COPPER (II) ION
著者Komori, H, Kataoka, K, Sakurai, T, Higuchi, Y.
登録日2012-03-21
公開日2013-05-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure and function of the engineered multicopper oxidase CueO from Escherichia coli--deletion of the methionine-rich helical region covering the substrate-binding site.
J.Mol.Biol., 373, 2007

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